| Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells E Habibi, AB Brinkman, J Arand, LI Kroeze, HHD Kerstens, F Matarese, ... Cell stem cell 13 (3), 360-369, 2013 | 494 | 2013 |
| Trials with ‘epigenetic’drugs: an update A Nebbioso, V Carafa, R Benedetti, L Altucci Molecular oncology 6 (6), 657-682, 2012 | 280 | 2012 |
| Targeting histone deacetylases in diseases: where are we? R Benedetti, M Conte, L Altucci Antioxidants & redox signaling 23 (1), 99-126, 2015 | 183 | 2015 |
| Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ... Journal of medicinal chemistry 57 (1), 42-55, 2014 | 133 | 2014 |
| c-Myc modulation and acetylation is a key HDAC inhibitor target in cancer A Nebbioso, V Carafa, M Conte, FP Tambaro, C Abbondanza, J Martens, ... Clinical Cancer Research 23 (10), 2542-2555, 2017 | 126 | 2017 |
| Psidium guajava L. anti‐neoplastic effects: induction of apoptosis and cell differentiation P Bontempo, A Doto, M Miceli, L Mita, R Benedetti, A Nebbioso, ... Cell proliferation 45 (1), 22-31, 2012 | 98 | 2012 |
| Biological interactions of biocompatible and water-dispersed MoS2 nanosheets with bacteria and human cells J Kaur, M Singh, C Dell ‘Aversana, R Benedetti, P Giardina, M Rossi, ... Scientific reports 8 (1), 16386, 2018 | 82 | 2018 |
| Indole-derived psammaplin A analogues as epigenetic modulators with multiple inhibitory activities R Pereira, R Benedetti, S Perez-Rodriguez, A Nebbioso, ... Journal of Medicinal Chemistry 55 (22), 9467-9491, 2012 | 55 | 2012 |
| Epigenetic profiling of the antitumor natural product psammaplin A and its analogues J García, G Franci, R Pereira, R Benedetti, A Nebbioso, ... Bioorganic & medicinal chemistry 19 (12), 3637-3649, 2011 | 55 | 2011 |
| The innovative potential of selenium-containing agents for fighting cancer and viral infections W Ali, R Benedetti, J Handzlik, C Zwergel, C Battistelli Drug Discovery Today 26 (1), 256-263, 2021 | 50 | 2021 |
| Breast cancer vaccines: new insights R Benedetti, C Dell’Aversana, C Giorgio, R Astorri, L Altucci Frontiers in endocrinology 8, 297422, 2017 | 48 | 2017 |
| Epigenetic-based therapy: From single-to multi-target approaches R Benedetti, M Conte, C Iside, L Altucci The international journal of biochemistry & cell biology 69, 121-131, 2015 | 48 | 2015 |
| Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs) C Milite, S Castellano, R Benedetti, A Tosco, C Ciliberti, C Vicidomini, ... Bioorganic & medicinal chemistry 19 (12), 3690-3701, 2011 | 48 | 2011 |
| Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer R Benedetti, C Dell’Aversana, T De Marchi, D Rotili, NQ Liu, B Novakovic, ... Cancers 11 (12), 2027, 2019 | 43 | 2019 |
| Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells P Bontempo, L Mita, A Doto, M Miceli, A Nebbioso, I Lepore, GL Franci, ... Journal of translational medicine 7, 1-8, 2009 | 42 | 2009 |
| Quinoline‐based p300 histone acetyltransferase inhibitors with pro‐apoptotic activity in human leukemia U937 cells A Lenoci, S Tomassi, M Conte, R Benedetti, V Rodriguez, S Carradori, ... ChemMedChem 9 (3), 542-548, 2014 | 32 | 2014 |
| HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape M Conte, C Dell'Aversana, R Benedetti, F Petraglia, A Carissimo, ... Oncotarget 6 (2), 886, 2015 | 31 | 2015 |
| Nonlinear protein–nucleic acid crosslinking induced by femtosecond UV laser pulses in living cells C Altucci, A Nebbioso, R Benedetti, R Esposito, V Carafa, M Conte, ... Laser Physics Letters 9 (3), 234, 2012 | 31 | 2012 |
| Harnessing the role of HDAC6 in idiopathic pulmonary fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors G Campiani, C Cavella, JD Osko, M Brindisi, N Relitti, S Brogi, ... Journal of medicinal chemistry 64 (14), 9960-9988, 2021 | 30 | 2021 |
| Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 L Pinzi, R Benedetti, L Altucci, G Rastelli ACS omega 5 (20), 11473-11480, 2020 | 29 | 2020 |
