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Yusuf Talha TAMER
Yusuf Talha TAMER
Principal Data and Applied Scientist @ Parkland Center for Clinical Innovation
Verified email at pccinnovation.org
Title
Cited by
Cited by
Year
Strength of selection pressure is an important parameter contributing to the complexity of antibiotic resistance evolution
T Oz, A Guvenek, S Yildiz, E Karaboga, YT Tamer, N Mumcuyan, VB Ozan, ...
Molecular biology and evolution 31 (9), 2387-2401, 2014
2742014
Sequence-specific targeting of bacterial resistance genes increases antibiotic efficacy
DH Ayhan, YT Tamer, M Akbar, SM Bailey, M Wong, SM Daly, ...
PLoS biology 14 (9), e1002552, 2016
902016
High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection
YT Tamer, IK Gaszek, H Abdizadeh, T Batur, K Reynolds, AR Atilgan, ...
Molecular Biology and Evolution 36 (7), 1533–1550, 2019
612019
A trimethoprim derivative impedes antibiotic resistance evolution
MS Manna, YT Tamer, I Gaszek, N Poulides, A Ahmed, X Wang, ...
Nature communications 12 (1), 2949, 2021
492021
Rapid ultrasensitive detection platform for antimicrobial susceptibility testing
MF Cansizoglu, YT Tamer, M Farid, AY Koh, E Toprak
PLoS biology 17 (5), e3000291, 2019
292019
Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance
H Abdizadeh, YT Tamer, O Acar, E Toprak, AR Atilgan, C Atilgan
Physical Chemistry Chemical Physics 19 (18), 11416-11428, 2017
292017
The antibiotic efflux protein TolC is a highly evolvable target under colicin E1 or TLS phage selection
YT Tamer, I Gaszek, M Rodrigues, FS Coskun, M Farid, AY Koh, W Russ, ...
Molecular biology and evolution 38 (10), 4493-4504, 2021
192021
Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo
H Peng, VQ Chau, W Phetsang, RM Sebastian, MRL Stone, S Datta, ...
Molecular Therapy-Methods & Clinical Development 15, 27-39, 2019
162019
On the race to starvation: how do bacteria survive high doses of antibiotics?
YT Tamer, E Toprak
Molecular cell 68 (6), 1019-1021, 2017
82017
Fourier transform infrared spectroscopy as a novel approach for analyzing the biochemical effects of anionic surfactants on a surfactant-degrading arcobacter butzleri strain
OF Sarioglu, YT Tamer, AD Ozkan, HI Atabay, C Molva, T Tekinay
Applied Spectroscopy 67 (4), 470-475, 2013
42013
Know Thy Patient: A Novel Approach and Method for Patient Segmentation and Clustering Using Machine Learning to Develop Holistic, Patient-Centered Programs and Treatment Plans
YT Tamer, A Karam, T Roderick, S Miff
NEJM Catalyst Innovations in Care Delivery 3 (4), 2022
32022
A synthetic knob for modulating antibiotic resistance
DH Ayhan, YT Tamer, M Akbar, DE Greenberg, E Toprak
Biophysical Journal 110 (3), 477a, 2016
32016
Patient Cluster Identification System and Method
Y Tamer, A Karam, S Miff, BA Moran, J Longo
US Patent App. 18/098,099, 2023
12023
Dynamical shifts in hydrogen bond occupancies identify mechanisms responsible for resistance conferring mutations
E Cetin, YT Tamer, E Toprak, AR Atilgan, C Atilgan
Biophysical Journal 121 (3), 455a-456a, 2022
12022
A rapid and highly sensitive optical platform for pathogen detection and antimicrobial sensitivity testing (Conference Presentation)
MF Cansizoglu, YT Tamer, M Farid, AY Koh, E Toprak
Optical Fibers and Sensors for Medical Diagnostics and Treatment …, 2020
2020
Exploiting Evolutionary Tradeoffs to Fight Evolution of Antibiotic Resistance
YT Tamer
2019
Molecular insights for resistance conferring mutations in competitive inhibition
H Abdizadeh, YT Tamer, E Toprak, AR Atilgan, C Atilgan
European biophysics journal with biophysics letters 46, S149-S149, 2017
2017
Quantifying the Molecular Constraints Driving the Trimethoprim Resistance in Escherichia Coli
YT Tamer, E Toprak
Biophysical Journal 110 (3), 397a, 2016
2016
Computational assessment of trimethoprim resistance in dihydrofolate reductase
H Abdizadeh, O Acar, TF Guclu, YT Tamer, TA Batur, E Toprak, AR Atilgan, ...
Biophysical Journal 110 (3), 47a-48a, 2016
2016
Studying genetic and enzymatic constraints driving evolution of antibiotic resistance
YT Tamer
2014
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