Synthesis, DNA binding, hemolysis assays and anticancer studies of copper (II), nickel (II) and iron (III) complexes of a pyrazoline-based ligand K Saleem, WA Wani, A Haque, MN Lone, MF Hsieh, MA Jairajpuri, I Ali Future medicinal chemistry 5 (2), 135-146, 2013 | 135 | 2013 |
Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment S Ashraf, H Kudo, J Rao, A Kikuchi, E Widmeier, JA Lawson, W Tan, ... Nature communications 9 (1), 1960, 2018 | 126 | 2018 |
Serpin inhibition mechanism: a delicate balance between native metastable state and polymerization MS Khan, P Singh, A Azhar, A Naseem, Q Rashid, MA Kabir, ... Journal of amino acids 2011 (1), 606797, 2011 | 112 | 2011 |
A genomic glimpse of aminoacyl-tRNA synthetases in malaria parasite Plasmodium falciparum TK Bhatt, C Kapil, S Khan, MA Jairajpuri, V Sharma, D Santoni, ... BMC genomics 10, 1-14, 2009 | 93 | 2009 |
Role of heparin and non heparin binding serpins in coagulation and angiogenesis: A complex interplay T Bhakuni, MF Ali, I Ahmad, S Bano, S Ansari, MA Jairajpuri Archives of biochemistry and biophysics 604, 128-142, 2016 | 67 | 2016 |
Antithrombin III phenylalanines 122 and 121 contribute to its high affinity for heparin and its conformational activation MA Jairajpuri, A Lu, U Desai, ST Olson, I Bjork, SC Bock Journal of Biological Chemistry 278 (18), 15941-15950, 2003 | 66 | 2003 |
Functional subunits of eukaryotic chaperonin CCT/TRiC in protein folding MA Kabir, W Uddin, A Narayanan, PK Reddy, MA Jairajpuri, F Sherman, ... Journal of amino acids 2011 (1), 843206, 2011 | 60 | 2011 |
Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant nephrotic syndrome J Rao, S Ashraf, W Tan, AT Van Der Ven, HY Gee, DA Braun, K Fehér, ... The Journal of Clinical Investigation 127 (12), 4257-4269, 2017 | 51 | 2017 |
Effect of novel triazole–amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies B Aneja, M Irfan, C Kapil, MA Jairajpuri, R Maguire, K Kavanagh, ... Organic & Biomolecular Chemistry 14 (45), 10599-10619, 2016 | 44 | 2016 |
Diketo acids and their amino acid/dipeptidic analogues as promising scaffolds for the development of bacterial methionine aminopeptidase inhibitors MM Masood, VK Pillalamarri, M Irfan, B Aneja, MA Jairajpuri, M Zafaryab, ... RSC Advances 5 (43), 34173-34183, 2015 | 28 | 2015 |
A structure guided drug-discovery approach towards identification of Plasmodium inhibitors B Aneja, B Kumar, MA Jairajpuri, M Abid RSC advances 6 (22), 18364-18406, 2016 | 26 | 2016 |
Elimination of P1 arginine 393 interaction with underlying glutamic acid 255 partially activates antithrombin III for thrombin inhibition but not factor Xa inhibition MA Jairajpuri, A Lu, SC Bock Journal of Biological Chemistry 277 (27), 24460-24465, 2002 | 25 | 2002 |
Antithrombotic potential of esculin 7, 3′, 4′, 5′, 6′-O-pentasulfate (EPS) for its role in thrombus reduction using rat thrombosis model I Ahmad, S Sharma, N Gupta, Q Rashid, M Abid, MZ Ashraf, MA Jairajpuri International journal of biological macromolecules 119, 360-368, 2018 | 22 | 2018 |
Antiangiogenic function of antithrombin is dependent on its conformational variation: implication for other serpins A Azhar, P Singh, Q Rashid, A Naseem, M Sazzad Khan, ... Protein and Peptide Letters 20 (4), 403-411, 2013 | 22 | 2013 |
Disruption of a tight cluster surrounding tyrosine 131 in the native conformation of antithrombin III activates it for factor Xa inhibition RGC dela Cruz, MA Jairajpuri, SC Bock Journal of Biological Chemistry 281 (42), 31668-31676, 2006 | 18 | 2006 |
Limitations of conventional anticoagulant therapy and the promises of non-heparin based conformational activators of antithrombin Q Rashid, P Singh, M Abid, MA Jairajpuri Journal of thrombosis and thrombolysis 34, 251-259, 2012 | 17 | 2012 |
Antithrombin III deficiency in Indian patients with deep vein thrombosis: identification of first India based AT variants including a novel point mutation (T280A) that leads to … T Bhakuni, A Sharma, Q Rashid, C Kapil, R Saxena, M Mahapatra, ... PLoS One 10 (3), e0121889, 2015 | 16 | 2015 |
Polysulfated trehalose as a novel anticoagulant agent with dual mode of action Q Rashid, M Abid, N Gupta, T Tyagi, MZ Ashraf, MA Jairajpuri BioMed Research International 2015 (1), 630482, 2015 | 16 | 2015 |
Inter-domain helix h10DOMI–h1DOMII is important in the molecular interaction of bovine serum albumin with curcumin: spectroscopic and computational analysis D Pangeni, C Kapil, MA Jairajpuri, P Sen European Biophysics Journal 44, 139-148, 2015 | 15 | 2015 |
Understanding the specificity of serpin–protease complexes through interface analysis Q Rashid, C Kapil, P Singh, V Kumari, MA Jairajpuri Journal of Biomolecular Structure and Dynamics 33 (6), 1352-1362, 2015 | 14 | 2015 |