| The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation A Dhayalan, A Rajavelu, P Rathert, R Tamas, RZ Jurkowska, S Ragozin, ... Journal of Biological Chemistry 285 (34), 26114-26120, 2010 | 643 | 2010 |
| Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail Y Zhang, R Jurkowska, S Soeroes, A Rajavelu, A Dhayalan, I Bock, ... Nucleic acids research 38 (13), 4246-4253, 2010 | 480 | 2010 |
| Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a–Dnmt3L single-chain fusion protein with increased DNA methylation activity AN Siddique, S Nunna, A Rajavelu, Y Zhang, RZ Jurkowska, R Reinhardt, ... Journal of molecular biology 425 (3), 479-491, 2013 | 199 | 2013 |
| Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L RZ Jurkowska, A Rajavelu, N Anspach, C Urbanke, G Jankevicius, ... Journal of Biological Chemistry 286 (27), 24200-24207, 2011 | 128 | 2011 |
| Synthesis and Evaluation of Analogues of N-Phthaloyl-l-tryptophan (RG108) as Inhibitors of DNA Methyltransferase 1 S Asgatay, C Champion, G Marloie, T Drujon, C Senamaud-Beaufort, ... Journal of medicinal chemistry 57 (2), 421-434, 2014 | 109 | 2014 |
| C5‐DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development A Ceccaldi, A Rajavelu, C Champion, C Rampon, R Jurkowska, ... Chembiochem 12 (9), 1337-1345, 2011 | 92 | 2011 |
| Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a R Deplus, L Blanchon, A Rajavelu, A Boukaba, M Defrance, J Luciani, ... Cell reports 8 (3), 743-753, 2014 | 84 | 2014 |
| The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols A Rajavelu, Z Tulyasheva, R Jaiswal, A Jeltsch, N Kuhnert BMC biochemistry 12, 1-8, 2011 | 81 | 2011 |
| Rapid synthesis of new DNMT inhibitors derivatives of procainamide L Halby, C Champion, C Sénamaud‐Beaufort, S Ajjan, T Drujon, ... Chembiochem 13 (1), 157-165, 2012 | 75 | 2012 |
| Design, Synthesis and Biological Evaluation of 4‐Amino‐N‐(4‐aminophenyl)benzamide Analogues of Quinoline‐Based SGI‐1027 as Inhibitors of DNA Methylation E Rilova, A Erdmann, C Gros, V Masson, Y Aussagues, ... ChemMedChem 9 (3), 590-601, 2014 | 66 | 2014 |
| Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation A Rajavelu, RZ Jurkowska, J Fritz, A Jeltsch Nucleic acids research 40 (2), 569-580, 2012 | 66 | 2012 |
| Identification of novel inhibitors of DNA methylation by screening of a chemical library A Ceccaldi, A Rajavelu, S Ragozin, C Sénamaud-Beaufort, P Bashtrykov, ... ACS chemical biology 8 (3), 543-548, 2013 | 65 | 2013 |
| Genetic and epigenetic mechanisms in the development of arteriovenous malformations in the brain JM Thomas, S Surendran, M Abraham, A Rajavelu, CC Kartha Clinical epigenetics 8, 1-8, 2016 | 64 | 2016 |
| Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase M Emperle, A Rajavelu, R Reinhardt, RZ Jurkowska, A Jeltsch Journal of Biological Chemistry 289 (43), 29602-29613, 2014 | 62 | 2014 |
| The DNMT3A R882H mutant displays altered flanking sequence preferences M Emperle, A Rajavelu, S Kunert, PB Arimondo, R Reinhardt, ... Nucleic acids research 46 (6), 3130-3139, 2018 | 54 | 2018 |
| Localisation of Plasmodium falciparum uroporphyrinogen III decarboxylase of the heme-biosynthetic pathway in the apicoplast and characterisation of its catalytic properties VA Nagaraj, R Arumugam, NR Chandra, D Prasad, PN Rangarajan, ... International journal for parasitology 39 (5), 559-568, 2009 | 48 | 2009 |
| Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain P Bashtrykov, A Rajavelu, B Hackner, S Ragozin, T Carell, A Jeltsch Chembiochem 15 (5), 743-748, 2014 | 46 | 2014 |
| Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2 A Rajavelu, C Lungu, M Emperle, M Dukatz, A Bröhm, J Broche, I Hanelt, ... Nucleic acids research 46 (17), 9044-9056, 2018 | 44 | 2018 |
| Unique properties of Plasmodium falciparum porphobilinogen deaminase VA Nagaraj, R Arumugam, B Gopalakrishnan, YS Jyothsna, ... Journal of Biological Chemistry 283 (1), 437-444, 2008 | 43 | 2008 |
| The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes M Emperle, M Dukatz, S Kunert, K Holzer, A Rajavelu, RZ Jurkowska, ... Scientific reports 8 (1), 13242, 2018 | 41 | 2018 |
Albert JeltschProf. of Biochemistry, Institute of Biochemistry and Technical Biochemistry, University of StuttgartVerified email at ibtb.uni-stuttgart.de
