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Jacob L Litke
Jacob L Litke
Weill Cornell Medicine
Verified email at med.cornell.edu
Title
Cited by
Cited by
Year
Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts
JL Litke, SR Jaffrey
Nature biotechnology 37 (6), 667-675, 2019
2642019
Imaging metabolite dynamics in living cells using a Spinach-based riboswitch
M You, JL Litke, SR Jaffrey
Proceedings of the National Academy of Sciences 112 (21), E2756-E2765, 2015
2172015
Fluorophore‐promoted RNA folding and photostability enables imaging of single broccoli‐tagged mRNAs in live mammalian cells
X Li, H Kim, JL Litke, J Wu, SR Jaffrey
Angewandte Chemie International Edition 59 (11), 4511-4518, 2020
882020
Imaging Intracellular S-Adenosyl Methionine Dynamics in Live Mammalian Cells with a Genetically Encoded Red Fluorescent RNA-Based Sensor
X Li, L Mo, JL Litke, SK Dey, SR Suter, SR Jaffrey
Journal of the American Chemical Society 142 (33), 14117-14124, 2020
602020
Detection of low-abundance metabolites in live cells using an RNA integrator
M You, JL Litke, R Wu, SR Jaffrey
Cell chemical biology 26 (4), 471-481. e3, 2019
412019
Developing fluorogenic riboswitches for imaging metabolite concentration dynamics in bacterial cells
JL Litke, M You, SR Jaffrey
Methods in enzymology 572, 315-333, 2016
282016
Naturally occurring three-way junctions can be repurposed as genetically encoded RNA-based sensors
JD Moon, J Wu, SK Dey, JL Litke, X Li, H Kim, SR Jaffrey
Cell chemical biology 28 (11), 1569-1580. e4, 2021
172021
Probing the ion binding site in a DNA Holliday junction using Förster resonance energy transfer (FRET)
JL Litke, Y Li, LM Nocka, I Mukerji
International journal of molecular sciences 17 (3), 366, 2016
142016
Trans ligation of RNAs to generate hybrid circular RNAs using highly efficient autocatalytic transcripts
JL Litke, SR Jaffrey
Methods 196, 104-112, 2021
122021
Designing and expressing circular RNA aptamers to regulate mammalian cell biology
JL Litke, SR Jaffrey
Nucleic Acid Aptamers: Selection, Characterization, and Application, 223-234, 2022
22022
RNA molecules, methods of producing circular RNA, and treatment methods
SR Jaffrey, JL Litke
US Patent 11,756,183, 2023
12023
Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
T Hagen, JL Litke, N Nasir, Q Hou, SR Jaffrey
Cell Chemical Biology 31 (10), 1827-1838. e7, 2024
2024
Rna molecules, methods of producing circular rna, and treatment methods
SR Jaffrey, JL Litke
US Patent App. 18/355,546, 2024
2024
A Ribozyme-Mediated Mammalian Expression System and Its Utility for RNA-Based Devices and Aptamers in Live Cells
JL Litke
Weill Medical College of Cornell University, 2019
2019
Structure of DNA Four-Way Junctions: Effect of Ions and Proteins
I Mukerji, CI Vitoc, J Litke, E Wheatley, O Buzovetsky, Y Li, DL Beveridge
Biophysical Journal 102 (3), 75a, 2012
2012
Probing the Ion-Binding Site of the Holliday Junction
J Litke, I Mukerji
Biophysical Journal 100 (3), 322a, 2011
2011
Probing the Ion-Binding Site of the Holliday Junction: A Spectroscopic and Calorimetric Approach
JL Litke
2011
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