Rolen Quadros
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Reprogramming human T cell function and specificity with non-viral genome targeting
TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ...
Nature 559 (7714), 405-409, 2018
Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins
RM Quadros, H Miura, DW Harms, H Akatsuka, T Sato, T Aida, R Redder, ...
Genome biology 18, 1-15, 2017
Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors
H Miura, RM Quadros, CB Gurumurthy, M Ohtsuka
Nature protocols 13 (1), 195-215, 2018
Mouse genome editing using the CRISPR/Cas system
DW Harms, RM Quadros, D Seruggia, M Ohtsuka, G Takahashi, ...
Current protocols in human genetics 83 (1), 15.7. 1-15.7. 27, 2014
Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes
AM Jacobi, GR Rettig, R Turk, MA Collingwood, SA Zeiner, RM Quadros, ...
Methods 121, 16-28, 2017
Cleavage by caspase 8 and mitochondrial membrane association activate the BH3-only protein Bid during TRAIL-induced apoptosis
K Huang, J Zhang, KL O’Neill, CB Gurumurthy, RM Quadros, Y Tu, X Luo
Journal of Biological Chemistry 291 (22), 11843-11851, 2016
Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I
N Gomez-Ospina, SG Scharenberg, N Mostrel, RO Bak, S Mantri, ...
Nature Communications, 2019
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation
CB Gurumurthy, AR O’brien, RM Quadros, J Adams, P Alcaide, S Ayabe, ...
Genome biology 20 (1), 1-14, 2019
CRISPR: a versatile tool for both forward and reverse genetics research
CB Gurumurthy, M Grati, M Ohtsuka, SLP Schilit, RM Quadros, XZ Liu
Human genetics 135, 971-976, 2016
Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice
H Wu, C Petitpré, P Fontanet, A Sharma, C Bellardita, RM Quadros, ...
Nature communications 12 (1), 1026, 2021
CD4+ effector T cells accelerate Alzheimer’s disease in mice
J Machhi, P Yeapuri, Y Lu, E Foster, R Chikhale, J Herskovitz, ...
Journal of Neuroinflammation 18 (1), 1-23, 2021
Genetically modified mouse models to help fight COVID-19
CB Gurumurthy, RM Quadros, GP Richardson, LY Poluektova, ...
Nature protocols 15 (12), 3777-3787, 2020
Insertion of sequences at the original provirus integration site of mouseROSA26 locus using the CRISPR/Cas9 system
RM Quadros, DW Harms, M Ohtsuka, CB Gurumurthy
FEBS open bio 5 (1), 191-197, 2015
Ca2+ sensor synaptotagmin-1 mediates exocytosis in mammalian photoreceptors
JJ Grassmeyer, AL Cahill, CL Hays, C Barta, RM Quadros, ...
Elife 8, e45946, 2019
Sedative effect of Clozapine is a function of 5-HT2A and environmental novelty
RS Joshi, R Quadros, M Drumm, R Ain, MM Panicker
European Neuropsychopharmacology 27 (1), 70-81, 2017
Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening
CB Gurumurthy, PS Joshi, SG Kurz, M Ohtsuka, RM Quadros, DW Harms, ...
International Journal of Genomics 2015, 2015
Pronuclear Injection‐Based Targeted Transgenesis
SLP Schilit, M Ohtsuka, RM Quadros, CB Gurumurthy
Current protocols in human genetics 91 (1), 15.10. 1-15.10. 28, 2016
Antiretroviral drug metabolism in humanized PXR-CAR-CYP3A-NOG mice
JEM McMillan, DA Cobb, Z Lin, MG Banoub, RS Dagur, AAB Woods, ...
Journal of Pharmacology and Experimental Therapeutics 365 (2), 272-280, 2018
CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies
CB Gurumurthy, RM Quadros, M Sato, T Mashimo, KCK Lloyd, M Ohtsuka
Genome editing, 65-77, 2016
Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model
S Tarang, SMSR Doi, CB Gurumurthy, D Harms, R Quadros, ...
Frontiers in cellular neuroscience 9, 52, 2015
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