David A. Stoltz
David A. Stoltz
Professor of Medicine
Verified email at uiowa.edu
Title
Cited by
Cited by
Year
Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs
CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ...
Science 321 (5897), 1837-1841, 2008
7452008
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
AA Pezzulo, XX Tang, MJ Hoegger, MHA Alaiwa, S Ramachandran, ...
Nature 487 (7405), 109, 2012
6762012
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth
DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ...
Science translational medicine 2 (29), 29ra31-29ra31, 2010
4652010
Origins of cystic fibrosis lung disease
DA Stoltz, DK Meyerholz, MJ Welsh
New England Journal of Medicine 372 (4), 351-362, 2015
4612015
Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transfer
CS Rogers, Y Hao, T Rokhlina, M Samuel, DA Stoltz, Y Li, E Petroff, ...
The Journal of clinical investigation 118 (4), 1571-1577, 2008
4502008
IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines
P Schwarzenberger, V La Russa, A Miller, P Ye, W Huang, A Zieske, ...
The Journal of Immunology 161 (11), 6383-6389, 1998
3471998
Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis
MJ Hoegger, AJ Fischer, JD McMenimen, LS Ostedgaard, AJ Tucker, ...
Science 345 (6198), 818-822, 2014
2812014
The porcine lung as a potential model for cystic fibrosis
CS Rogers, WM Abraham, KA Brogden, JF Engelhardt, JT Fisher, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (2 …, 2008
2442008
Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia
JH Chen, DA Stoltz, PH Karp, SE Ernst, AA Pezzulo, TO Moninger, ...
Cell 143 (6), 911-923, 2010
2312010
Airway acidification initiates host defense abnormalities in cystic fibrosis mice
VS Shah, DK Meyerholz, XX Tang, L Reznikov, MA Alaiwa, SE Ernst, ...
Science 351 (6272), 503-507, 2016
2002016
The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis–like disease in pigs
LS Ostedgaard, DK Meyerholz, JH Chen, AA Pezzulo, PH Karp, ...
Science translational medicine 3 (74), 74ra24-74ra24, 2011
1902011
Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment
MP Rogan, DA Stoltz, DB Hornick
Chest 139 (6), 1480-1490, 2011
1702011
Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children
DK Meyerholz, DA Stoltz, E Namati, S Ramachandran, AA Pezzulo, ...
American journal of respiratory and critical care medicine 182 (10), 1251-1261, 2010
1652010
Acidic pH increases airway surface liquid viscosity in cystic fibrosis
XX Tang, LS Ostedgaard, MJ Hoegger, TO Moninger, PH Karp, ...
The Journal of clinical investigation 126 (3), 879-891, 2016
1642016
pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37
MHA Alaiwa, LR Reznikov, ND Gansemer, KA Sheets, AR Horswill, ...
Proceedings of the National Academy of Sciences 111 (52), 18703-18708, 2014
1402014
Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia
DA Stoltz, EA Ozer, CJ Ng, JM Yu, ST Reddy, AJ Lusis, N Bourquard, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (4 …, 2007
1372007
Pathology of gastrointestinal organs in a porcine model of cystic fibrosis
DK Meyerholz, DA Stoltz, AA Pezzulo, MJ Welsh
The American journal of pathology 176 (3), 1377-1389, 2010
1342010
Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections
KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ...
American journal of respiratory and critical care medicine 195 (12), 1617-1628, 2017
1122017
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs
DA Stoltz, T Rokhlina, SE Ernst, AA Pezzulo, LS Ostedgaard, PH Karp, ...
The Journal of clinical investigation 123 (6), 2685-2693, 2013
1052013
Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth
MP Rogan, LR Reznikov, AA Pezzulo, ND Gansemer, M Samuel, ...
Proceedings of the National Academy of Sciences 107 (47), 20571-20575, 2010
1042010
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