| DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer SM Sureban, R May, D Qu, N Weygant, P Chandrakesan, N Ali, ... PloS one 8 (9), e73940, 2013 | 154 | 2013 |
| Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1 N Weygant, D Qu, WL Berry, R May, P Chandrakesan, DB Owen, ... Molecular cancer 13, 1-14, 2014 | 123 | 2014 |
| XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism SM Sureban, R May, N Weygant, D Qu, P Chandrakesan, ... Cancer letters 351 (1), 151-161, 2014 | 123 | 2014 |
| Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells P Chandrakesan, J Yao, D Qu, R May, N Weygant, Y Ge, N Ali, ... Molecular Cancer 16, 1-14, 2017 | 107 | 2017 |
| DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma N Weygant, D Qu, R May, RM Tierney, WL Berry, L Zhao, S Agarwal, ... Oncotarget 6 (4), 2193, 2015 | 92 | 2015 |
| Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury R May, D Qu, N Weygant, P Chandrakesan, N Ali, SA Lightfoot, L Li, ... Stem cells 32 (3), 822-827, 2014 | 88 | 2014 |
| Identification of the putative intestinal stem cell marker doublecortin and CaM kinase‐like‐1 in Barrett's esophagus and esophageal adenocarcinoma KJ Vega, R May, SM Sureban, SA Lightfoot, D Qu, A Reed, N Weygant, ... Journal of gastroenterology and hepatology 27 (4), 773-780, 2012 | 85 | 2012 |
| DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition P Chandrakesan, N Weygant, R May, D Qu, HR Chinthalapally, ... Oncotarget 5 (19), 9269, 2014 | 83 | 2014 |
| Ablation of doublecortin-like kinase 1 in the colonic epithelium exacerbates dextran sulfate sodium-induced colitis D Qu, N Weygant, R May, P Chandrakesan, M Madhoun, N Ali, ... PLoS One 10 (8), e0134212, 2015 | 70 | 2015 |
| Cancer stem cell marker DCLK1 correlates with tumorigenic immune infiltrates in the colon and gastric adenocarcinoma microenvironments X Wu, D Qu, N Weygant, J Peng, CW Houchen Cancers 12 (2), 274, 2020 | 64 | 2020 |
| Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation Z Wang, G Su, Z Dai, M Meng, H Zhang, F Fan, Z Liu, L Zhang, N Weygant, ... Cell proliferation 54 (3), e12988, 2021 | 58 | 2021 |
| Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism SM Sureban, MF Madhoun, R May, D Qu, N Ali, J Fazili, N Weygant, ... Oncotarget 6 (35), 37200, 2015 | 58 | 2015 |
| Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer Y Ge, N Weygant, D Qu, R May, WL Berry, J Yao, P Chandrakesan, ... International journal of cancer 143 (5), 1162-1175, 2018 | 56 | 2018 |
| Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells D Qu, J Johnson, P Chandrakesan, N Weygant, R May, N Aiello, A Rhim, ... PloS one 10 (2), e0118933, 2015 | 55 | 2015 |
| Regulatory roles of Dclk1 in epithelial mesenchymal transition and cancer stem cells P Chandrakesan, J Panneerselvam, D Qu, N Weygant, R May, MS Bronze, ... Journal of carcinogenesis & mutagenesis 7 (2), 2016 | 50 | 2016 |
| Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal P Chandrakesan, R May, D Qu, N Weygant, VE Taylor, JD Li, N Ali, ... Oncotarget 6 (31), 30876, 2015 | 47 | 2015 |
| Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury P Chandrakesan, R May, N Weygant, D Qu, WL Berry, SM Sureban, N Ali, ... Scientific reports 6 (1), 37667, 2016 | 46 | 2016 |
| Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism N Ali, H Allam, T Bader, R May, KM Basalingappa, WL Berry, ... PloS one 8 (11), e80304, 2013 | 43 | 2013 |
| Dietary pectin increases intestinal crypt stem cell survival following radiation injury SM Sureban, R May, D Qu, P Chandrakesan, N Weygant, N Ali, ... PloS one 10 (8), e0135561, 2015 | 41 | 2015 |
| RAS/BRAF circulating tumor DNA mutations as a predictor of response to first-line chemotherapy in metastatic colorectal cancer patients J Yao, W Zang, Y Ge, N Weygant, P Yu, L Li, G Rao, Z Jiang, R Yan, L He, ... Canadian Journal of Gastroenterology and Hepatology 2018, 2018 | 38 | 2018 |
Parthasarathy ChandrakesanDirector Research & Development, Wild Earth, Former Associate Professor, Member of Stepenson CancerVerified email at wildearth.com
