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Manway Liu
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-307, 2012
67632012
Next-generation characterization of the cancer cell line encyclopedia
M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ...
Nature 569 (7757), 503-508, 2019
16472019
Variable generalization performance of a deep learning model to detect pneumonia in chest radiographs: a cross-sectional study
JR Zech, MA Badgeley, M Liu, AB Costa, JJ Titano, EK Oermann
PLoS medicine 15 (11), e1002683, 2018
8562018
Characterization of the Novel and Specific PI3Kα Inhibitor NVP-BYL719 and Development of the Patient Stratification Strategy for Clinical TrialsNVP-BYL719 PI3Kα Inhibitor and …
C Fritsch, A Huang, C Chatenay-Rivauday, C Schnell, A Reddy, M Liu, ...
Molecular cancer therapeutics 13 (5), 1117-1129, 2014
4072014
CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors
SR Vora, D Juric, N Kim, M Mino-Kenudson, T Huynh, C Costa, ...
Cancer cell 26 (1), 136-149, 2014
4032014
AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas
M Elkabets, E Pazarentzos, D Juric, Q Sheng, RA Pelossof, S Brook, ...
Cancer cell 27 (4), 533-546, 2015
2812015
mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer
M Elkabets, S Vora, D Juric, N Morse, M Mino-Kenudson, T Muranen, ...
Science translational medicine 5 (196), 196ra99-196ra99, 2013
2772013
Network-based analysis of affected biological processes in type 2 diabetes models
M Liu, A Liberzon, SW Kong, WR Lai, PJ Park, IS Kohane, S Kasif
PLoS genetics 3 (6), e96, 2007
2252007
Deep learning predicts hip fracture using confounding patient and healthcare variables
MA Badgeley, JR Zech, L Oakden-Rayner, BS Glicksberg, M Liu, W Gale, ...
NPJ digital medicine 2 (1), 31, 2019
1592019
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism
C Lerin, AB Goldfine, T Boes, M Liu, S Kasif, JM Dreyfuss, ...
Molecular metabolism 5 (10), 926-936, 2016
1202016
Loss of Tuberous Sclerosis Complex 2 (TSC2) Is Frequent in Hepatocellular Carcinoma and Predicts Response to mTORC1 Inhibitor EverolimusFrequent TSC2 Loss in HCC and Everolimus …
H Huynh, HX Hao, SL Chan, D Chen, R Ong, KC Soo, P Pochanard, ...
Molecular cancer therapeutics 14 (5), 1224-1235, 2015
1112015
mTOR Inhibitors Synergize on Regression, Reversal of Gene Expression, and Autophagy in Hepatocellular Carcinoma
HE Thomas, CA Mercer, LS Carnevalli, J Park, JB Andersen, EA Conner, ...
Science Translational Medicine 4 (139), 139ra84-139ra84, 2012
992012
Accelerated postnatal growth increases lipogenic gene expression and adipocyte size in low–birth weight mice
E Isganaitis, J Jimenez-Chillaron, M Woo, A Chow, J DeCoste, M Vokes, ...
Diabetes 58 (5), 1192-1200, 2009
962009
The HSP90 Inhibitor NVP-AUY922 Potently Inhibits Non–Small Cell Lung Cancer GrowthHSP90 Inhibition in NSCLC
EB Garon, RS Finn, H Hamidi, J Dering, S Pitts, N Kamranpour, AJ Desai, ...
Molecular cancer therapeutics 12 (6), 890-900, 2013
782013
Confounding variables can degrade generalization performance of radiological deep learning models
JR Zech, MA Badgeley, M Liu, AB Costa, JJ Titano, EK Oermann
arXiv preprint arXiv:1807.00431, 2018
762018
A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease
MA Mori, M Liu, O Bezy, K Almind, H Shapiro, S Kasif, CR Kahn
Diabetes 59 (11), 2960-2971, 2010
722010
Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid
H Rĉder, FE McAllister, E Tjora, S Bhatt, I Haldorsen, J Hu, SM Willems, ...
Diabetes 63 (1), 259-269, 2014
522014
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 565 (7738), E5-E6, 2019
502019
Single agent activity of PIK3CA inhibitor BYL719 in a broad cancer cell line panel
A Huang, C Fritsch, C Wilson, A Reddy, M Liu, J Lehar, C Quadt, ...
Cancer research 72 (8_Supplement), 3749-3749, 2012
332012
CANDI: an R package and Shiny app for annotating radiographs and evaluating computer-aided diagnosis
MA Badgeley, M Liu, BS Glicksberg, M Shervey, J Zech, K Shameer, ...
Bioinformatics 35 (9), 1610-1612, 2019
72019
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