Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic? RG Morgan, E Mortensson, AC Williams British journal of cancer 118 (11), 1410-1418, 2018 | 108 | 2018 |
LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma GC Vieira, S Chockalingam, Z Melegh, A Greenhough, S Malik, ... Oncotarget 6 (37), 40053, 2015 | 79 | 2015 |
The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts J Zabkiewicz, L Pearn, RK Hills, RG Morgan, A Tonks, AK Burnett, ... Haematologica 99 (5), 858, 2014 | 72 | 2014 |
γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin RG Morgan, L Pearn, K Liddiard, SL Pumford, AK Burnett, A Tonks, ... Leukemia 27 (2), 336-343, 2013 | 65 | 2013 |
Factors Affecting the Nuclear Localization of β‐Catenin in Normal and Malignant Tissue RG Morgan, J Ridsdale, A Tonks, RL Darley Journal of cellular biochemistry 115 (8), 1351-1361, 2014 | 63 | 2014 |
LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells RG Morgan, J Ridsdale, M Payne, KJ Heesom, MC Wilson, A Davidson, ... Haematologica 104 (7), 1365, 2019 | 54 | 2019 |
Optimized delivery of siRNA into 3D tumor spheroid cultures in situ RG Morgan, AC Chambers, DN Legge, SJ Coles, A Greenhough, ... Scientific reports 8 (1), 7952, 2018 | 33 | 2018 |
Preliminary evidence of reductive stress in human cytotoxic T cells following exercise AJ Wadley, A Holliday, RG Morgan, KJ Heesom, S Aldred, DM Peters, ... Journal of applied physiology 125 (2), 586-595, 2018 | 19 | 2018 |
Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting … RG Morgan, E Molnar, RF Jones, TJ Collard, JD Lane, A Greenhough, ... British journal of cancer 112 (4), 714-719, 2015 | 16 | 2015 |
LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity RG Morgan, E Mortensson, DN Legge, B Gupta, TJ Collard, ... British journal of cancer 118 (4), 558-565, 2018 | 15 | 2018 |
Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells JB Menendez-Gonzalez, S Sinnadurai, A Gibbs, L Thomas, ... Scientific Reports 9 (1), 12212, 2019 | 13 | 2019 |
Targeting β-catenin in acute myeloid leukaemia: past, present, and future perspectives M Wagstaff, B Coke, GR Hodgkiss, RG Morgan Bioscience Reports 42 (4), BSR20211841, 2022 | 9 | 2022 |
Crosstalk between b-catenin and WT1 signaling activity in acute myeloid leukemia M Wagstaff, O Tsaponina, G Caalim, H Greenfield, L Milton-Harris, ... Haematologica 108 (1), 283, 2023 | 5 | 2023 |
Epstein-Barr Virus Genome Deletions in Epstein-Barr Virus-Positive T/NK Cell Lymphoproliferative Diseases W Wongwiwat, B Fournier, I Bassano, A Bayoumy, C Elgueta Karstegl, ... Journal of Virology 96 (12), e00394-22, 2022 | 5 | 2022 |
BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination C Parker, AC Chambers, DJ Flanagan, JWY Ho, TJ Collard, G Ngo, ... DNA repair 115, 103331, 2022 | 4 | 2022 |
Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers AJ Wadley, RG Morgan, KJ Heesom, PS Hole, SJ Coles MethodsX 5, 1473-1483, 2018 | 2 | 2018 |
γ-Catenin is expressed throughout normal human hematopoietic development and is required for normal PU. 1-dependent monocyte differentiation RG Morgan, K Liddiard, L Pearn, SL Pumford, AK Burnett, RL Darley, ... leukemia 27 (10), 2096-2100, 2013 | 2 | 2013 |
PDK1 overexpression in acute myeloid leukemia; clinical significance and potential as a therapeutic target J Zabkiewicz, L Pearn, R Hills, G Morgan, A Burnett, A Tonks, RL Darley Blood 116 (21), 2162, 2010 | 2 | 2010 |
Using flow cytometry to detect and measure intracellular thiol redox status in viable T cells from heterogeneous populations AJ Wadley, RG Morgan, RL Darley, PS Hole, SJ Coles Redox-Mediated Signal Transduction: Methods and Protocols, 53-70, 2019 | 1 | 2019 |
A β-catenin: MSI2 axis regulates the expression of LEF1 and subsequent human haematopoietic stem/progenitor cell proliferation RG Morgan, M Wagstaff, DT Nguyen, A Blair, BP Towler, SF Newbury bioRxiv, 2024.01. 28.577638, 2024 | | 2024 |