| Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ... Nature medicine 18 (4), 605-611, 2012 | 701 | 2012 |
| Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging DS Leeman, K Hebestreit, T Ruetz, AE Webb, A McKay, EA Pollina, ... Science 359 (6381), 1277-1283, 2018 | 403 | 2018 |
| Single-cell analysis reveals T cell infiltration in old neurogenic niches BW Dulken, MT Buckley, P Navarro Negredo, N Saligrama, R Cayrol, ... Nature 571 (7764), 205-210, 2019 | 393 | 2019 |
| Single-cell transcriptomic analysis defines heterogeneity and transcriptional dynamics in the adult neural stem cell lineage BW Dulken, DS Leeman, SC Boutet, K Hebestreit, A Brunet Cell reports 18 (3), 777-790, 2017 | 307 | 2017 |
| Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan S Han, EA Schroeder, CG Silva-García, K Hebestreit, WB Mair, A Brunet Nature 544 (7649), 185-190, 2017 | 284 | 2017 |
| Detection of significantly differentially methylated regions in targeted bisulfite sequencing data K Hebestreit, M Dugas, HU Klein Bioinformatics 29 (13), 1647-1653, 2013 | 251 | 2013 |
| Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, ... Nature 574 (7779), 553-558, 2019 | 223 | 2019 |
| The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium … A Kohlmann, HU Klein, S Weissmann, S Bresolin, T Chaplin, H Cuppens, ... Leukemia 25 (12), 1840-1848, 2011 | 138 | 2011 |
| DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding T Schoofs, C Rohde, K Hebestreit, HU Klein, S Göllner, I Schulze, ... Blood, The Journal of the American Society of Hematology 121 (1), 178-187, 2013 | 81 | 2013 |
| Leukemia gene atlas–a public platform for integrative exploration of genome-wide molecular data K Hebestreit, S Gröttrup, D Emden, J Veerkamp, C Ruckert, HU Klein, ... PloS one 7 (6), e39148, 2012 | 55 | 2012 |
| DNA methyltransferase inhibition reverses epigenetically embedded phenotypes in lung cancer preferentially affecting polycomb target genes A Hascher, AK Haase, K Hebestreit, C Rohde, HU Klein, M Rius, ... Clinical Cancer Research 20 (4), 814-826, 2014 | 48 | 2014 |
| An evaluation of methods to test predefined genomic regions for differential methylation in bisulfite sequencing data HU Klein, K Hebestreit Briefings in bioinformatics 17 (5), 796-807, 2016 | 46 | 2016 |
| Increased DNA methylation of Dnmt3b targets impairs leukemogenesis I Schulze, C Rohde, M Scheller-Wendorff, N Bäumer, A Krause, F Herbst, ... Blood, The Journal of the American Society of Hematology 127 (12), 1575-1586, 2016 | 42 | 2016 |
| Identification of the adapter molecule MTSS1 as a potential oncogene-specific tumor suppressor in acute myeloid leukemia M Schemionek, B Kharabi Masouleh, Y Klaile, U Krug, K Hebestreit, ... PloS one 10 (5), e0125783, 2015 | 28 | 2015 |
| MYST2 acetyltransferase expression and Histone H4 Lysine acetylation are suppressed in AML T Sauer, MF Arteaga, F Isken, C Rohde, K Hebestreit, JH Mikesch, ... Experimental hematology 43 (9), 794-802. e4, 2015 | 24 | 2015 |
| Identification of protein aggregates in the aging vertebrate brain with prion-like and phase separation properties I Harel, YR Chen, I Ziv, PP Singh, PN Negredo, U Goshtchevsky, W Wang, ... Biorxiv, 2022.02. 26.482115, 2022 | 18 | 2022 |
| Males induce premature demise of the opposite sex by multifaceted strategies LN Booth, C Shi, C Tantilert, RW Yeo, JW Miklas, K Hebestreit, ... Nature Aging 2 (9), 809-823, 2022 | 7 | 2022 |
| Biseq: A package for analyzing targeted bisulfite sequencing data K Hebestreit, HU Klein | 4 | 2015 |
| Males deploy multifaceted strategies and hijack longevity pathways to induce premature demise of the opposite sex LN Booth, C Shi, C Tantilert, RW Yeo, K Hebestreit, CN Hollenhorst, ... bioRxiv, 2020.06. 30.181008, 2020 | 3 | 2020 |
| Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution A Martirosyan, R Ansari, F Pestana, K Hebestreit, H Gasparyan, ... Molecular Neurodegeneration 19 (1), 7, 2024 | 2 | 2024 |
Kevin PetrieSenior Lecturer in Cell Biology, University of SunderlandVerified email at sunderland.ac.uk
