The potential of arsenic trioxide in the treatment of malignant disease: past, present, and future AM Evens, MS Tallman, RB Gartenhaus Leukemia research 28 (9), 891-900, 2004 | 244 | 2004 |
Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism P Phatak, JC Cookson, F Dai, V Smith, RB Gartenhaus, MFG Stevens, ... British journal of cancer 96 (8), 1223-1233, 2007 | 225 | 2007 |
Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia … ZN Berneman, RB Gartenhaus, MS Reitz Jr, WA Blattner, A Manns, ... Proceedings of the National Academy of Sciences 89 (7), 3005-3009, 1992 | 182 | 1992 |
MSRE-PCR for analysis of gene-specific DNA methylation AA Melnikov, RB Gartenhaus, AS Levenson, NA Motchoulskaia, ... Nucleic acids research 33 (10), e93-e93, 2005 | 145 | 2005 |
Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype K Mazan-Mamczarz, PR Hagner, S Corl, S Srikantan, WH Wood, ... Oncogene 27 (47), 6151-6163, 2008 | 135 | 2008 |
PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21 F Hu, RB Gartenhaus, D Eichberg, Z Liu, HB Fang, AP Rapoport Oncogene 29 (40), 5464-5474, 2010 | 123 | 2010 |
Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development K Mazan-Mamczarz, XF Zhao, B Dai, JJ Steinhardt, RJ Peroutka, KL Berk, ... PLoS genetics 10 (1), e1004105, 2014 | 111 | 2014 |
Arsenic trioxide cytotoxicity in steroid and chemotherapy-resistant myeloma cell lines: enhancement of apoptosis by manipulation of cellular redox state RB Gartenhaus, SN Prachand, M Paniaqua, Y Li, LI Gordon Clinical cancer research 8 (2), 566-572, 2002 | 110 | 2002 |
Induction of the WAF1/CIP1 protein and apoptosis in human T-cell leukemia virus type I-transformed lymphocytes after treatment with adriamycin by using a p53-independent pathway. RB Gartenhaus, P Wang, P Hoffmann Proceedings of the National Academy of Sciences 93 (1), 265-268, 1996 | 109 | 1996 |
Targeting the translational machinery as a novel treatment strategy for hematologic malignancies PR Hagner, A Schneider, RB Gartenhaus Blood, The Journal of the American Society of Hematology 115 (11), 2127-2135, 2010 | 103 | 2010 |
Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice A Heredia, N Le, RB Gartenhaus, E Sausville, S Medina-Moreno, ... Proceedings of the National Academy of Sciences 112 (30), 9412-9417, 2015 | 96 | 2015 |
A phase II study of DT fusion protein denileukin diftitox in patients with fludarabine-refractory chronic lymphocytic leukemia AE Frankel, DR Fleming, PD Hall, BL Powell, JH Black, C Leftwich, ... Clinical cancer research 9 (10), 3555-3561, 2003 | 95 | 2003 |
MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL AL Landon, PA Muniandy, AC Shetty, E Lehrmann, L Volpon, S Houng, ... Nature communications 5 (1), 5413, 2014 | 93 | 2014 |
Motexafin gadolinium generates reactive oxygen species and induces apoptosis in sensitive and highly resistant multiple myeloma cells AM Evens, P Lecane, D Magda, S Prachand, S Singhal, J Nelson, ... Blood 105 (3), 1265-1273, 2005 | 93 | 2005 |
Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies Z Li, K Younger, R Gartenhaus, AM Joseph, F Hu, MR Baer, P Brown, ... The Journal of clinical investigation 125 (3), 1081-1097, 2015 | 85 | 2015 |
The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation MI Vitolo, IE Anglin, WM Mahoney, KJ Renoud, RB Gartenhaus, ... Cancer biology & therapy 6 (6), 856-863, 2007 | 84 | 2007 |
Fatty acid synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL B Kapadia, NM Nanaji, K Bhalla, B Bhandary, R Lapidus, A Beheshti, ... Nature communications 9 (1), 829, 2018 | 79 | 2018 |
A Novel Candidate Oncogene, MCT-1, Is Involved in Cell Cycle Progression M Prosniak, J Dierov, K Okami, B Tilton, B Jameson, BE Sawaya, ... Cancer research 58 (19), 4233-4237, 1998 | 74 | 1998 |
Mutator phenotype in a subset of chronic lymphocytic leukemia R Gartenhaus, MM Johns III, P Wang, K Rai, D Sidransky Blood 87 (1), 38-41, 1996 | 74 | 1996 |
Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era C Nabhan, RB Gartenhaus, MS Tallman Leukemia research 28 (5), 429-442, 2004 | 70 | 2004 |