Cytolethal distending toxin-induced cell cycle arrest of lymphocytes is dependent upon recognition and binding to cholesterol K Boesze-Battaglia, A Brown, L Walker, D Besack, A Zekavat, S Wrenn, ... Journal of biological chemistry 284 (16), 10650-10658, 2009 | 93 | 2009 |
Applications of catechins in the treatment of bacterial infections M Wu, AC Brown Pathogens 10 (5), 546, 2021 | 61 | 2021 |
Aggregatibacter actinomycetemcomitans leukotoxin utilizes a cholesterol recognition/amino acid consensus site for membrane association AC Brown, NV Balashova, RM Epand, RF Epand, A Bragin, SC Kachlany, ... Journal of Biological Chemistry 288 (32), 23607-23621, 2013 | 59 | 2013 |
Aggregatibacter actinomycetemcomitans Leukotoxin Is Delivered to Host Cells in an LFA-1-Indepdendent Manner When Associated with Outer Membrane Vesicles JB Nice, NV Balashova, SC Kachlany, E Koufos, E Krueger, ET Lally, ... Toxins 10 (10), 414, 2018 | 48 | 2018 |
Measuring raft size as a function of membrane composition in PC-based systems: part 1− binary systems AC Brown, KB Towles, SP Wrenn Langmuir 23 (22), 11180-11187, 2007 | 46 | 2007 |
Bacterial outer membrane vesicles as antibiotic delivery vehicles SM Collins, AC Brown Frontiers in immunology 12, 733064, 2021 | 43 | 2021 |
Catechin-mediated restructuring of a bacterial toxin inhibits activity EH Chang, J Huang, Z Lin, AC Brown Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (1), 191-198, 2019 | 42 | 2019 |
Measuring Raft Size as a Function of Membrane Composition in PC-Based Systems: Part II Ternary Systems AC Brown, KB Towles, SP Wrenn Langmuir 23 (22), 11188-11196, 2007 | 41 | 2007 |
Disorder in Cholesterol-Binding Functionality of CRAC Peptides: A Molecular Dynamics Study CM Miller, J Brown, Angela C., Mittal Journal of Physical Chemistry B 118 (46), 13174, 2014 | 39 | 2014 |
Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization AC Brown, K Boesze‐Battaglia, Y Du, FP Stefano, IR Kieba, RF Epand, ... Cellular microbiology 14 (6), 869-881, 2012 | 38 | 2012 |
Inhibition of LtxA toxicity by blocking cholesterol binding with peptides AC Brown, E Koufos, NV Balashova, K Boesze‐Battaglia, ET Lally Molecular oral microbiology 31 (1), 94-105, 2016 | 35 | 2016 |
Aggregatibacter actinomycetemcomitans leukotoxin is post‐translationally modified by addition of either saturated or hydroxylated fatty acyl chains KP Fong, HY Tang, AC Brown, IR Kieba, DW Speicher, ... Molecular oral microbiology 26 (4), 262-276, 2011 | 35 | 2011 |
Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding A Osickova, N Balashova, J Masin, M Sulc, J Roderova, T Wald, ... Emerging microbes & infections 7 (1), 1-15, 2018 | 34 | 2018 |
Association of Vibrio cholerae 569B outer membrane vesicles with host cells occurs in a GM1‐independent manner ES Rasti, ML Schappert, AC Brown Cellular microbiology 20 (6), e12828, 2018 | 34 | 2018 |
Inhibition of bacterial toxin recognition of membrane components as an anti-virulence strategy E Krueger, AC Brown Journal of Biological Engineering 13 (1), 4, 2019 | 26 | 2019 |
Effect of membrane microheterogeneity and domain size on fluorescence resonance energy transfer KB Towles, AC Brown, SP Wrenn, N Dan Biophysical journal 93 (2), 655-667, 2007 | 26 | 2007 |
Use of a cholesterol recognition amino acid consensus peptide to inhibit binding of a bacterial toxin to cholesterol E Koufos, EH Chang, ES Rasti, E Krueger, AC Brown Biochemistry 55 (34), 4787-4797, 2016 | 25 | 2016 |
Aggregatibacter actinomycetemcomitans leukotoxin: From mechanism to targeted anti‐toxin therapeutics E Krueger, AC Brown Molecular oral microbiology 35 (3), 85-105, 2020 | 22 | 2020 |
Receptor-based peptides for inhibition of leukotoxin activity E Krueger, S Hayes, EH Chang, S Yutuc, AC Brown ACS Infectious Diseases 4 (7), 1073-1081, 2018 | 22 | 2018 |
Epigallocatechin gallate inhibits leukotoxin release by Aggregatibacter actinomycetemcomitans by promoting association with the bacterial membrane EH Chang, P Giaquinto, J Huang, NV Balashova, AC Brown Molecular oral microbiology 35 (1), 29-39, 2020 | 20 | 2020 |