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Thanga Mariappan
Thanga Mariappan
Lead Investigator
Verified email at syngeneintl.com
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Cited by
Year
A critical review of the probable reasons for the poor variable bioavailability of rifampicin from anti-tubercular fixed-dose combination (FDC) products, and the likely …
S Singh, TT Mariappan, R Shankar, N Sarda, B Singh
International journal of pharmaceutics 228 (1-2), 5-17, 2001
1432001
Regional gastrointestinal permeability of rifampicin and isoniazid (alone and their combination) in the rat
TT Mariappan, S Singh
The international Journal of Tuberculosis and Lung Disease 7 (8), 797-803, 2003
1142003
The reason for an increase in decomposition of rifampicin in the presence of isoniazid under acid conditions
S Singh, TT Mariappan, N Sharda, S Kumar, AK Chakraborti
Pharmacy and Pharmacology Communications 6 (9), 405-410, 2000
1012000
Selective IRAK4 inhibition attenuates disease in murine lupus models and demonstrates steroid sparing activity
S Dudhgaonkar, S Ranade, J Nagar, S Subramani, DS Prasad, ...
The Journal of Immunology 198 (3), 1308-1319, 2017
682017
The physical and chemical stability of anti-tuberculosis fixed-dose combination products under accelerated climatic conditions
H Bhutani, TT Mariappan, S Singh
The International Journal of Tuberculosis and Lung Disease 8 (9), 1073-1080, 2004
612004
Degradation of rifampicin, isoniazid and pyrazinamide from prepared mixtures and marketed single and combination products under acid conditions
S Singh, TT Mariappan, N SHARDA, B SINGH
Pharmacy and Pharmacology Communications 6 (11), 491-494, 2000
612000
Coproporphyrin-I: a fluorescent, endogenous optimal probe substrate for ABCC2 (MRP2) suitable for vesicle-based MRP2 inhibition assay
RR Gilibili, S Chatterjee, P Bagul, KW Mosure, BV Murali, TT Mariappan, ...
Drug Metabolism and Disposition 45 (6), 604-611, 2017
542017
Evidence of efflux-mediated and saturable absorption of rifampicin in rat intestine using the ligated loop and everted gut sac techniques
TT Mariappan, S Singh
Molecular pharmaceutics 1 (5), 363-367, 2004
512004
Evidence for the validity of pyridoxic acid (PDA) as a plasma-based endogenous probe for OAT1 and OAT3 function in healthy subjects
H Shen, VK Holenarsipur, TT Mariappan, DM Drexler, JL Cantone, ...
Journal of Pharmacology and Experimental Therapeutics 368 (1), 136-145, 2019
422019
Behavior of uptake of moisture by drugs and excipients under accelerated conditions of temperature and humidity in the absence and the presence of light. 1. Pure anti …
S Singh, H Bhutani, TT Mariappan, H Kaur, M Bajaj, SP Pakhale
International journal of pharmaceutics 245 (1-2), 37-44, 2002
412002
Insight into tissue unbound concentration: utility in drug discovery and development
T Thanga Mariappan, S Mandlekar, P Marathe
Current drug metabolism 14 (3), 324-340, 2013
382013
Endogenous biomarkers to assess drug-drug interactions by drug transporters and enzymes
TT Mariappan, H Shen, P Marathe
Current Drug Metabolism 18 (8), 757-768, 2017
332017
Overestimation of rifampicin during colorimetric analysis of anti-tuberculosis products containing isoniazid due to formation of isonicotinyl hydrazone
TT Mariappan, KC Jindal, S Singh
Journal of pharmaceutical and biomedical analysis 36 (4), 905-908, 2004
312004
Behavior of moisture gain and equilibrium moisture contents (EMC) of various drug substances and correlation with compendial information on hygroscopicity and loss on drying
NA Visalakshi, TT Mariappan, H Bhutani, S Singh
Pharmaceutical development and technology 10 (4), 489-497, 2005
282005
An explanation for the physical instability of a marketed fixed dose combination (FDC) formulation containing isoniazid and ethambutol and proposed solutions
H Bhutani, TT Mariappan, S Singh
Drug development and industrial pharmacy 30 (6), 667-672, 2004
282004
A Validated Reversed‐Phase (C18) HPLC Method for Simultaneous Determination of Rifampicin, Isoniazid and Pyrazinamide in USP Dissolution Medium and …
TT Mariappan, B SINGH, S SINGH
Pharmacy and Pharmacology Communications 6 (8), 345-349, 2000
282000
A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics
V Kurawattimath, K Pocha, T Thanga Mariappan, RK Trivedi, S Mandlekar
European journal of drug metabolism and pharmacokinetics 37, 23-30, 2012
262012
Positioning of rifampicin in the biopharmaceutics classification system (BCS)
TT Mariappan, S Singh
Clinical Research and Regulatory Affairs 23 (1), 1-10, 2006
252006
Quality problems of anti-tuberculosis Fixed-dose Combinations (FDCS) A way forward.
S Singh, H Bhutani, TT Mariappan
252006
Behavior of uptake of moisture by drugs and excipients under accelerated conditions of temperature and humidity in the absence and the presence of light-Part II: Packaged and …
H Bhutani, TT Mariappan, S Singh
Pharmaceutical Technology 27 (6), 44-44, 2003
242003
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