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Atsushi Matsuzawa
Atsushi Matsuzawa
Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University
Verified email at m.tohoku.ac.jp
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Year
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
H Nishitoh, A Matsuzawa, K Tobiume, K Saegusa, K Takeda, K Inoue, ...
Genes & development 16 (11), 1345-1355, 2002
16512002
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
K Tobiume, A Matsuzawa, T Takahashi, H Nishitoh, K Morita, K Takeda, ...
EMBO reports, 2001
14292001
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
A Matsuzawa, K Saegusa, T Noguchi, C Sadamitsu, H Nishitoh, S Nagai, ...
Nature immunology 6 (6), 587-592, 2005
7532005
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling
S Vallabhapurapu, A Matsuzawa, WZ Zhang, PH Tseng, JJ Keats, ...
Nature immunology 9 (12), 1364-1370, 2008
7282008
ALS-linked mutant SOD1 induces ER stress-and ASK1-dependent motor neuron death by targeting Derlin-1
H Nishitoh, H Kadowaki, A Nagai, T Maruyama, T Yokota, H Fukutomi, ...
Genes & development 22 (11), 1451-1464, 2008
6082008
Hepatocyte necrosis induced by oxidative stress and IL-1α release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis
T Sakurai, G He, A Matsuzawa, GY Yu, S Maeda, G Hardiman, M Karin
Cancer cell 14 (2), 156-165, 2008
5792008
Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling
A Matsuzawa, H Ichijo
Biochimica et Biophysica Acta (BBA)-General Subjects 1780 (11), 1325-1336, 2008
5692008
Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation
H Kadowaki, H Nishitoh, F Urano, C Sadamitsu, A Matsuzawa, K Takeda, ...
Cell Death & Differentiation 12 (1), 19-24, 2005
4882005
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines
PH Tseng, A Matsuzawa, W Zhang, T Mino, DAA Vignali, M Karin
Nature immunology 11 (1), 70-75, 2010
4822010
The ASK1-MAP kinase cascades in mammalian stress response
J Matsukawa, A Matsuzawa, K Takeda, H Ichijo
The Journal of biochemistry 136 (3), 261-265, 2004
4192004
Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation
T Hatai, A Matsuzawa, S Inoshita, Y Mochida, T Kuroda, K Sakamaki, ...
Journal of Biological Chemistry 275 (34), 26576-26581, 2000
4112000
Stress-responsive protein kinases in redox-regulated apoptosis signaling
A Matsuzawa, H Ichijo
Antioxidants & redox signaling 7 (3-4), 472-481, 2005
3542005
Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
G Fujino, T Noguchi, A Matsuzawa, S Yamauchi, M Saitoh, K Takeda, ...
Molecular and cellular biology 27 (23), 8152-8163, 2007
3352007
Physiological roles of ASK1-mediated signal transduction in oxidative stress-and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice
A Matsuzawa, H Nishitoh, K Tobiume, K Takeda, H Ichijo
Antioxidants and Redox Signaling 4 (3), 415-425, 2002
3062002
Roles of MAPKKK ASK1 in stress-induced cell death
K Takeda, A Matsuzawa, H Nishitoh, H Ichijo
Cell structure and function 28 (1), 23-29, 2003
2902003
Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II–induced cardiac hypertrophy and remodeling
Y Izumiya, S Kim, Y Izumi, K Yoshida, M Yoshiyama, A Matsuzawa, ...
Circulation Research 93 (9), 874-883, 2003
2692003
Essential cytoplasmic translocation of a cytokine receptor–assembled signaling complex
A Matsuzawa, PH Tseng, S Vallabhapurapu, JL Luo, W Zhang, H Wang, ...
Science 321 (5889), 663-668, 2008
2662008
Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced …
T Noguchi, K Takeda, A Matsuzawa, K Saegusa, H Nakano, J Gohda, ...
Journal of Biological Chemistry 280 (44), 37033-37040, 2005
2572005
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis
O Yamaguchi, T Watanabe, K Nishida, K Kashiwase, Y Higuchi, T Takeda, ...
The Journal of clinical investigation 114 (7), 937-943, 2004
2422004
Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1
A Matsuzawa, H Ichijo
The journal of biochemistry 130 (1), 1-8, 2001
2242001
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Articles 1–20