| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13122* | 2021 |
| Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade P Li, D Nijhawan, I Budihardjo, SM Srinivasula, M Ahmad, ES Alnemri, ... cell 91 (4), 479-489, 1997 | 9429 | 1997 |
| IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases QL Deveraux, N Roy, HR Stennicke, T Van Arsdale, Q Zhou, ... The EMBO journal, 1998 | 1930 | 1998 |
| Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells JL Wang, D Liu, ZJ Zhang, S Shan, X Han, SM Srinivasula, CM Croce, ... Proceedings of the National Academy of Sciences 97 (13), 7124-7129, 2000 | 1568 | 2000 |
| Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization SM Srinivasula, M Ahmad, T Fernandes-Alnemri, ES Alnemri Molecular cell 1 (7), 949-957, 1998 | 1526 | 1998 |
| A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis SM Srinivasula, R Hegde, A Saleh, P Datta, E Shiozaki, J Chai, RA Lee, ... Nature 410 (6824), 112-116, 2001 | 1389 | 2001 |
| Negative regulation of the Apaf-1 apoptosome by Hsp70 A Saleh, SM Srinivasula, L Balkir, PD Robbins, ES Alnemri Nature cell biology 2 (8), 476-483, 2000 | 1099 | 2000 |
| In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. T Fernandes-Alnemri, RC Armstrong, J Krebs, SM Srinivasula, L Wang, ... Proceedings of the National Academy of Sciences 93 (15), 7464-7469, 1996 | 1022 | 1996 |
| Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction R Hegde, SM Srinivasula, ZJ Zhang, R Wassell, R Mukattash, L Cilenti, ... Journal of Biological Chemistry 277 (1), 432-438, 2002 | 1021 | 2002 |
| Mechanism of XIAP-mediated inhibition of caspase-9 EN Shiozaki, J Chai, DJ Rigotti, SJ Riedl, P Li, SM Srinivasula, ... Molecular cell 11 (2), 519-527, 2003 | 960 | 2003 |
| Structural basis of caspase-7 inhibition by XIAP J Chai, E Shiozaki, SM Srinivasula, Q Wu, P Dataa, ES Alnemri, Y Shi Cell 104 (5), 769-780, 2001 | 792 | 2001 |
| Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL M MacFarlane, M Ahmad, SM Srinivasula, T Fernandes-Alnemri, ... Journal of Biological Chemistry 272 (41), 25417-25420, 1997 | 790 | 1997 |
| Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90 P Pandey, A Saleh, A Nakazawa, S Kumar, SM Srinivasula, V Kumar, ... The EMBO journal, 2000 | 760 | 2000 |
| Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases SM Srinivasula, M Ahmad, T Fernandes-Alnemri, G Litwack, ES Alnemri Proceedings of the National Academy of Sciences 93 (25), 14486-14491, 1996 | 756 | 1996 |
| The PYRIN-CARD protein ASC is an activating adaptor for caspase-1 SM Srinivasula, JL Poyet, M Razmara, P Datta, ZJ Zhang, ES Alnemri Journal of Biological Chemistry 277 (24), 21119-21122, 2002 | 707 | 2002 |
| Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation A Saleh, SM Srinivasula, S Acharya, R Fishel, ES Alnemri Journal of Biological Chemistry 274 (25), 17941-17945, 1999 | 690 | 1999 |
| Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria Y Guo, SM Srinivasula, A Druilhe, T Fernandes-Alnemri, ES Alnemri Journal of Biological Chemistry 277 (16), 13430-13437, 2002 | 667 | 2002 |
| Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation CJ Wu, DB Conze, T Li, SM Srinivasula, JD Ashwell Nature cell biology 8 (4), 398-406, 2006 | 652 | 2006 |
| IAPs: what's in a name? SM Srinivasula, JD Ashwell Molecular cell 30 (2), 123-135, 2008 | 626 | 2008 |
| The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity G van Loo, M van Gurp, B Depuydt, SM Srinivasula, I Rodriguez, ... Cell Death & Differentiation 9 (1), 20-26, 2002 | 545 | 2002 |
