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Haopeng Wang
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Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling
S Vallabhapurapu, A Matsuzawa, WZ Zhang, PH Tseng, JJ Keats, ...
Nature immunology 9 (12), 1364-1370, 2008
7282008
ZAP-70: an essential kinase in T-cell signaling
H Wang, TA Kadlecek, BB Au-Yeung, HES Goodfellow, LY Hsu, ...
Cold Spring Harbor perspectives in biology 2 (5), a002279, 2010
4552010
Essential cytoplasmic translocation of a cytokine receptor–assembled signaling complex
A Matsuzawa, PH Tseng, S Vallabhapurapu, JL Luo, W Zhang, H Wang, ...
Science 321 (5889), 663-668, 2008
2662008
Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210
H Wang, H Flach, M Onizawa, L Wei, MT McManus, A Weiss
Nature immunology 15 (4), 393-401, 2014
2652014
A proximity-tagging system to identify membrane protein–protein interactions
Q Liu, J Zheng, W Sun, Y Huo, L Zhang, P Hao, H Wang, M Zhuang
Nature methods 15 (9), 715-722, 2018
1732018
Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity
J Holst, H Wang, KD Eder, CJ Workman, KL Boyd, Z Baquet, H Singh, ...
Nature immunology 9 (6), 658-666, 2008
1732008
Substrates of IAP ubiquitin ligases identified with a designed orthogonal E3 ligase, the NEDDylator
M Zhuang, S Guan, H Wang, AL Burlingame, JA Wells
Molecular cell 49 (2), 273-282, 2013
1282013
Multiple signaling roles of CD3ε and its application in CAR-T cell therapy
W Wu, Q Zhou, T Masubuchi, X Shi, H Li, X Xu, M Huang, L Meng, X He, ...
Cell 182 (4), 855-871. e23, 2020
1162020
Combined Immunodeficiency Due to MALT1 Mutations, Treated by Hematopoietic Cell Transplantation
D Punwani, H Wang (co-1st author), AY Chan, MJ Cowan, J Mallott, ...
Journal of clinical immunology 35 (2), 135-146, 2015
1082015
Chimeric antigen receptor designed to prevent ubiquitination and downregulation showed durable antitumor efficacy
W Li, S Qiu, J Chen, S Jiang, W Chen, J Jiang, F Wang, W Si, Y Shu, ...
Immunity 53 (2), 456-470. e6, 2020
1032020
Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation
W Shang, Y Jiang, M Boettcher, K Ding, M Mollenauer, Z Liu, X Wen, ...
Proceedings of the National Academy of Sciences 115 (17), E4051-E4060, 2018
932018
Ionic CD3− Lck interaction regulates the initiation of T-cell receptor signaling
L Li, X Guo, X Shi, C Li, W Wu, C Yan, H Wang, H Li, C Xu
Proceedings of the National Academy of Sciences 114 (29), E5891-E5899, 2017
922017
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2
X Xu, B Hou, A Fulzele, T Masubuchi, Y Zhao, Z Wu, Y Hu, Y Jiang, Y Ma, ...
Journal of Cell Biology 219 (6), e201905085, 2020
872020
Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin
H Wang, A Matsuzawa, SA Brown, JR Zhou, CS Guy, PH Tseng, K Forbes, ...
Proceedings of the National Academy of Sciences 105 (51), 20197-20202, 2008
732008
Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor
R Tian, H Wang (co-1st author), GD Gish, E Petsalaki, A Pasculescu, ...
Proceedings of the National Academy of Sciences, 201503286, 2015
712015
Tonic ubiquitylation controls T‐cell receptor: CD3 complex expression during T‐cell development
H Wang, J Holst, SR Woo, C Guy, M Bettini, Y Wang, A Shafer, ...
The EMBO journal 29 (7), 1285-1298, 2010
592010
NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
Y Wang, F Wang, L Wang, S Qiu, Y Yao, C Yan, X Xiong, X Chen, Q Ji, ...
Cell reports 36 (6), 2021
542021
Dynamic regulation of CD28 conformation and signaling by charged lipids and ions
W Yang, W Pan, S Chen, N Trendel, S Jiang, F Xiao, M Xue, W Wu, ...
Nature Structural & Molecular Biology 24 (12), 1081-1092, 2017
512017
Antigen receptor nanoclusters: small units with big functions
W Liu, H Wang, C Xu
Trends in immunology 37 (10), 680-689, 2016
362016
Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness
J Chen, S Qiu, W Li, K Wang, Y Zhang, H Yang, B Liu, G Li, L Li, M Chen, ...
Cell Research 33 (5), 341-354, 2023
312023
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