Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells Q Wu, S Sharma, H Cui, SE LeBlanc, H Zhang, R Muthuswami, ... Oncotarget 7 (19), 27158, 2016 | 63 | 2016 |
The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation Q Wu, P Madany, JR Dobson, JM Schnabl, S Sharma, TC Smith, ... Oncotarget 7 (25), 38270, 2016 | 62 | 2016 |
A eukaryotic SWI2/SNF2 domain, an exquisite detector of double-stranded to single-stranded DNA transition elements R Muthuswami, PA Truman, LD Mesner, JW Hockensmith Journal of Biological Chemistry 275 (11), 7648-7655, 2000 | 56 | 2000 |
BRG1 is a prognostic indicator and a potential therapeutic target for prostate cancer R Muthuswami, LA Bailey, R Rakesh, AN Imbalzano, JA Nickerson, ... Journal of Cellular Physiology 234 (9), 15194-15205, 2019 | 34 | 2019 |
Phosphoaminoglycosides inhibit SWI2/SNF2 family DNA-dependent molecular motor domains R Muthuswami, LD Mesner, D Wang, DA Hill, AN Imbalzano, ... Biochemistry 39 (15), 4358-4365, 2000 | 34 | 2000 |
BRG1 and SMARCAL1 transcriptionally co-regulate DROSHA, DGCR8 and DICER in response to doxorubicin-induced DNA damage K Patne, R Rakesh, V Arya, UB Chanana, R Sethy, PB Swer, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1860 (9), 936-951, 2017 | 32 | 2017 |
SMARCAL1 Negatively Regulates C-Myc Transcription By Altering The Conformation Of The Promoter Region T Sharma, R Bansal, DT Haokip, I Goel, R Muthuswami Scientific Reports 5 (1), 17910, 2015 | 32 | 2015 |
The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity N Mittal, R Muthuswami, R Madhubala PLoS Neglected Tropical Diseases 11 (5), e0005590, 2017 | 30 | 2017 |
Global epigenetic changes induced by SWI2/SNF2 inhibitors characterize neomycin-resistant mammalian cells P Dutta, GK Tanti, S Sharma, SK Goswami, SS Komath, MW Mayo, ... PloS one 7 (11), e49822, 2012 | 30 | 2012 |
The HIV plus-strand transfer reaction: determination of replication-competent intermediates and identification of a novel lentiviral element, the primer over-extension sequence1 R Muthuswami, J Chen, BP Burnett, RL Thimmig, N Janjic, CS McHenry Journal of molecular biology 315 (3), 311-323, 2002 | 27 | 2002 |
Transcriptional regulation of Atp-dependent chromatin remodeling factors: Smarcal1 and Brg1 mutually co-regulate each other DT Haokip, I Goel, V Arya, T Sharma, R Kumari, R Priya, M Singh, ... Scientific Reports 6 (1), 20532, 2016 | 26 | 2016 |
Motifs Q and I Are Required for ATP Hydrolysis but Not for ATP Binding in SWI2/SNF2 Proteins M Nongkhlaw, M Gupta, SS Komath, R Muthuswami Biochemistry, 2012 | 24 | 2012 |
Elucidating the mechanism of DNA-dependent ATP hydrolysis mediated by DNA-dependent ATPase A, a member of the SWI2/SNF2 protein family M Nongkhlaw, P Dutta, JW Hockensmith, SS Komath, R Muthuswami Nucleic acids research 37 (10), 3332-3341, 2009 | 21 | 2009 |
Among the three striatin family members, SG2NA was first to arise during evolution GK Tanti, N Singarapu, R Muthuswami, SK Goswami Front Biosci Sch Ed 6, 1-15, 2014 | 20 | 2014 |
Regulation of ATM and ATR by SMARCAL1 and BRG1 R Sethy, R Rakesh, K Patne, V Arya, T Sharma, DT Haokip, R Kumari, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (12 …, 2018 | 19 | 2018 |
Epigenetic regulation of defense genes by histone deacetylase1 in human cell line-derived macrophages promotes intracellular survival of Leishmania donovani G Roy, HK Brar, R Muthuswami, R Madhubala PLoS Neglected Tropical Diseases 14 (4), e0008167, 2020 | 16 | 2020 |
A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance … R Bansal, SS Sen, R Muthuswami, R Madhubala PLOS Neglected Tropical Diseases 13 (4), e0007260, 2019 | 15 | 2019 |
The GPI Anchor Signal Sequence Dictates the Folding and Functionality of the Als5 Adhesin from Candida albicans MF Ahmad, B Yadav, P Kumar, A Puri, M Mazumder, A Ali, S Gourinath, ... PLoS One 7 (4), e35305, 2012 | 15 | 2012 |
Stigmasterol as a potential biomarker for amphotericin B resistance in Leishmania donovani R Bansal, SS Sen, R Muthuswami, R Madhubala Journal of Antimicrobial Chemotherapy 75 (4), 942-950, 2020 | 14 | 2020 |
SMARCAL1, the annealing helicase and the transcriptional co‐regulator R Bansal, S Hussain, UB Chanana, D Bisht, I Goel, R Muthuswami Iubmb Life 72 (10), 2080-2096, 2020 | 13 | 2020 |