|IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a|
MCT Hu, DF Lee, W Xia, LS Golfman, F Ou-Yang, JY Yang, Y Zou, S Bao, ...
Cell 117 (2), 225-237, 2004
|Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome|
X Carvajal-Vergara, A Sevilla, SL D’Souza, YS Ang, C Schaniel, DF Lee, ...
Nature 465 (7299), 808-812, 2010
|IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway|
DF Lee, HP Kuo, CT Chen, JM Hsu, CK Chou, Y Wei, HL Sun, LY Li, ...
Cell 130 (3), 440-455, 2007
|ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation|
JY Yang, CS Zong, W Xia, H Yamaguchi, Q Ding, X Xie, JY Lang, CC Lai, ...
Nature cell biology 10 (2), 138-148, 2008
|Erk associates with and primes GSK-3β for its inactivation resulting in upregulation of β-catenin|
Q Ding, W Xia, JC Liu, JY Yang, DF Lee, J Xia, G Bartholomeusz, Y Li, ...
Molecular cell 19 (2), 159-170, 2005
|Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network|
YS Ang, SY Tsai, DF Lee, J Monk, J Su, K Ratnakumar, J Ding, Y Ge, ...
Cell 145 (2), 183-197, 2011
|KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma|
J Ling, Y Kang, R Zhao, Q Xia, DF Lee, Z Chang, J Li, B Peng, JB Fleming, ...
Cancer cell 21 (1), 105-120, 2012
|Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization|
Q Ding, X He, JM Hsu, W Xia, CT Chen, LY Li, DF Lee, JC Liu, Q Zhong, ...
Molecular and cellular biology 27 (11), 4006-4017, 2007
|Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2|
SC Wang, HC Lien, W Xia, IF Chen, HW Lo, Z Wang, M Ali-Seyed, DF Lee, ...
Cancer cell 6 (3), 251-261, 2004
|KEAP1 E3 ligase-mediated downregulation of NF-κB signaling by targeting IKKβ|
DF Lee, HP Kuo, M Liu, CK Chou, W Xia, Y Du, J Shen, CT Chen, L Huo, ...
Molecular cell 36 (1), 131-140, 2009
|The crosstalk of mTOR/S6K1 and Hedgehog pathways|
Y Wang, Q Ding, CJ Yen, W Xia, JG Izzo, JY Lang, CW Li, JL Hsu, ...
Cancer cell 21 (3), 374-387, 2012
|FOXO1 is an essential regulator of pluripotency in human embryonic stem cells|
X Zhang, S Yalcin, DF Lee, TYJ Yeh, SM Lee, J Su, SK Mungamuri, ...
Nature cell biology 13 (9), 1092-1099, 2011
|Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor|
DK Giri, M Ali-Seyed, LY Li, DF Lee, P Ling, G Bartholomeusz, SC Wang, ...
Molecular and cellular biology 25 (24), 11005-11018, 2005
|Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3β activity and associates with poor prognosis in human breast cancer|
Q Ding, X He, W Xia, JM Hsu, CT Chen, LY Li, DF Lee, JY Yang, X Xie, ...
Cancer research 67 (10), 4564-4571, 2007
|Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer|
Q Ding, L Huo, JY Yang, W Xia, Y Wei, Y Liao, CJ Chang, Y Yang, CC Lai, ...
Cancer research 68 (15), 6109-6117, 2008
|Coordination of m6A mRNA methylation and gene transcription by ZFP217 regulates pluripotency and reprogramming|
F Aguilo, F Zhang, A Sancho, M Fidalgo, S Di Cecilia, A Vashisht, DF Lee, ...
Cell stem cell 17 (6), 689-704, 2015
|Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast …|
W Xia, JS Chen, X Zhou, PR Sun, DF Lee, Y Liao, BP Zhou, MC Hung
Clinical Cancer Research 10 (11), 3815-3824, 2004
|Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells|
SY Tsai, C Clavel, S Kim, YS Ang, L Grisanti, DF Lee, K Kelley, M Rendl
Stem cells 28 (2), 221-228, 2010
|Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1|
C Li, J Ao, J Fu, DF Lee, J Xu, D Lonard, BW O'Malley
Oncogene 30 (42), 4350-4364, 2011
|Modeling familial cancer with induced pluripotent stem cells|
DF Lee, J Su, HS Kim, B Chang, D Papatsenko, R Zhao, Y Yuan, ...
Cell 161 (2), 240-254, 2015