Intermittent fasting promotes white adipose browning and decreases obesity by shaping the gut microbiota G Li, C Xie, S Lu, RG Nichols, Y Tian, L Li, D Patel, Y Ma, CN Brocker, ... Cell metabolism 26 (4), 672-685. e4, 2017 | 642 | 2017 |
Herbal drug discovery for the treatment of nonalcoholic fatty liver disease T Yan, N Yan, P Wang, Y Xia, H Hao, G Wang, FJ Gonzalez Acta Pharmaceutica Sinica B 10 (1), 3-18, 2020 | 160 | 2020 |
Rutaecarpine inhibits KEAP1-NRF2 interaction to activate NRF2 and ameliorate dextran sulfate sodium-induced colitis Y Zhang, T Yan, D Sun, C Xie, T Wang, X Liu, J Wang, Q Wang, Y Luo, ... Free Radical Biology and Medicine 148, 33-41, 2020 | 86 | 2020 |
Glycyrrhizin alleviates nonalcoholic steatohepatitis via modulating bile acids and meta-inflammation T Yan, H Wang, L Cao, Q Wang, S Takahashi, T Yagai, G Li, KW Krausz, ... Drug Metabolism and Disposition 46 (9), 1310-1319, 2018 | 76 | 2018 |
Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice CN Brocker, DP Patel, TJ Velenosi, D Kim, T Yan, J Yue, G Li, KW Krausz, ... Journal of lipid research 59 (11), 2140-2152, 2018 | 65 | 2018 |
Glycyrrhizin protects against acetaminophen-induced acute liver injury via alleviating tumor necrosis factor α–mediated apoptosis T Yan, H Wang, M Zhao, T Yagai, Y Chai, KW Krausz, C Xie, X Cheng, ... Drug Metabolism and Disposition 44 (5), 720-731, 2016 | 61 | 2016 |
Ginsenosides regulate PXR/NF-κB signaling and attenuate dextran sulfate sodium–induced colitis J Zhang, L Cao, H Wang, X Cheng, L Wang, L Zhu, T Yan, Y Xie, Y Wu, ... Drug Metabolism and Disposition 43 (8), 1181-1189, 2015 | 55 | 2015 |
Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis T Yan, Y Luo, N Yan, K Hamada, N Zhao, Y Xia, P Wang, C Zhao, D Qi, ... Hepatology 77 (1), 239-255, 2023 | 43 | 2023 |
Role of farnesoid X receptor and bile acids in hepatic tumor development S Takahashi, N Tanaka, T Fukami, C Xie, T Yagai, D Kim, TJ Velenosi, ... Hepatology communications 2 (12), 1567-1582, 2018 | 43 | 2018 |
Metabolic profile, enzyme kinetics, and reaction phenotyping of β-lapachone metabolism in human liver and intestine in vitro X Cheng, F Liu, T Yan, X Zhou, L Wu, K Liao, G Wang, H Hao Molecular pharmaceutics 9 (12), 3476-3485, 2012 | 39 | 2012 |
Noncanonical farnesoid X receptor signaling inhibits apoptosis and impedes liver fibrosis H Wang, C Ge, J Zhou, Y Guo, S Cui, N Huang, T Yan, L Cao, Y Che, ... EBioMedicine 37, 322-333, 2018 | 36 | 2018 |
The pathophysiological function of non-gastrointestinal farnesoid X receptor N Yan, T Yan, Y Xia, H Hao, G Wang, FJ Gonzalez Pharmacology & therapeutics 226, 107867, 2021 | 35 | 2021 |
Comparison of bioactive components and pharmacological activities of ophiopogon japonicas extracts from different geographical origins M Zhao, W Xu, H Shen, P Shen, J Zhang, D Wang, H Xu, H Wang, T Yan, ... Journal of pharmaceutical and biomedical analysis 138, 134-141, 2017 | 31 | 2017 |
Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha G Li, CN Brocker, T Yan, C Xie, KW Krausz, R Xiang, FJ Gonzalez Molecular metabolism 7, 80-89, 2018 | 28 | 2018 |
Silybin alleviates hepatic lipid accumulation in methionine-choline deficient diet-induced nonalcoholic fatty liver disease in mice via peroxisome proliferator-activated receptor α CUI Shuang, PAN Xiao-Jie, GE Chao-Liang, GUO Yi-Tong, PF Zhang, ... Chinese Journal of Natural Medicines 19 (6), 401-411, 2021 | 27 | 2021 |
Structure-activity relationships of the main bioactive constituents of euodia rutaecarpa on aryl hydrocarbon receptor activation and associated bile acid homeostasis Y Zhang, T Yan, D Sun, C Xie, Y Zheng, L Zhang, T Yagai, KW Krausz, ... Drug Metabolism and Disposition 46 (7), 1030-1040, 2018 | 26 | 2018 |
Withaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3 Y Xia, P Wang, N Yan, FJ Gonzalez, T Yan Cell death & disease 12 (2), 174, 2021 | 24 | 2021 |
Withaferin A improves nonalcoholic steatohepatitis in mice DP Patel, T Yan, D Kim, HB Dias, KW Krausz, S Kimura, FJ Gonzalez Journal of Pharmacology and Experimental Therapeutics 371 (2), 360-374, 2019 | 21 | 2019 |
Hepatic peroxisome proliferator‐activated receptor alpha mediates the major metabolic effects of Wy‐14643 G Li, CN Brocker, C Xie, T Yan, A Noguchi, KW Krausz, R Xiang, ... Journal of gastroenterology and hepatology 33 (5), 1138-1145, 2018 | 21 | 2018 |
Mechanism-Based Inhibitory and Peroxisome Proliferator-Activated Receptor α–Dependent Modulating Effects of Silybin on Principal Hepatic Drug-Metabolizing Enzymes H Wang, T Yan, Y Xie, M Zhao, Y Che, J Zhang, H Liu, L Cao, X Cheng, ... Drug Metabolism and Disposition 43 (4), 444-454, 2015 | 21 | 2015 |