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Saffie Mohran
Saffie Mohran
Other namesSaffie E. Mohran
Verified email at uw.edu
Title
Cited by
Cited by
Year
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin
JD Powers, CC Yuan, KJ McCabe, JD Murray, MC Childers, GV Flint, ...
Proceedings of the National Academy of Sciences 116 (23), 11502-11507, 2019
372019
Danicamtiv increases myosin recruitment and alters cross-bridge cycling in cardiac muscle
KB Kooiker, S Mohran, KL Turner, W Ma, A Martinson, G Flint, L Qi, C Gao, ...
Circulation Research 133 (5), 430-443, 2023
8*2023
Doppler assessment of diastolic function reflect the severity of injury in rats with chronic heart failure
P Sanchez, JJ Lancaster, K Weigand, SAEE Mohran, S Goldman, ...
Journal of Cardiac Failure 23 (10), 753-761, 2017
52017
Epicardially placed bioengineered cardiomyocyte xenograft in immune-competent rat model of heart failure
IR Chinyere, P Bradley, J Uhlorn, J Eason, S Mohran, GG Repetti, ...
Stem cells international 2021, 1-9, 2021
42021
The biochemically defined super relaxed state of myosin—a paradox
S Mohran, K Kooiker, M Mahoney-Schaefer, C Mandrycky, K Kao, AY Tu, ...
Journal of Biological Chemistry 300 (1), 2024
32024
Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration
S Lee, AS Vander Roest, CA Blair, K Kao, SB Bremner, MC Childers, ...
Proceedings of the National Academy of Sciences 121 (19), e2318413121, 2024
1*2024
MYBPC3-c. 772G> a mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic …
S Sonette, S Mohran, LRJ Bailey, TS McMillen, KB Kooiker, NB Wood, ...
Journal of Molecular and Cellular Cardiology, 2024
12024
Measuring the Contractile Kinetics of Isolated Myofibrils from Human-Induced Pluripotent Stem Cell Derived Cardiomyocyte (hiPSC-CM) Models of Cardiomyopathy
S Mohran, S Steczina, C Mandrycky, K Kao, M Regnier
Familial Cardiomyopathies: Methods and Protocols, 213-233, 2023
12023
Structure-Function Investigation of the E258K-Mybpc3 Mutation in HCM Patient-Derived Cardiomyocytes
S Steczina, JM Pioner, S Mohran, M Langione, G Vitale, B Scellini, ...
Biophysical Journal 120 (3), 253a-254a, 2021
12021
Cardiac grafts engineered from human induced pluripotent stem cell ventricular pure or heterogeneous cardiomyocytes display synchronous and spontaneous contraction and reduce …
JJ Lancaster, J Koevary, IR Chinyere, SAE Mohran, EB Juneman, ...
Circulation Research 121 (suppl_1), A344-A344, 2017
12017
The effect of small molecule myosin inhibitors on ATP cycling in porcine cardiac muscle using stopped-flow spectroscopy and in vitro motility
M Mahoney-Schaefer, KB Kooiker, S Mohran, GV Flint, M Regnier, ...
Biophysical Journal 123 (3), 266a-267a, 2024
2024
Mechanisms of myosin, myofibril, and cardiomyocyte dysfunction with the MYH7 R403Q mutation in porcine ventricle muscle
S Mohran, S Steczina, KB Kooiker, T McMillen, C Mandrycky, MC Childers, ...
Biophysical Journal 123 (3), 267a, 2024
2024
Decoupling calcium-dependent thin-filament activation from thick-filament activation in porcine myocardium
S Mohran, C Mandrycky, A Tu, T McMillen, KB Kooiker, W Qian, TC Irving, ...
Biophysical Journal 123 (3), 520a, 2024
2024
MYH3 mutations associated with distal arthrogryposis alter the contractility and myosin isoform switching of hiPSC-derived skeletal muscle
C Mandrycky, S Mohran, MC Childers, SM Luttrell, E Choi, K Buckingham, ...
Biophysical Journal 123 (3), 275a, 2024
2024
A molecular-scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation
KY Kao, MC Childers, S Mohran, M Regnier
Biophysical Journal 123 (3), 267a, 2024
2024
MYBPC3-c. 772G> A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient-induced stem cell-derived cardiomyocyte model of hypertrophic …
S Steczina, S Mohran, L Bailey, T McMillen, KB Kooiker, NB Wood, ...
Biophysical Journal 123 (3), 318a-319a, 2024
2024
2-Deoxy-ATP reduces the cardiac depressive effect of acidosis
MA Redd, TS McMillen, MK Woodward, S Mohran, KB Kooiker, GV Flint, ...
Biophysical Journal 123 (3), 403a-404a, 2024
2024
The effect of small molecule myosin modulators on ATP turnover in pig cardiac HMM using stopped flow spectroscopy
KB Kooiker, S Mohran, M Mahoney-Schaefer, J Freeman, MA Geeves, ...
Biophysical Journal 122 (3), 121a-122a, 2023
2023
The β-myosin G256E mutation impairs relaxation by altering transducer stiffness
MC Childers, KY Kao, S Mohran, M Regnier
Biophysical Journal 122 (3), 402a, 2023
2023
Muscle length alters activation kinetics in fast-twitch edl muscle and relaxation kinetics in slow-twitch soleus muscle
S Mohran, HM Gong, M Regnier, TC Irving, W Ma
Biophysical Journal 122 (3), 28a, 2023
2023
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