| Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis K Brunner, S Maric, RS Reshma, H Almqvist, B Seashore-Ludlow, ... Journal of Medicinal Chemistry 59 (14), 6848-6859, 2016 | 56 | 2016 |
| Engineering of ancestors as a tool to elucidate structure, mechanism, and specificity of extant terpene cyclase K Schriever, P Saenz-Mendez, RS Rudraraju, NM Hendrikse, EP Hudson, ... Journal of the American Chemical Society 143 (10), 3794-3807, 2021 | 36 | 2021 |
| Mycobacterium tuberculosis lysine-ɛ-aminotransferase a potential target in dormancy: Benzothiazole based inhibitors RS Reshma, VU Jeankumar, N Kapoor, S Saxena, KA Bobesh, ... Bioorganic & Medicinal Chemistry 25 (10), 2761-2771, 2017 | 36 | 2017 |
| A robust synthesis of functionalized 2H-indazoles via solid state melt reaction (SSMR) and their anti-tubercular activity S Vidyacharan, C Adhikari, VS Krishna, RS Reshma, D Sriram, ... Bioorganic & medicinal chemistry letters 27 (7), 1593-1597, 2017 | 34 | 2017 |
| Engineering another class of anti-tubercular lead: Hit to lead optimization of an intriguing class of gyrase ATPase inhibitors VU Jeankumar, RS Reshma, R Vats, R Janupally, S Saxena, ... European Journal of Medicinal Chemistry 122, 216-231, 2016 | 33 | 2016 |
| Identification and development of benzoxazole derivatives as novel bacterial glutamate racemase inhibitors P Malapati, VS Krishna, R Nallangi, RR Srilakshmi, D Sriram European Journal of Medicinal Chemistry 145, 23-34, 2018 | 32 | 2018 |
| Enabling the (3+ 2) cycloaddition reaction in assembling newer anti-tubercular lead acting through the inhibition of the gyrase ATPase domain: lead optimization and structure … VU Jeankumar, RS Reshma, R Janupally, S Saxena, JP Sridevi, ... Organic & Biomolecular Chemistry 13 (8), 2423-2431, 2015 | 25 | 2015 |
| A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens P Vella, RS Rudraraju, T Lundbäck, H Axelsson, H Almqvist, M Vallin, ... Bioorganic & Medicinal Chemistry 30, 115898, 2021 | 17 | 2021 |
| Synthesis, in vitro, and in vivo (Zebra fish) antitubercular activity of 7, 8-dihydroquinolin-5 (6H)-ylidenehydrazinecarbothioamides S kumar Marvadi, VS Krishna, G Surineni, RS Reshma, B Sridhar, ... Bioorganic Chemistry 96, 103626, 2020 | 15 | 2020 |
| Profiling of in vitro activities of urea-based inhibitors against cysteine synthases from Mycobacterium tuberculosis K Brunner, EM Steiner, RS Reshma, D Sriram, R Schnell, G Schneider Bioorganic & Medicinal Chemistry Letters 27 (19), 4582-4587, 2017 | 15 | 2017 |
| Synthesis and anti-mycobacterial activity of 4-(4-phenyl-1H-1,2,3-triazol-1-yl)salicylhydrazones: revitalizing an old drug HHM Abdu-Allah, BGM Youssif, MH Abdelrahman, MK Abdel-Hamid, ... Archives of pharmacal research 40, 168-179, 2017 | 15 | 2017 |
| Design and development of new class of Mycobacterium tuberculosis L-alanine dehydrogenase inhibitors RS Reshma, S Saxena, KA Bobesh, VU Jeankumar, S Gunda, ... Bioorganic & Medicinal Chemistry 24 (18), 4499-4508, 2016 | 15 | 2016 |
| Synthesis and evaluation of 4′, 5′-dihydrospiro [piperidine-4, 7′-thieno [2, 3-c] pyran] analogues against both active and dormant Mycobacterium tuberculosis KK Alluri, RS Reshma, R Suraparaju, S Gottapu, D Sriram Bioorganic & Medicinal Chemistry 26 (8), 1462-1469, 2018 | 14 | 2018 |
| Lead identification and optimization of bacterial glutamate racemase inhibitors P Malapati, VS Krishna, R Nallangi, N Meda, RR Srilakshmi, D Sriram Bioorganic & Medicinal Chemistry 26 (1), 177-190, 2018 | 14 | 2018 |
| Structure‐Guided Discovery of Antitubercular Agents That Target the Gyrase ATPase Domain VU Jeankumar, S Saxena, R Vats, RS Reshma, R Janupally, P Kulkarni, ... ChemMedChem 11 (5), 539-548, 2016 | 14 | 2016 |
| Design and Development of Mycobacterium tuberculosis Lysine ɛ‐Aminotransferase Inhibitors for Latent Tuberculosis Infection BD Parthiban, S Saxena, M Chandran, PS Jonnalagadda, R Yadav, ... Chemical biology & drug design 87 (2), 265-274, 2016 | 9 | 2016 |
| Mycobacterium tuberculosis KasA as a drug target: Structure-based inhibitor design MBN Freundlich, Joel, Reshma S. Rudraraju, Samer Daher, Ricardo Gallardo ... Frontiers in Cellular and Infection Microbiology, 2022 | 8* | 2022 |
| Replacement of cardiotoxic aminopiperidine linker with piperazine moiety reduces cardiotoxicity? Mycobacterium tuberculosis novel bacterial topoisomerase inhibitors KA Bobesh, J Renuka, RR Srilakshmi, S Yellanki, P Kulkarni, ... Bioorganic & Medicinal Chemistry 24 (1), 42-52, 2016 | 8 | 2016 |
| Lead derivatization of ethyl 6-bromo-2-((dimethylamino) methyl)-5-hydroxy-1-phenyl-1H-indole-3-carboxylate and 5-bromo-2-(thiophene-2-carboxamido) benzoic acid as FabG … SD Varakala, RS Reshma, R Schnell, S Dharmarajan European Journal of Medicinal Chemistry 228, 113976, 2022 | 2 | 2022 |
| Design and development of novel inhibitors for the treatment of latent tuberculosis RS Reshma, P Yogeeswari, D Sriram The International Journal of Mycobacteriology 5 (Suppl 1), S121-S122, 2016 | 2 | 2016 |
