Asymmetric catalysis mediated by synthetic peptides EAC Davie, SM Mennen, Y Xu, SJ Miller Chemical reviews 107 (12), 5759-5812, 2007 | 703 | 2007 |
The evolution of high-throughput experimentation in pharmaceutical development and perspectives on the future SM Mennen, C Alhambra, CL Allen, M Barberis, S Berritt, TA Brandt, ... Organic Process Research & Development 23 (6), 1213-1242, 2019 | 333 | 2019 |
Thiazolylalanine-Derived Catalysts for Enantioselective Intermolecular Aldehyde− Imine Cross-Couplings SM Mennen, JD Gipson, YR Kim, SJ Miller Journal of the American Chemical Society 127 (6), 1654-1655, 2005 | 219 | 2005 |
Enantioselective total synthesis of (+)-gliocladine C: convergent construction of cyclotryptamine-fused polyoxopiperazines and a general approach for preparing … JE DeLorbe, SY Jabri, SM Mennen, LE Overman, FL Zhang Journal of the American Chemical Society 133 (17), 6549-6552, 2011 | 180 | 2011 |
General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)-and (−)-gliocladine C,(+)-leptosin D,(+ … JE DeLorbe, D Horne, R Jove, SM Mennen, S Nam, FL Zhang, ... Journal of the American Chemical Society 135 (10), 4117-4128, 2013 | 96 | 2013 |
A peptide-catalyzed asymmetric Stetter reaction SM Mennen, JT Blank, MB Tran-Dubé, JE Imbriglio, SJ Miller Chemical communications, 195-197, 2005 | 96 | 2005 |
Molecular complexity as a driver for chemical process innovation in the pharmaceutical industry S Caille, S Cui, MM Faul, SM Mennen, JS Tedrow, SD Walker The Journal of Organic Chemistry 84 (8), 4583-4603, 2019 | 65 | 2019 |
Development of a Bio-Inspired Acyl-Anion Equivalent Macrocyclization and Synthesis of a trans-Resorcylide Precursor SM Mennen, SJ Miller The Journal of Organic Chemistry 72 (14), 5260-5269, 2007 | 54 | 2007 |
Synthesis of aziridinomitosenes through base-catalyzed conjugate addition K Tsuboike, DJ Guerin, SM Mennen, SJ Miller Tetrahedron 60 (34), 7367-7374, 2004 | 27 | 2004 |
An improved synthesis of canthin-6-one KM Czerwinski, CA Zificsak, J Stevens, M Oberbeck, C Randlett, M King, ... Synthetic communications 33 (7), 1225-1231, 2003 | 17 | 2003 |
Synthesis of 4-Substituted Phthalazin-1(2H)-ones from 2-Acylbenzoic Acids: Controlling Hydrazine in a Pharmaceutical Intermediate through PAT-Guided Process … SM Mennen, ML Mak-Jurkauskas, MM Bio, LS Hollis, KA Nadeau, ... Organic Process Research & Development 19 (7), 884-891, 2015 | 16 | 2015 |
Xantphos as a Branch-Selective Ligand for the Acyclic sec-Alkyl Negishi Cross-Coupling of Heteroaryl Halides AH Cherney, SJ Hedley, SM Mennen, JS Tedrow Organometallics 38 (1), 97-102, 2018 | 15 | 2018 |
Effect of γ-substituted proline derivatives on the performance of the peptidic catalyst H-dPro-pro-Glu-NH2 T Schnitzer, H Wennemers Synthesis 50 (22), 4377-4382, 2018 | 15 | 2018 |
Synthesis of dipeptides by boronic acid catalysis H Tsuji, H Yamamoto Synlett 29 (03), 318-321, 2018 | 14 | 2018 |
Rapid Assembly of Molecular Complexity from Simple Enamides P Kramer, G Manolikakes Synlett 31 (11), 1027-1032, 2020 | 13 | 2020 |
Process development and protein engineering enhanced nitroreductase-catalyzed reduction of 2-methyl-5-nitro-pyridine A Bornadel, S Bisagni, A Pushpanath, I Slabu, J LePaih, AH Cherney, ... Organic Process Research & Development 25 (3), 648-653, 2020 | 11 | 2020 |
Development of a factory process for omecamtiv mecarbil, a novel cardiac myosin activator S Caille, AM Allgeier, C Bernard, TL Correll, A Cosbie, RD Crockett, S Cui, ... Organic Process Research & Development 23 (8), 1558-1567, 2019 | 11 | 2019 |
Salt of omecamtiv mecarbil and process for preparing salt S Cui, H Morrison, K Nagapudi, S Walker, C Bernard, KB Hansen, ... US Patent 9,988,354, 2018 | 11 | 2018 |
Synthesis of the Hydrazinyl Pyridine Intermediate: Phase-Appropriate Delivery A Wilsily, SM Mennen, A Cosbie, JE Milne Organic Process Research & Development 21 (9), 1286-1293, 2017 | 11 | 2017 |
Salt of omecamtiv mecarbil and process for preparing salt S Cui, H Morrison, K Nagapudi, S Walker, C Bernard, KB Hansen, ... US Patent App. 16/920,155, 2020 | 10 | 2020 |