|PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation|
MZ Noman, G Desantis, B Janji, M Hasmim, S Karray, P Dessen, V Bronte, ...
Journal of Experimental Medicine 211 (5), 781-790, 2014
|Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell–mediated lysis|
I Akalay, B Janji, M Hasmim, MZ Noman, F André, P De Cremoux, ...
Cancer research 73 (8), 2418-2427, 2013
|Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression|
MZ Noman, B Janji, B Kaminska, K Van Moer, S Pierson, P Przanowski, ...
Cancer research 71 (18), 5976-5986, 2011
|The cooperative induction of hypoxia-inducible factor-1α and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis|
MZ Noman, S Buart, J Van Pelt, C Richon, M Hasmim, N Leleu, ...
The Journal of Immunology 182 (6), 3510-3521, 2009
|Hypoxia: a key player in antitumor immune response. A review in the theme: cellular responses to hypoxia|
MZ Noman, M Hasmim, Y Messai, S Terry, C Kieda, B Janji, S Chouaib
American Journal of Physiology-Cell Physiology 309 (9), C569-C579, 2015
|Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells|
MZ Noman, S Buart, P Romero, S Ketari, B Janji, B Mari, F Mami-Chouaib, ...
Cancer research 72 (18), 4629-4641, 2012
|Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia|
J Baginska, E Viry, G Berchem, A Poli, MZ Noman, K van Moer, S Medves, ...
Proceedings of the National Academy of Sciences 110 (43), 17450-17455, 2013
|Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer|
G Berchem, MZ Noman, M Bosseler, J Paggetti, S Baconnais, E Le Cam, ...
Oncoimmunology 5 (4), e1062968, 2016
|Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer|
S Chouaib, MZ Noman, K Kosmatopoulos, MA Curran
Oncogene 36 (4), 439-445, 2017
|Human mesenchymal stem cells derived from induced pluripotent stem cells down-regulate NK-cell cytolytic machinery|
M Giuliani, N Oudrhiri, ZM Noman, A Vernochet, S Chouaib, B Azzarone, ...
Blood, The Journal of the American Society of Hematology 118 (12), 3254-3262, 2011
|Hypoxia promotes tumor growth in linking angiogenesis to immune escape|
S Chouaib, Y Messai, S Couve, B Escudier, M Hasmim, MZ Noman
Frontiers in immunology 3, 21, 2012
|Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response|
MZ Noman, Y Messai, T Carre, I Akalay, M Meron, B Janji, M Hasmim, ...
Critical Reviews™ in Immunology 31 (5), 2011
|Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells|
S Chouaib, C Kieda, H Benlalam, MZ Noman, F Mami-Chouaib, C Ruegg
Critical Reviews™ in Immunology 30 (6), 2010
|ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy|
Y Messai, MZ Noman, M Hasmim, B Janji, A Tittarelli, M Boutet, V Baud, ...
Cancer research 74 (23), 6820-6832, 2014
|The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200|
MZ Noman, B Janji, A Abdou, M Hasmim, S Terry, TZ Tan, ...
Oncoimmunology 6 (1), e1263412, 2017
|Immune surveillance of human cancer: if the cytotoxic T‐lymphocytes play the music, does the tumoral system call the tune?|
A Hamai, H Benlalam, F Meslin, M Hasmim, T Carre, I Akalay, B Janji, ...
Tissue antigens 75 (1), 1-8, 2010
|Renal cell carcinoma programmed death-ligand 1, a new direct target of hypoxia-inducible factor-2 alpha, is regulated by von Hippel–Lindau gene mutation status|
Y Messai, S Gad, MZ Noman, G Le Teuff, S Couve, B Janji, SF Kammerer, ...
European urology 70 (4), 623-632, 2016
|Critical role of tumor microenvironment in shaping NK cell functions: implication of hypoxic stress|
M Hasmim, Y Messai, L Ziani, J Thiery, JH Bouhris, MZ Noman, ...
Frontiers in immunology 6, 482, 2015
|Cutting edge: hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1|
M Hasmim, MZ Noman, Y Messai, D Bordereaux, G Gros, V Baud, ...
The Journal of Immunology 191 (12), 5802-5806, 2013
|Tumor-promoting effects of myeloid-derived suppressor cells are potentiated by hypoxia-induced expression of miR-210|
MZ Noman, B Janji, S Hu, JC Wu, F Martelli, V Bronte, S Chouaib
Cancer research 75 (18), 3771-3787, 2015