| The growing applications of SuFEx click chemistry AS Barrow, CJ Smedley, Q Zheng, S Li, J Dong, JE Moses Chemical Society Reviews 48 (17), 4731-4758, 2019 | 337 | 2019 |
| SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase Q Zheng, JL Woehl, S Kitamura, D Santos-Martins, CJ Smedley, G Li, ... Proceedings of the National Academy of Sciences 116 (38), 18808-18814, 2019 | 143 | 2019 |
| Diversity oriented clicking (DOC): divergent synthesis of SuFExable pharmacophores from 2‐substituted‐alkynyl‐1‐sulfonyl fluoride (SASF) hubs CJ Smedley, G Li, AS Barrow, TL Gialelis, MC Giel, A Ottonello, Y Cheng, ... Angewandte Chemie 132 (30), 12560-12569, 2020 | 89 | 2020 |
| Metal‐free synthesis of functional 1‐substituted‐1, 2, 3‐triazoles from ethenesulfonyl fluoride and organic azides MC Giel, CJ Smedley, ERR Mackie, T Guo, J Dong, TP Soares da Costa, ... Angewandte Chemie 132 (3), 1197-1202, 2020 | 73 | 2020 |
| 1-Bromoethene-1-sulfonyl fluoride (BESF) is another good connective hub for SuFEx click chemistry CJ Smedley, MC Giel, A Molino, AS Barrow, DJD Wilson, JE Moses Chemical communications 54 (47), 6020-6023, 2018 | 72 | 2018 |
| Bifluoride ion mediated SuFEx trifluoromethylation of sulfonyl fluorides and iminosulfur oxydifluorides CJ Smedley, Q Zheng, B Gao, S Li, A Molino, HM Duivenvoorden, ... Angewandte Chemie International Edition 58 (14), 4552-4556, 2019 | 67 | 2019 |
| Accelerated SuFEx click chemistry for modular synthesis CJ Smedley, JA Homer, TL Gialelis, AS Barrow, RA Koelln, JE Moses Angewandte Chemie 134 (4), e202112375, 2022 | 63 | 2022 |
| Sulfur–Fluoride Exchange (SuFEx)‐Mediated Synthesis of Sterically Hindered and Electron‐Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates CJ Smedley, AS Barrow, C Spiteri, MC Giel, P Sharma, JE Moses Chemistry–A European Journal 23 (42), 9990-9995, 2017 | 40 | 2017 |
| Structure Activity Relationships of αv Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents J Adams, EC Anderson, EE Blackham, YWR Chiu, T Clarke, N Eccles, ... ACS Medicinal Chemistry Letters 5 (11), 1207-1212, 2014 | 31 | 2014 |
| Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors Y Cheng, G Li, CJ Smedley, MC Giel, S Kitamura, JL Woehl, G Bianco, ... Proceedings of the National Academy of Sciences 119 (37), e2208540119, 2022 | 13 | 2022 |
| Sustainable syntheses of (−)-jerantinines A & E and structural characterisation of the jerantinine-tubulin complex at the colchicine binding site CJ Smedley, PA Stanley, ME Qazzaz, AE Prota, N Olieric, H Collins, ... Scientific reports 8 (1), 10617, 2018 | 13 | 2018 |
| Phosphorus fluoride exchange: Multidimensional catalytic click chemistry from phosphorus connective hubs S Sun, JA Homer, CJ Smedley, QQ Cheng, KB Sharpless, JE Moses Chem 9 (8), 2128-2143, 2023 | 10 | 2023 |
| A diversity oriented clicking strategy: the stereoselective synthesis of highly-functionalised olefins from 2-substituted-alkynyl-1-sulfonyl fluorides CJ Smedley Chemical Communications 58 (80), 11316-11319, 2022 | 5 | 2022 |
| Aminium cation-radical catalysed selective hydration of (E)-aryl enynes MC Giel, AS Barrow, CJ Smedley, W Lewis, JE Moses Chemical Communications 57 (57), 6991-6994, 2021 | 4 | 2021 |
| Ethene‐1, 1‐disulfonyl Difluoride (EDSF) for SuFEx Click Chemistry: Synthesis of SuFExable 1, 1‐Bissulfonylfluoride Substituted Cyclobutene Hubs CJ Smedley, MC Giel, T Fallon, JE Moses Angewandte Chemie International Edition 62 (30), e202303916, 2023 | 3 | 2023 |
| Phosphorus (V) fluoride exchange (PFEx): multidimensional click chemistry from phosphorus (V) connective hubs S Sun, CJ Smedley, JA Homer, QQ Cheng, KB Sharpless, JE Moses | 2 | 2022 |
| Sulfur fluoride exchange (SuFEx) MC Giel, CJ Smedley, JE Moses | 2 | 2021 |
| “Sleeping beauty” phenomenon: SuFEx-enabled discovery of selective covalent inhibitors of human neutrophil elastase Q Zheng, JL Woehl, S Kitamura, D Santos-Martins, CJ Smedley, G Li, ... | 2 | 2019 |
| Inhibition of mitochondrial metabolism by (−)-jerantinine A: synthesis and biological studies in triple-negative breast cancer cells TL Gialelis, Z Wang, JA Homer, WH Yang, T Chung, Q Hu, CJ Smedley, ... RSC Medicinal Chemistry 14 (4), 710-714, 2023 | 1 | 2023 |
| Diversity Oriented Clicking: Synthesis of beta-Substituted Alkenyl Sulfonyl Fluorides as Covalent Human Neutrophil Elastase Inhibitors Y Cheng, G Li, CJ Smedley, MC Giel, S Kitamura, JL Woehl, G Bianco, ... | | 2022 |
John E. MosesProfessor of Click ChemistryVerified email at cshl.edu
