| Distinct cellular mechanisms underlie anti-CTLA-4 and anti-PD-1 checkpoint blockade SC Wei, JH Levine, AP Cogdill, Y Zhao, NAAS Anang, MC Andrews, ... Cell 170 (6), 1120-1133. e17, 2017 | 1145 | 2017 |
| The chromatin accessibility landscape of primary human cancers MR Corces, JM Granja, S Shams, BH Louie, JA Seoane, W Zhou, ... Science 362 (6413), eaav1898, 2018 | 934 | 2018 |
| CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers S Vijayaraghavan, C Karakas, I Doostan, X Chen, T Bui, M Yi, ... Nature communications 8 (1), 15916, 2017 | 261 | 2017 |
| A genetic mouse model recapitulates immune checkpoint inhibitor–associated myocarditis and supports a mechanism-based therapeutic intervention SC Wei, WC Meijers, ML Axelrod, NAAS Anang, EM Screever, ... Cancer discovery 11 (3), 614-625, 2021 | 166 | 2021 |
| Sequential validation of blood-based protein biomarker candidates for early-stage pancreatic cancer M Capello, LE Bantis, G Scelo, Y Zhao, P Li, DS Dhillon, NJ Patel, ... JNCI: Journal of the National Cancer Institute 109 (4), djw266, 2017 | 132 | 2017 |
| Synthetic lethality of PARP inhibitors in combination with MYC blockade is independent of BRCA status in triple-negative breast cancer JPW Carey, C Karakas, T Bui, X Chen, S Vijayaraghavan, Y Zhao, J Wang, ... Cancer research 78 (3), 742-757, 2018 | 113 | 2018 |
| Diacetylspermine is a novel prediagnostic serum biomarker for non–small-cell lung cancer and has additive performance with pro-surfactant protein B WR Wikoff, S Hanash, B DeFelice, S Miyamoto, M Barnett, Y Zhao, ... Journal of clinical oncology 33 (33), 3880, 2015 | 106 | 2015 |
| Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models L Han, Q Zhang, M Dail, C Shi, A Cavazos, VR Ruvolo, Y Zhao, E Kim, ... Haematologica 105 (3), 697, 2020 | 94 | 2020 |
| c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun X Xie, TS Kaoud, R Edupuganti, T Zhang, T Kogawa, Y Zhao, ... Oncogene 36 (18), 2599-2608, 2017 | 86 | 2017 |
| Negative co-stimulation constrains T cell differentiation by imposing boundaries on possible cell states SC Wei, R Sharma, NAAS Anang, JH Levine, Y Zhao, JJ Mancuso, ... Immunity 50 (4), 1084-1098. e10, 2019 | 85 | 2019 |
| The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders CE Ang, Q Ma, OL Wapinski, SH Fan, RA Flynn, QY Lee, B Coe, ... Elife 8, e41770, 2019 | 70 | 2019 |
| Oral MEK 1/2 inhibitor trametinib in combination with AKT inhibitor GSK2141795 in patients with acute myeloid leukemia with RAS mutations: a phase II study BK Ragon, O Odenike, MR Baer, W Stock, G Borthakur, K Patel, L Han, ... Clinical Lymphoma Myeloma and Leukemia 19 (7), 431-440. e13, 2019 | 62 | 2019 |
| Structural modularity of the XIST ribonucleoprotein complex Z Lu, JK Guo, Y Wei, DR Dou, B Zarnegar, Q Ma, R Li, Y Zhao, F Liu, ... Nature Communications 11 (1), 6163, 2020 | 60 | 2020 |
| Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy YA Lyons, S Pradeep, SY Wu, M Haemmerle, JM Hansen, MJ Wagner, ... Oncotarget 8 (57), 96496, 2017 | 59 | 2017 |
| Elevation of TP53 autoantibody before CA125 in preclinical invasive epithelial ovarian cancer WL Yang, A Gentry-Maharaj, A Simmons, A Ryan, EO Fourkala, Z Lu, ... Clinical Cancer Research 23 (19), 5912-5922, 2017 | 59 | 2017 |
| An Unexpected FeCl3-Catalyzed Cascade Reaction of Indoles and o-Hydroxychalcones for the Assembly of Chromane-Bridged Polycyclic Indoles W Wang, X Bai, S Jin, J Guo, Y Zhao, H Miao, Y Zhu, Q Wang, Z Bu Organic letters 20 (12), 3451-3454, 2018 | 54 | 2018 |
| Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes T Zhou, S Li, B Huang, C Li, Y Zhao, J Chen, A Chen, Y Xiao, L Liu, ... Organic & Biomolecular Chemistry 15 (23), 4941-4945, 2017 | 52 | 2017 |
| Defining survivorship trajectories across patients with solid tumors: an evidence-based approach RL Dood, Y Zhao, SD Armbruster, RL Coleman, S Tworoger, AK Sood, ... JAMA oncology 4 (11), 1519-1526, 2018 | 50 | 2018 |
| Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome–like acute B-cell … Q Zhang, C Shi, L Han, N Jain, KG Roberts, H Ma, T Cai, A Cavazos, ... Oncotarget 9 (8), 8027, 2018 | 47 | 2018 |
| Dynamic chromatin regulatory landscape of human CAR T cell exhaustion DG Gennert, RC Lynn, JM Granja, EW Weber, MR Mumbach, Y Zhao, ... Proceedings of the National Academy of Sciences 118 (30), e2104758118, 2021 | 42 | 2021 |
