The rheumatoid arthritis-associated citrullinome R Tilvawala, SH Nguyen, AJ Maurais, VV Nemmara, M Nagar, ... Cell chemical biology 25 (6), 691-704. e6, 2018 | 179 | 2018 |
Development of a selective inhibitor of protein arginine deiminase 2 A Muth, V Subramanian, E Beaumont, M Nagar, P Kerry, P McEwan, ... Journal of medicinal chemistry 60 (7), 3198-3211, 2017 | 73 | 2017 |
Calcium regulates the nuclear localization of protein arginine deiminase 2 L Zheng, M Nagar, AJ Maurais, DJ Slade, SS Parelkar, SA Coonrod, ... Biochemistry 58 (27), 3042-3056, 2019 | 37 | 2019 |
Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron AD Lietzan, M Nagar, EA Pellmann, JR Bourque, SL Bearne, ... Biochemistry 51 (6), 1160-1170, 2012 | 34 | 2012 |
Potent inhibition of mandelate racemase by a fluorinated substrate-product analogue with a novel binding mode M Nagar, AD Lietzan, M St. Maurice, SL Bearne Biochemistry 53 (7), 1169-1178, 2014 | 28 | 2014 |
Inhibition of serine and proline racemases by substrate-product analogues M Harty, M Nagar, L Atkinson, CM LeGay, DJ Derksen, SL Bearne Bioorganic & Medicinal Chemistry Letters 24 (1), 390-393, 2014 | 26 | 2014 |
Redefining the minimal substrate tolerance of mandelate racemase. Racemization of trifluorolactate M Nagar, A Narmandakh, Y Khalak, SL Bearne Biochemistry 50 (41), 8846-8852, 2011 | 23 | 2011 |
Photochemical control of protein arginine deiminase (PAD) activity S Mondal, SS Parelkar, M Nagar, PR Thompson ACS chemical biology 13 (4), 1057-1065, 2018 | 21 | 2018 |
Thioredoxin modulates protein arginine deiminase 4 (PAD4)-catalyzed citrullination M Nagar, R Tilvawala, PR Thompson Frontiers in immunology 10, 413103, 2019 | 19 | 2019 |
An Additional Role for the Brønsted Acid–Base Catalysts of Mandelate Racemase in Transition State Stabilization M Nagar, SL Bearne Biochemistry 54 (44), 6743-6752, 2015 | 15 | 2015 |
Inactivation of mandelate racemase by 3-hydroxypyruvate reveals a potential mechanistic link between enzyme superfamilies M Nagar, BN Wyatt, M St. Maurice, SL Bearne Biochemistry 54 (17), 2747-2757, 2015 | 13 | 2015 |
Altering the Y137-K164-K166 triad of mandelate racemase and its effect on the observed pKa of the Brønsted base catalysts CM Fetter, ZA Morrison, M Nagar, CD Douglas, SL Bearne Archives of biochemistry and biophysics 666, 116-126, 2019 | 10 | 2019 |
Altering the binding determinant on the interdigitating loop of mandelate racemase shifts specificity towards that of d-tartrate dehydratase M Nagar, JA Hayden, E Sagey, G Worthen, M Park, AN Sharma, ... Archives of Biochemistry and Biophysics 718, 109119, 2022 | 3 | 2022 |
A platform for chemical modification of mandelate racemase: characterization of the C92S/C264S and γ-thialysine 166 variants M Nagar, H Kumar, SL Bearne Protein Engineering, Design and Selection 31 (4), 135-145, 2018 | 2 | 2018 |
MANDELATE RACEMASE: INSIGHTS INTO SUBSTRATE TOLERANCE, NOVEL INHIBITOR-BINDING MODES, AND THE ROLE OF BINDING DETERMINANTS M Nagar | | 2016 |