| Switch in site of inhibition: a strategy for structure-based discovery of human topoisomerase IIα catalytic inhibitors AT Baviskar, SM Amrutkar, N Trivedi, V Chaudhary, A Nayak, SK Guchhait, ... ACS medicinal chemistry letters 6 (4), 481-485, 2015 | 99 | 2015 |
| Nanoquinacrine induced apoptosis in cervical cancer stem cells through the inhibition of hedgehog-GLI1 cascade: Role of GLI-1 A Nayak, SR Satapathy, SS Dipon Das, N Tripathi, PV Bharatam, ... Scientific reports 6, 20600, 2016 | 55 | 2016 |
| Combretastatin A-4 inspired novel 2-aryl-3-arylamino-imidazo-pyridines/pyrazines as tubulin polymerization inhibitors, antimitotic and anticancer agents N Sanghai, V Jain, R Preet, S Kandekar, S Das, N Trivedi, P Mohapatra, ... MedChemComm 5 (6), 766-782, 2014 | 46 | 2014 |
| Quinacrine and curcumin synergistically increased the breast cancer stem cells death by inhibiting ABCG2 and modulating DNA damage repair pathway D Nayak, N Tripathi, D Kathuria, S Siddharth, A Nayak, PV Bharatam, ... The international journal of biochemistry & cell biology 119, 105682, 2020 | 35 | 2020 |
| Etoposide and doxorubicin enhance the sensitivity of triple negative breast cancers through modulation of TRAIL-DR5 axis S Das, N Tripathi, S Siddharth, A Nayak, D Nayak, C Sethy, PV Bharatam, ... Apoptosis 22, 1205-1224, 2017 | 33 | 2017 |
| Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade S Das, N Tripathi, R Preet, S Siddharth, A Nayak, PV Bharatam, ... Oncotarget 8 (1), 248-267, 2017 | 31 | 2017 |
| Identification of Guanosine 5′-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway Stanzin Angmo, Neha Tripathi, Sheenu Abbat, Shailesh Sharma, Shelley Sardul ... Scientific Reports 7, 40097, 2017 | 26 | 2017 |
| Assessing therapeutic potential of molecules: molecular property diagnostic suite for tuberculosis (MPDS TB) AS Gaur, A Bhardwaj, A Sharma, L John, MR Vivek, N Tripathi, ... Journal of Chemical Sciences 129 (5), 515-531, 2017 | 20 | 2017 |
| Mutational and Structural Analysis of Conserved Residues in Ribose-5-Phosphate Isomerase B from Leishmania donovani: Role in Substrate Recognition and … PK Kaur, N Tripathi, J Desale, S Neelagiri, S Yadav, PV Bharatam, ... PLoS One 11 (3), e0150764, 2016 | 18 | 2016 |
| Modeling the Closed and Open State Conformations of the GABAA Ion Channel - Plausible Structural Insights for Channel Gating RSK Vijayan, N Trivedi, SN Roy, I Bera, P Manoharan, PV Payghan, ... Journal of chemical information and modeling 52 (11), 2958-2969, 2012 | 15 | 2012 |
| Pharmacoinformatics analysis of merbarone binding site in human topoisomerase IIα N Tripathi, SK Guchhait, PV Bharatam Journal of Molecular Graphics and Modelling, https://doi.org/10.1016/j.jmgm …, 2018 | 10 | 2018 |
| Does N‐terminal huntingtin function as a ‘holdase’for inhibiting cellular protein aggregation? R Sethi, N Tripathi, AR Pallapati, A Gaikar, PV Bharatam, I Roy The FEBS journal, doi: 10.1111/febs.14457, 2018 | 7 | 2018 |
| Structural exploration of glutamine synthetase from Leishmania donovani: Insights from in silico and in vitro analysis V Kumar, NS Sri, N Tripathi, VK Sharma, PV Bharatam, P Garg, S Singh International journal of biological macromolecules 146, 860-874, 2020 | 6 | 2020 |
| Structural insights into the catalytic mechanism of granzyme B upon substrate and inhibitor binding N Tripathi, R Danger, M Chesneau, S Brouard, AD Laurent Journal of Molecular Graphics and Modelling 114, 108167, 2022 | 5 | 2022 |
| Investigation of phospholipase Cγ1 interaction with SLP76 using molecular modeling methods for identifying novel inhibitors N Tripathi, I Vetrivel, S Téletchéa, M Jean, P Legembre, AD Laurent International Journal of Molecular Sciences 20 (19), 4721, 2019 | 5 | 2019 |
| HToPred: A Tool for Human Topoisomerase II Inhibitor Prediction N Tripathi, N Shaikh, PV Bharatam, P Garg Molecular Informatics, https://doi.org/10.1002/minf.201800046, 2018 | 5 | 2018 |
| Structure-based identification of inhibitors disrupting the CD2–CD58 interactions N Tripathi, L Leherte, DP Vercauteren, AD Laurent Journal of computer-aided molecular design 35, 337-353, 2021 | 2 | 2021 |
| Chapter 2. Pharmacoinformatics Studies on Human Topoisomerase II: Exploring the Mechanism of Enzyme Inhibition N Tripathi, D R., SK Guchhait, PV Bharatam Topoisomerase inhibitors: Classification, mechanisms of action and adverse …, 2017 | 2 | 2017 |
| Amino-terminal wild type huntingtin as a protein folding aid-A function unexplored R Sethi, N Tripathi, PV Bharatam, I Roy FEBS JOURNAL 283, 105-105, 2016 | | 2016 |
Sankar K. GuchhaitNational Institute of Pharmaceutical Education and ResearchVerified email at niper.ac.in
