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Nils Wierup
Nils Wierup
Unknown affiliation
Verified email at med.lu.se
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Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
V Lyssenko, CLF Nagorny, MR Erdos, N Wierup, A Jonsson, P Spégel, ...
Nature genetics 41 (1), 82-88, 2009
8472009
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
M Lundblad, M Andersson, C Winkler, D Kirik, N Wierup, MA Cenci
European Journal of Neuroscience 15 (1), 120-132, 2002
7792002
The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas
N Wierup, H Svensson, H Mulder, F Sundler
Regulatory peptides 107 (1-3), 63-69, 2002
6812002
Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes
MD Nitert, T Dayeh, P Volkov, T Elgzyri, E Hall, E Nilsson, BT Yang, ...
Diabetes 61 (12), 3322-3332, 2012
4442012
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin
KL Egerod, MS Engelstoft, KV Grunddal, MK Nøhr, A Secher, I Sakata, ...
Endocrinology 153 (12), 5782-5795, 2012
3372012
Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes
AS Axelsson, E Tubbs, B Mecham, S Chacko, HA Nenonen, Y Tang, ...
Science translational medicine 9 (394), eaah4477, 2017
3082017
Orexin loss in Huntington's disease
Å Petersén, J Gil, MLC Maat-Schieman, M Björkqvist, H Tanila, IM Araujo, ...
Human molecular genetics 14 (1), 39-47, 2005
3082005
Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells
N Wierup, S Yang, RJ McEvilly, H Mulder, F Sundler
Journal of Histochemistry & Cytochemistry 52 (3), 301-310, 2004
2972004
Increased melatonin signaling is a risk factor for type 2 diabetes
T Tuomi, CLF Nagorny, P Singh, H Bennet, Q Yu, I Alenkvist, B Isomaa, ...
Cell metabolism 23 (6), 1067-1077, 2016
2512016
TCF7L2 is a master regulator of insulin production and processing
Y Zhou, SY Park, J Su, K Bailey, E Ottosson-Laakso, L Shcherbina, ...
Human molecular genetics 23 (24), 6419-6431, 2014
2372014
A Central Role for GRB10 in Regulation of Islet Function in Man
I Prokopenko, W Poon, R Maegi, R Prasad B, SA Salehi, P Almgren, ...
PLoS genetics 10 (4), e1004235, 2014
1842014
Capsaicin‐sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type …
DX Gram, B Ahrén, I Nagy, UB Olsen, CL Brand, F Sundler, R Tabanera, ...
European Journal of Neuroscience 25 (1), 213-223, 2007
1832007
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient β-cell mass and exocytosis
M Björkqvist, M Fex, E Renström, N Wierup, Å Petersén, J Gil, K Bacos, ...
Human molecular genetics 14 (5), 565-574, 2005
1742005
The islet ghrelin cell
N Wierup, F Sundler, RS Heller
Journal of molecular endocrinology 52 (1), R35-R49, 2014
1612014
Increased metabolism in the R6/2 mouse model of Huntington’s disease
JMM van der Burg, K Bacos, NI Wood, A Lindqvist, N Wierup, B Woodman, ...
Neurobiology of disease 29 (1), 41-51, 2008
1542008
CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight
N Wierup, WG Richards, AW Bannon, MJ Kuhar, B Ahrén, F Sundler
Regulatory peptides 129 (1-3), 203-211, 2005
1292005
Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects
M Riva, MD Nitert, U Voss, R Sathanoori, A Lindqvist, C Ling, N Wierup
Cell and tissue research 346, 393-405, 2011
1182011
Cocaine‐and amphetamine‐regulated transcript: distribution and function in rat gastrointestinal tract
E Ekblad, M Kuhar, N Wierup, F Sundler
Neurogastroenterology & Motility 15 (5), 545-557, 2003
1172003
Link between GIP and osteopontin in adipose tissue and insulin resistance
E Ahlqvist, P Osmark, T Kuulasmaa, K Pilgaard, B Omar, C Brøns, ...
Diabetes 62 (6), 2088-2094, 2013
1162013
Apelin is a novel islet peptide
C Ringström, MD Nitert, H Bennet, M Fex, P Valet, JF Rehfeld, ...
Regulatory peptides 162 (1-3), 44-51, 2010
1122010
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