| Allosteric activation dictates PRC2 activity independent of its recruitment to chromatin CH Lee, JR Yu, S Kumar, Y Jin, G LeRoy, N Bhanu, S Kaneko, BA Garcia, ... Molecular cell 70 (3), 422-434. e6, 2018 | 122 | 2018 |
| Neomycin− neomycin dimer: an all-carbohydrate scaffold with high affinity for AT-rich DNA duplexes S Kumar, L Xue, DP Arya Journal of the American Chemical Society 133 (19), 7361-7375, 2011 | 82 | 2011 |
| Click dimers to target HIV TAR RNA conformation S Kumar, P Kellish, WE Robinson Jr, D Wang, DH Appella, DP Arya Biochemistry 51 (11), 2331-2347, 2012 | 75 | 2012 |
| Foldamer-mediated structural rearrangement attenuates Aβ oligomerization and cytotoxicity S Kumar, A Henning-Knechtel, I Chehade, M Magzoub, AD Hamilton Journal of the American Chemical Society 139 (47), 17098-17108, 2017 | 66 | 2017 |
| Aminoglycoside Binding to Oxytricha nova Telomeric DNA N Ranjan, KF Andreasen, S Kumar, D Hyde-Volpe, DP Arya Biochemistry 49 (45), 9891-9903, 2010 | 65 | 2010 |
| Foldamer-mediated manipulation of a pre-amyloid toxin S Kumar, M Birol, DE Schlamadinger, SP Wojcik, E Rhoades, ... Nature communications 7 (1), 11412, 2016 | 64 | 2016 |
| Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics S Kumar, DE Schlamadinger, MA Brown, JM Dunn, B Mercado, JA Hebda, ... Chemistry & biology 22 (3), 369-378, 2015 | 63 | 2015 |
| Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function L Palanikumar, L Karpauskaite, M Al-Sayegh, I Chehade, M Alam, ... Nature communications 12 (1), 3962, 2021 | 61 | 2021 |
| Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid M Birol, S Kumar, E Rhoades, AD Miranker Nature communications 9 (1), 1312, 2018 | 59 | 2018 |
| Probing the recognition surface of a DNA triplex: binding studies with intercalator− neomycin conjugates L Xue, H Xi, S Kumar, D Gray, E Davis, P Hamilton, M Skriba, DP Arya Biochemistry 49 (26), 5540-5552, 2010 | 57 | 2010 |
| Designed cell-penetrating peptide inhibitors of amyloid-beta aggregation and cytotoxicity A Henning-Knechtel, S Kumar, C Wallin, S Król, SKTS Wärmländer, ... Cell Reports Physical Science 1 (2), 2020 | 55 | 2020 |
| Recognition of HIV TAR RNA by triazole linked neomycin dimers S Kumar, DP Arya Bioorganic & medicinal chemistry letters 21 (16), 4788-4792, 2011 | 55 | 2011 |
| Molecular recognition of single-stranded RNA: Neomycin binding to poly (A) H Xi, D Gray, S Kumar, DP Arya FEBS letters 583 (13), 2269-2275, 2009 | 55 | 2009 |
| A foldamer approach to targeting membrane bound helical states of islet amyloid polypeptide S Kumar, AD Miranker Chemical Communications 49 (42), 4749-4751, 2013 | 54 | 2013 |
| Peptidomimetic-based multidomain targeting offers critical evaluation of Aβ structure and toxic function S Kumar, A Henning-Knechtel, M Magzoub, AD Hamilton Journal of the American Chemical Society 140 (21), 6562-6574, 2018 | 50 | 2018 |
| α-helix mimetics as modulators of Aβ self-assembly S Kumar, AD Hamilton Journal of the American Chemical Society 139 (16), 5744-5755, 2017 | 50 | 2017 |
| A fluorescence-based screen for ribosome binding antibiotics D Watkins, FA Norris, S Kumar, DP Arya Analytical biochemistry 434 (2), 300-307, 2013 | 50 | 2013 |
| Calorimetric and spectroscopic studies of aminoglycoside binding to AT-rich DNA triple helices H Xi, S Kumar, L Dosen-Micovic, DP Arya Biochimie 92 (5), 514-529, 2010 | 48 | 2010 |
| Recognition of HIV-TAR RNA using neomycin–benzimidazole conjugates N Ranjan, S Kumar, D Watkins, D Wang, DH Appella, DP Arya Bioorganic & medicinal chemistry letters 23 (20), 5689-5693, 2013 | 46 | 2013 |
| Multivalency in the recognition and antagonism of a HIV TAR RNA–TAT assembly using an aminoglycoside benzimidazole scaffold S Kumar, N Ranjan, P Kellish, C Gong, D Watkins, DP Arya Organic & biomolecular chemistry 14 (6), 2052-2056, 2016 | 42 | 2016 |
