David M. Margolis
David M. Margolis
Verified email at med.unc.edu - Homepage
Cited by
Cited by
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
NM Archin, AL Liberty, AD Kashuba, SK Choudhary, JD Kuruc, ...
Nature 487 (7408), 482-485, 2012
The challenge of finding a cure for HIV infection
DD Richman, DM Margolis, M Delaney, WC Greene, D Hazuda, ...
Science 323 (5919), 1304-1307, 2009
Depletion of latent HIV-1 infection in vivo: a proof-of-concept study
G Lehrman, IB Hogue, S Palmer, C Jennings, CA Spina, A Wiegand, ...
The Lancet 366 (9485), 549-555, 2005
Towards an HIV cure: a global scientific strategy
SG Deeks, B Autran, B Berkhout, M Benkirane, S Cairns, N Chomont, ...
Nature reviews Immunology 12 (8), 607, 2012
Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid
NM Archin, A Espeseth, D Parker, M Cheema, D Hazuda, DM Margolis
AIDS research and human retroviruses 25 (2), 207-212, 2009
The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1
JJ Coull, F Romerio, JM Sun, JL Volker, KM Galvin, JR Davie, Y Shi, ...
Journal of virology 74 (15), 6790-6799, 2000
Inhibition of HIV fusion with multivalent gold nanoparticles
MC Bowman, TE Ballard, CJ Ackerson, DL Feldheim, DM Margolis, ...
Journal of the American Chemical Society 130 (22), 6896-6897, 2008
An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients
CA Spina, J Anderson, NM Archin, A Bosque, J Chan, M Famiglietti, ...
PLoS Pathog 9 (12), e1003834, 2013
The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial
RT Gandhi, L Zheng, RJ Bosch, ES Chan, DM Margolis, S Read, ...
PLoS Med 7 (8), e1000321, 2010
Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression
L Ylisastigui, NM Archin, G Lehrman, RJ Bosch, DM Margolis
Aids 18 (8), 1101-1108, 2004
International AIDS Society global scientific strategy: towards an HIV cure 2016
SG Deeks, SR Lewin, AL Ross, J Ananworanich, M Benkirane, P Cannon, ...
Nature medicine 22 (8), 839, 2016
Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor …
G He, DM Margolis
Molecular and cellular biology 22 (9), 2965-2973, 2002
BET bromodomain inhibition as a novel strategy for reactivation of HIV‐1
C Banerjee, N Archin, D Michaels, AC Belkina, GV Denis, J Bradner, ...
Journal of leukocyte biology 92 (6), 1147-1154, 2012
Trimethoprim-sulfamethoxazole prophylaxis in the management of chronic granulomatous disease
DM Margolis, DA Melnick, DW Ailing, JI Gallin
Journal of Infectious Diseases 162 (3), 723-726, 1990
Eradicating HIV-1 infection: seeking to clear a persistent pathogen
NM Archin, JM Sung, C Garrido, N Soriano-Sarabia, DM Margolis
Nature Reviews Microbiology 12 (11), 750-764, 2014
c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter
G Jiang, A Espeseth, DJ Hazuda, DM Margolis
Journal of virology 81 (20), 10914-10923, 2007
Precise quantitation of the latent HIV-1 reservoir: implications for eradication strategies
AM Crooks, R Bateson, AB Cope, NP Dahl, MK Griggs, JAD Kuruc, ...
The Journal of infectious diseases 212 (9), 1361-1365, 2015
Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2
J Friedman, WK Cho, CK Chu, KS Keedy, NM Archin, DM Margolis, J Karn
Journal of virology 85 (17), 9078-9089, 2011
HIV-1 Expression Within Resting CD4+ T Cells After Multiple Doses of Vorinostat
NM Archin, R Bateson, MK Tripathy, AM Crooks, KH Yang, NP Dahl, ...
The Journal of infectious diseases 210 (5), 728-735, 2014
Neurocognitive effects of treatment interruption in stable HIV-positive patients in an observational cohort
KR Robertson, Z Su, DM Margolis, A Krambrink, DV Havlir, S Evans, ...
Neurology 74 (16), 1260-1266, 2010
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