Michael Comb
Michael Comb
CEO cell Signaling technology
Verified email at cellsignal.com
TitleCited byYear
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
K Rikova, A Guo, Q Zeng, A Possemato, J Yu, H Haack, J Nardone, K Lee, ...
Cell 131 (6), 1190-1203, 2007
20792007
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
J Rush, A Moritz, KA Lee, A Guo, VL Goss, EJ Spek, H Zhang, XM Zha, ...
Nature biotechnology 23 (1), 94, 2005
11222005
Systematic and quantitative assessment of the ubiquitin-modified proteome
W Kim, EJ Bennett, EL Huttlin, A Guo, J Li, A Possemato, ME Sowa, ...
Molecular cell 44 (2), 325-340, 2011
11052011
A cyclic AMP-and phorbol ester-inducible DNA element
M Comb, NC Birnberg, A Seasholtz, E Herbert, HM Goodman
Nature 323 (6086), 353, 1986
7331986
FGF and stress regulate CREB and ATF‐1 via a pathway involving p38 MAP kinase and MAPKAP kinase‐2.
YI Tan, J Rouse, A Zhang, S Cariati, P Cohen, MJ Comb
The EMBO journal 15 (17), 4629-4642, 1996
7291996
Primary structure of the human Met-and Leu-enkephalin precursor and its mRNA
M Comb, PH Seeburg, J Adelman, L Eiden, E Herbert
Nature 295 (5851), 663, 1982
7281982
Signaling networks assembled by oncogenic EGFR and c-Met
A Guo, J VillÚn, J Kornhauser, KA Lee, MP Stokes, K Rikova, ...
Proceedings of the National Academy of Sciences 105 (2), 692-697, 2008
5132008
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2
M Comb, HM Goodman
Nucleic acids research 18 (13), 3975-3982, 1990
4591990
Regulation of the p70 S6 kinase by phosphorylation in vivo analysis using site-specific anti-phosphopeptide antibodies
QP Weng, M Kozlowski, C Belham, A Zhang, MJ Comb, J Avruch
Journal of Biological Chemistry 273 (26), 16621-16629, 1998
4101998
FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions
RT Peterson, PA Beal, MJ Comb, SL Schreiber
Journal of Biological Chemistry 275 (10), 7416-7423, 2000
3652000
Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.
M Comb, N Mermod, SE Hyman, J Pearlberg, ME Ross, HM Goodman
The EMBO journal 7 (12), 3793-3805, 1988
3381988
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
Y Tan, MR Demeter, H Ruan, MJ Comb
Journal of Biological Chemistry 275 (33), 25865-25869, 2000
3282000
Profiling of UV-induced ATM/ATR signaling pathways
MP Stokes, J Rush, J MacNeill, JM Ren, K Sprott, J Nardone, V Yang, ...
Proceedings of the National Academy of Sciences 104 (50), 19855-19860, 2007
2902007
Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs
H Zhang, X Zha, Y Tan, PV Hornbeck, AJ Mastrangelo, DR Alessi, ...
Journal of Biological Chemistry 277 (42), 39379-39387, 2002
2852002
Survival-and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome c, and activation of caspase-like proteases
YB Ouyang, Y Tan, M Comb, CL Liu, ME Martone, BK Siesj÷, BR Hu
Journal of Cerebral Blood Flow & Metabolism 19 (10), 1126-1135, 1999
2801999
Immunoaffinity enrichment and mass spectrometry analysis of protein methylation
A Guo, H Gu, J Zhou, D Mulhern, Y Wang, KA Lee, V Yang, M Aguiar, ...
Molecular & Cellular Proteomics 13 (1), 372-387, 2014
2792014
p90RSK blocks Bad-mediated cell death via a protein kinase C-dependent pathway
Y Tan, H Ruan, MR Demeter, MJ Comb
Journal of Biological Chemistry 274 (49), 34859-34867, 1999
2751999
Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma
TL Gu, X Deng, F Huang, M Tucker, K Crosby, V Rimkunas, Y Wang, ...
PloS one 6 (1), e15640, 2011
2692011
Mutation-specific antibodies for the detection of EGFR mutations in non–small-cell lung cancer
J Yu, S Kane, J Wu, E Benedettini, D Li, C Reeves, G Innocenti, R Wetzel, ...
Clinical Cancer Research 15 (9), 3023-3028, 2009
2692009
Akt–RSK–S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases
A Moritz, Y Li, A Guo, J VillÚn, Y Wang, J MacNeill, J Kornhauser, K Sprott, ...
Sci. Signal. 3 (136), ra64-ra64, 2010
2532010
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