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Sakthivel Sadayappan
Sakthivel Sadayappan
Professor of Internal Medicine at University of Cincinnati
Verified email at ucmail.uc.edu - Homepage
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Cited by
Cited by
Year
An acute immune response underlies the benefit of cardiac stem cell therapy
RJ Vagnozzi, M Maillet, MA Sargent, H Khalil, AKZ Johansen, ...
Nature 577 (7790), 405-409, 2020
4892020
A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia
PS Dhandapany, S Sadayappan, Y Xue, GT Powell, DS Rani, P Nallari, ...
Nature genetics 41 (2), 187-191, 2009
3302009
Phosphorylation and function of cardiac myosin binding protein-C in health and disease
D Barefield, S Sadayappan
Journal of molecular and cellular cardiology 48 (5), 866-875, 2010
3172010
Cardiac myosin-binding protein-C phosphorylation and cardiac function
S Sadayappan, J Gulick, H Osinska, LA Martin, HS Hahn, GW Dorn, ...
Circulation research 97 (11), 1156-1163, 2005
2792005
Cardiac myosin binding protein C phosphorylation is cardioprotective
S Sadayappan, H Osinska, R Klevitsky, JN Lorenz, M Sargent, ...
Proceedings of the National Academy of Sciences 103 (45), 16918-16923, 2006
2472006
Interleukin-10 treatment attenuates pressure overload–induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3 …
SK Verma, P Krishnamurthy, D Barefield, N Singh, R Gupta, E Lambers, ...
Circulation 126 (4), 418-429, 2012
2212012
Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations
V Sequeira, PJM Wijnker, LLAM Nijenkamp, DWD Kuster, A Najafi, ...
Circulation research 112 (11), 1491-1505, 2013
2182013
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin
CN Toepfer, H Wakimoto, AC Garfinkel, B McDonough, D Liao, J Jiang, ...
Science translational medicine 11 (476), eaat1199, 2019
1872019
Analysis of cardiac myosin binding protein-C phosphorylation in human heart muscle
S Sadayappan, AE Messer, GJM Steinen, J van der Velden, SB Marston
Journal of molecular and cellular cardiology 49 (6), 1003-1011, 2010
1612010
A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function
S Sadayappan, J Gulick, H Osinska, D Barefield, F Cuello, M Avkiran, ...
Circulation research 109 (2), 141-150, 2011
1562011
Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration
W Huang, Y Feng, J Liang, H Yu, C Wang, B Wang, M Wang, L Jiang, ...
Nature communications 9 (1), 700, 2018
1542018
Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function
SJ van Dijk, ER Paalberends, A Najafi, M Michels, S Sadayappan, ...
Circulation: Heart Failure 5 (1), 36-46, 2012
1522012
Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cycling
SC Bardswell, F Cuello, AJ Rowland, S Sadayappan, J Robbins, ...
Journal of Biological Chemistry 285 (8), 5674-5682, 2010
1402010
Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury
P Nicolaou, P Rodriguez, X Ren, X Zhou, J Qian, S Sadayappan, B Mitton, ...
Circulation research 104 (8), 1012-1020, 2009
1282009
Sarcomere mutation-specific expression patterns in human hypertrophic cardiomyopathy
AS Helms, FM Davis, D Coleman, SN Bartolone, AA Glazier, F Pagani, ...
Circulation: Cardiovascular Genetics 7 (4), 434-443, 2014
1182014
Cardiac myosin binding protein-C: redefining its structure and function
S Sadayappan, PP de Tombe
Biophysical reviews 4, 93-106, 2012
1132012
PKC-βII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144
H Wang, JE Grant, CM Doede, S Sadayappan, J Robbins, JW Walker
Journal of molecular and cellular cardiology 41 (5), 823-833, 2006
1132006
Cardiac myosin binding protein-C phosphorylation in a β-myosin heavy chain background
S Sadayappan, J Gulick, R Klevitsky, JN Lorenz, M Sargent, JD Molkentin, ...
Circulation 119 (9), 1253-1262, 2009
1092009
Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes
S Yasuda, P Coutu, S Sadayappan, J Robbins, JM Metzger
Circulation research 101 (4), 377-386, 2007
1082007
Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin
JW McNamara, RR Singh, S Sadayappan
Proceedings of the National Academy of Sciences 116 (24), 11731-11736, 2019
1032019
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