Domain combinations in archaeal, eubacterial and eukaryotic proteomes G Apic, J Gough, SA Teichmann Journal of molecular biology 310 (2), 311-325, 2001 | 607 | 2001 |
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing Nature genetics 44 (12), 1316-1320, 2012 | 504 | 2012 |
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms K Boldt, J Van Reeuwijk, Q Lu, K Koutroumpas, TMT Nguyen, Y Texier, ... Nature communications 7 (1), 11491, 2016 | 257 | 2016 |
An insight into domain combinations G Apic, J Gough, SA Teichmann ISMB (Supplement of Bioinformatics), 83-89, 2001 | 157 | 2001 |
Illuminating drug discovery with biological pathways G Apic, T Ignjatovic, S Boyer, RB Russell FEBS letters 579 (8), 1872-1877, 2005 | 152 | 2005 |
Multi-domain protein families and domain pairs: comparison with known structures and a random model of domain recombination G Apic, W Huber, SA Teichmann Journal of structural and functional genomics 4, 67-78, 2003 | 111 | 2003 |
Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions MJ Betts, Q Lu, YY Jiang, A Drusko, O Wichmann, M Utz, ... Nucleic acids research 43 (2), e10-e10, 2015 | 96 | 2015 |
Toxicology ontology perspectives B Hardy, G Apic, P Carthew, D Clark, D Cook, I Dix, S Escher, J Hastings, ... ALTEX-Alternatives to animal experimentation 29 (2), 139-156, 2012 | 51 | 2012 |
A toxicology ontology roadmap B Hardy, G Apic, P Carthew, D Clark, D Cook, I Dix, S Escher, J Hastings, ... ALTEX-Alternatives to animal experimentation 29 (2), 129-137, 2012 | 39 | 2012 |
Combinations of protein-chemical complex structures reveal new targets for established drugs OV Kalinina, O Wichmann, G Apic, RB Russell PLOS computational biology 7 (5), e1002043, 2011 | 37 | 2011 |
Content disputes in Wikipedia reflect geopolitical instability G Apic, MJ Betts, RB Russell PloS one 6 (6), e20902, 2011 | 36 | 2011 |
Next generation protein structure predictions and genetic variant interpretation GD Diwan, JC Gonzalez-Sanchez, G Apic, RB Russell Journal of molecular biology 433 (20), 167180, 2021 | 34 | 2021 |
Domain recombination: a workhorse for evolutionary innovation G Apic, RB Russell Science signaling 3 (139), pe30-pe30, 2010 | 30 | 2010 |
Insights into cancer severity from biomolecular interaction mechanisms F Raimondi, G Singh, MJ Betts, G Apic, R Vukotic, P Andreone, L Stein, ... Scientific reports 6 (1), 34490, 2016 | 25 | 2016 |
ProtChemSI: a network of protein–chemical structural interactions OV Kalinina, O Wichmann, G Apic, RB Russell Nucleic acids research 40 (D1), D549-D553, 2012 | 19 | 2012 |
Emerging trends in the field of inflammation and proteinopathy in ALS/FTD spectrum disorder F De Marchi, T Franjkic, P Schito, T Russo, J Nimac, AA Chami, A Mele, ... Biomedicines 11 (6), 1599, 2023 | 17 | 2023 |
Pathway analysis for drug discovery: computational infrastructure and applications S Ekins John Wiley & Sons, 2008 | 15 | 2008 |
The precision toxicology initiative PrecisionTox Consortium Toxicology letters 383, 33-42, 2023 | 10 | 2023 |
Never-homozygous genetic variants in healthy populations are potential recessive disease candidates T Schmenger, GD Diwan, G Singh, G Apic, RB Russell NPJ Genomic Medicine 7 (1), 54, 2022 | 7 | 2022 |
Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas C Lopez, N Schleussner, SH Bernhart, K Kleinheinz, S Sungalee, ... Haematologica 108 (2), 543, 2022 | 5 | 2022 |