Role of Smad proteins and transcription factor Sp1 in p21Waf1/Cip1 regulation by transforming growth factor-β K Pardali, A Kurisaki, A Moren, P Ten Dijke, D Kardassis, A Moustakas Journal of Biological Chemistry 275 (38), 29244-29256, 2000 | 523 | 2000 |
Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members A Moustakas, D Kardassis Proceedings of the National Academy of Sciences 95 (12), 6733-6738, 1998 | 436 | 1998 |
Transcriptional regulation of human apolipoprotein genes ApoB, ApoCIII, and ApoAII by members of the steroid hormone receptor superfamily HNF-4, ARP-1, EAR-2, and EAR-3. JA Ladias, M Hadzopoulou-Cladaras, D Kardassis, P Cardot, J Cheng, ... Journal of Biological Chemistry 267 (22), 15849-15860, 1992 | 388 | 1992 |
c-Jun transactivates the promoter of the human p21WAF1/Cip1 gene by acting as a superactivator of the ubiquitous transcription factor Sp1 D Kardassis, P Papakosta, K Pardali, A Moustakas Journal of Biological Chemistry 274 (41), 29572-29581, 1999 | 240 | 1999 |
Anti-tumor necrosis factor therapy improves insulin resistance, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance I Stagakis, G Bertsias, S Karvounaris, M Kavousanaki, D Virla, ... Arthritis research & therapy 14, 1-11, 2012 | 206 | 2012 |
Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21WAF1/Cip1 gene by the p53 tumor suppressor protein G Koutsodontis, I Tentes, P Papakosta, A Moustakas, D Kardassis Journal of Biological Chemistry 276 (31), 29116-29125, 2001 | 190 | 2001 |
Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus GK Bertsias, M Nakou, C Choulaki, A Raptopoulou, E Papadimitraki, ... Arthritis & Rheumatism 60 (1), 207-218, 2009 | 142 | 2009 |
HDL biogenesis, remodeling, and catabolism VI Zannis, P Fotakis, G Koukos, D Kardassis, C Ehnholm, M Jauhiainen, ... Handb Exp Pharmacol 224, 53-111, 2015 | 137 | 2015 |
Control of transforming growth factor β signal transduction by small GTPases D Kardassis, C Murphy, T Fotsis, A Moustakas, C Stournaras The FEBS journal 276 (11), 2947-2965, 2009 | 131 | 2009 |
Genetic mutations affecting human lipoproteins, their receptors, and their enzymes VI Zannis, D Kardassis, EE Zanni Advances in Human Genetics 21, 145-319, 1993 | 129 | 1993 |
Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition E Papadimitriou, E Vasilaki, C Vorvis, D Iliopoulos, A Moustakas, ... Oncogene 31 (23), 2862-2875, 2012 | 125 | 2012 |
Transcriptional regulation of the human apolipoprotein genes VI Zannis, HY Kan, A Kritis, E Zanni, D Kardassis Front Biosci 6 (3), d456-504, 2001 | 111 | 2001 |
A novel mechanism of TGFβ‐induced actin reorganization mediated by Smad proteins and Rho GTPases L Vardouli, E Vasilaki, E Papadimitriou, D Kardassis, C Stournaras The FEBS journal 275 (16), 4074-4087, 2008 | 104 | 2008 |
Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia B Wojciak-Stothard, L Zhao, E Oliver, O Dubois, Y Wu, D Kardassis, ... Circulation research 110 (11), 1423-1434, 2012 | 103 | 2012 |
Transcriptional regulatory mechanisms of the human apolipoprotein genes in vitro and in vivo VI Zannis, HY Kan, A Kritis, EE Zanni, D Kardassis Current opinion in lipidology 12 (2), 181-207, 2001 | 99 | 2001 |
Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved … G Koutsodontis, E Vasilaki, WC Chou, P Papakosta, D Kardassis Biochemical Journal 389 (2), 443-455, 2005 | 94 | 2005 |
Probing the pathways of chylomicron and HDL metabolism using adenovirus-mediated gene transfer VI Zannis, A Chroni, KE Kypreos, HY Kan, TB Cesar, EE Zanni, ... Current opinion in lipidology 15 (2), 151-166, 2004 | 93 | 2004 |
The role of Sp1 family members, the proximal GC-rich motifs, and the upstream enhancer region in the regulation of the human cell cycle inhibitor p21WAF-1/Cip1 gene promoter G Koutsodontis, A Moustakas, D Kardassis Biochemistry 41 (42), 12771-12784, 2002 | 92 | 2002 |
Cooperative binding of upstream stimulatory factor and hepatic nuclear factor 4 drives the transcription of the human apolipoprotein A-II gene A Ribeiro, D Pastier, D Kardassis, J Chambaz, P Cardot Journal of Biological Chemistry 274 (3), 1216-1225, 1999 | 89 | 1999 |
Mechanism of a Transcriptional Cross Talk between Transforming Growth Factor-β–regulated Smad3 and Smad4 Proteins and Orphan Nuclear Receptor Hepatocyte Nuclear Factor-4 WC Chou, V Prokova, K Shiraishi, U Valcourt, A Moustakas, ... Molecular biology of the cell 14 (3), 1279-1294, 2003 | 88 | 2003 |