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Lianfeng Wu
Lianfeng Wu
Westlake University
Verified email at westlake.edu.cn - Homepage
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Year
An ancient, unified mechanism for metformin growth inhibition in C. elegans and cancer
L Wu, B Zhou, N Oshiro-Rapley, M Li, JA Paulo, CM Webster, F Mou, ...
Cell 167 (7), 1705-1718. e13, 2016
2102016
Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2
M Yuan, E Pino, L Wu, M Kacergis, AA Soukas
Journal of Biological Chemistry 287 (35), 29579-29588, 2012
1832012
Metformin as anti-aging therapy: is it for everyone?
AA Soukas, H Hao, L Wu
Trends in Endocrinology & Metabolism 30 (10), 745-755, 2019
1822019
Mitochondrial permeability uncouples elevated autophagy and lifespan extension
B Zhou, J Kreuzer, C Kumsta, L Wu, KJ Kamer, L Cedillo, Y Zhang, S Li, ...
Cell 177 (2), 299-314. e16, 2019
1482019
Granzyme M directly cleaves inhibitor of caspase-activated DNase (CAD) to unleash CAD leading to DNA fragmentation
H Lu, Q Hou, T Zhao, H Zhang, Q Zhang, L Wu, Z Fan
The Journal of Immunology 177 (2), 1171-1178, 2006
952006
Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of …
D Hu, S Liu, L Shi, C Li, L Wu, Z Fan
Journal of biological chemistry 285 (24), 18326-18335, 2010
542010
Identification of SERPINB1 as a physiological inhibitor of human granzyme H
L Wang, Q Li, L Wu, S Liu, Y Zhang, X Yang, P Zhu, H Zhang, K Zhang, ...
The Journal of Immunology 190 (3), 1319-1330, 2013
492013
甲醛致人血淋巴细胞 DNA-蛋白质交联作用的定量研究
刘英帅, 鲁志松, 杨继文, 吴连锋, 杨旭
湖北预防医学杂志 15 (4), 4-7, 2004
392004
Metformin chlorination byproducts in drinking water exhibit marked toxicities of a potential health concern
R Zhang, Y He, L Yao, J Chen, S Zhu, X Rao, P Tang, J You, G Hua, ...
Environment International 146, 106244, 2021
372021
Genome-wide RNAi screen for fat regulatory genes in C. elegans identifies a proteostasis-AMPK axis critical for starvation survival
CM Webster, EC Pino, CE Carr, L Wu, B Zhou, L Cedillo, MC Kacergis, ...
Cell reports 20 (3), 627-640, 2017
352017
Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M
L Wu, L Wang, G Hua, K Liu, X Yang, Y Zhai, M Bartlam, F Sun, Z Fan
The Journal of Immunology 183 (1), 421-429, 2009
302009
Granzyme F induces a novel death pathway characterized by Bid-independent cytochrome c release without caspase activation
L Shi, L Wu, S Wang, Z Fan
Cell Death & Differentiation 16 (12), 1694-1706, 2009
282009
A non-canonical role for the C. elegans dosage compensation complex in growth and metabolic regulation downstream of TOR complex 2
CM Webster, L Wu, D Douglas, AA Soukas
Development 140 (17), 3601-3612, 2013
272013
Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
L Wang, K Zhang, L Wu, S Liu, H Zhang, Q Zhou, L Tong, F Sun, Z Fan
The Journal of Immunology 188 (2), 765-773, 2012
252012
Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
W Bian, M Tang, H Jiang, W Xu, W Hao, Y Sui, Y Hou, L Nie, H Zhang, ...
Developmental cell 56 (20), 2902-2919. e8, 2021
222021
Early-life vitamin B12 orchestrates lipid peroxidation to ensure reproductive success via SBP-1/SREBP1 in Caenorhabditis elegans
S Qin, Y Wang, L Li, J Liu, C Xiao, D Duan, W Hao, C Qin, J Chen, L Yao, ...
Cell Reports 40 (12), 2022
172022
Serum-and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase
B Zhou, Y Zhang, S Li, L Wu, G Fejes-Toth, A Naray-Fejes-Toth, ...
Cell reports 37 (1), 2021
132021
Quantitative assessment of near-infrared fluorescent proteins
H Zhang, S Papadaki, X Sun, X Wang, M Drobizhev, L Yao, M Rehbock, ...
Nature Methods 20 (10), 1605-1616, 2023
32023
The antidiabetic drug metformin aids bacteria in hijacking vitamin B12 from the environment through RcdA
L Yao, Y Wang, S Qin, S Zhu, L Wu
Communications Biology 6 (1), 96, 2023
32023
Cleavage of survivin by Granzyme M triggers degradation of the survivin-XIAP complex to free caspase activity leading to cytolysis of target tumor cells
D Hu, S Liu, L Shi, C Li, L Wu, Z Fan
J Biol Chem 285, 18326-18335, 2010
32010
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