| Metazoan Hsp70 machines use Hsp110 to power protein disaggregation H Rampelt, J Kirstein‐Miles, NB Nillegoda, K Chi, SR Scholz, RI Morimoto, ... The EMBO journal 31 (21), 4221-4235, 2012 | 248 | 2012 |
| Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases J Kirstein, N Molière, DA Dougan, K Turgay Nature Reviews Microbiology 7 (8), 589-599, 2009 | 213 | 2009 |
| Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation NB Nillegoda, J Kirstein, A Szlachcic, M Berynskyy, A Stank, F Stengel, ... Nature 524 (7564), 247-251, 2015 | 202 | 2015 |
| The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease J Kirstein, A Hoffmann, H Lilie, R Schmidt, H Rübsamen‐Waigmann, ... EMBO molecular medicine 1 (1), 37-49, 2009 | 177 | 2009 |
| Adaptor protein controlled oligomerization activates the AAA+ protein ClpC J Kirstein, T Schlothauer, DA Dougan, H Lilie, G Tischendorf, A Mogk, ... The EMBO journal 25 (7), 1481-1491, 2006 | 146 | 2006 |
| Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments T Haslberger, A Zdanowicz, I Brand, J Kirstein, K Turgay, A Mogk, ... Nature structural & molecular biology 15 (6), 641, 2008 | 140 | 2008 |
| The nascent polypeptide‐associated complex is a key regulator of proteostasis J Kirstein‐Miles, A Scior, E Deuerling, RI Morimoto The EMBO journal 32 (10), 1451-1468, 2013 | 130 | 2013 |
| A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis J Kirstein, D Zühlke, U Gerth, K Turgay, M Hecker The EMBO journal 24 (19), 3435-3445, 2005 | 124 | 2005 |
| In-depth profiling of the LiaR response of Bacillus subtilis D Wolf, F Kalamorz, T Wecke, A Juszczak, U Mäder, G Homuth, S Jordan, ... Journal of bacteriology 192 (18), 4680-4693, 2010 | 105 | 2010 |
| The tyrosine kinase McsB is a regulated adaptor protein for ClpCP J Kirstein, DA Dougan, U Gerth, M Hecker, K Turgay The EMBO Journal 26 (8), 2061-2070, 2007 | 86 | 2007 |
| Fine-tuning in regulation of Clp protein content in Bacillus subtilis U Gerth, J Kirstein, J Mostertz, T Waldminghaus, M Miethke, H Kock, ... Journal of Bacteriology 186 (1), 179-191, 2004 | 81 | 2004 |
| Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments J Kirstein, D Morito, T Kakihana, M Sugihara, A Minnen, MS Hipp, ... The EMBO journal 34 (18), 2334-2349, 2015 | 60 | 2015 |
| Localization of general and regulatory proteolysis in Bacillus subtilis cells J Kirstein, H Strahl, N Molière, LW Hamoen, K Turgay Molecular microbiology 70 (3), 682-694, 2008 | 57 | 2008 |
| Cyanobacterial ClpC/HSP100 protein displays intrinsic chaperone activity FI Andersson, R Blakytny, J Kirstein, K Turgay, B Bukau, A Mogk, ... Journal of Biological Chemistry 281 (9), 5468-5475, 2006 | 57 | 2006 |
| A new tyrosine phosphorylation mechanism involved in signal transduction in Bacillus subtilis J Kirstein, K Turgay Journal of molecular microbiology and biotechnology 9 (3-4), 182-188, 2005 | 51 | 2005 |
| Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex A Scior, A Buntru, K Arnsburg, A Ast, M Iburg, K Juenemann, ML Pigazzini, ... The EMBO journal 37 (2), 282-299, 2018 | 46 | 2018 |
| Caenorhabditis elegans as a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative … J Kirstein‐Miles, RI Morimoto Developmental dynamics: an official publication of the American Association …, 2010 | 40 | 2010 |
| Substrate recognition and processing by a Walker B mutant of the human mitochondrial AAA+ protein CLPX BR Lowth, J Kirstein-Miles, T Saiyed, H Brötz-Oesterhelt, RI Morimoto, ... Journal of structural biology 179 (2), 193-201, 2012 | 38 | 2012 |
| Reduced insulin/IGF-1 signaling restores the dynamic properties of key stress granule proteins during aging MC Lechler, ED Crawford, N Groh, K Widmaier, R Jung, J Kirstein, ... Cell reports 18 (2), 454-467, 2017 | 33 | 2017 |
| Function, evolution, and structure of J-domain proteins HH Kampinga, C Andreasson, A Barducci, ME Cheetham, D Cyr, ... Cell Stress and Chaperones 24 (1), 7-15, 2019 | 30 | 2019 |
Kürşad TurgayMax Planck Unit for the Science of Pathogens; Professor for Microbiology Leibniz University HannoverVerified email at mpusp.mpg.de
