A validated 1H NMR method for the determination of the degree of deacetylation of chitosan M Lavertu, Z Xia, AN Serreqi, M Berrada, A Rodrigues, D Wang, ... Journal of pharmaceutical and biomedical analysis 32 (6), 1149-1158, 2003 | 741 | 2003 |
High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation M Lavertu, S Methot, N Tran-Khanh, MD Buschmann Biomaterials 27 (27), 4815-4824, 2006 | 568 | 2006 |
Chitosans for delivery of nucleic acids MD Buschmann, A Merzouki, M Lavertu, M Thibault, M Jean, V Darras Advanced drug delivery reviews 65 (9), 1234-1270, 2013 | 266 | 2013 |
Ionization behavior of chitosan and chitosan–DNA polyplexes indicate that chitosan has a similar capability to induce a proton-sponge effect as PEI I Richard, M Thibault, G De Crescenzo, MD Buschmann, M Lavertu Biomacromolecules 14 (6), 1732-1740, 2013 | 190 | 2013 |
New Insights into chitosan− DNA interactions using isothermal titration microcalorimetry PL Ma, M Lavertu, FM Winnik, MD Buschmann Biomacromolecules 10 (6), 1490-1499, 2009 | 188 | 2009 |
Ionization and solubility of chitosan solutions related to thermosensitive chitosan/glycerol-phosphate systems D Filion, M Lavertu, MD Buschmann Biomacromolecules 8 (10), 3224-3234, 2007 | 161 | 2007 |
Heat-induced transfer of protons from chitosan to glycerol phosphate produces chitosan precipitation and gelation M Lavertu, D Filion, MD Buschmann Biomacromolecules 9 (2), 640-650, 2008 | 142 | 2008 |
Enhanced gene delivery mediated by low molecular weight chitosan/DNA complexes: effect of pH and serum S Nimesh, MM Thibault, M Lavertu, MD Buschmann Molecular biotechnology 46, 182-196, 2010 | 136 | 2010 |
Intracellular trafficking and decondensation kinetics of chitosan–pDNA polyplexes M Thibault, S Nimesh, M Lavertu, MD Buschmann Molecular Therapy 18 (10), 1787-1795, 2010 | 125 | 2010 |
siRNA delivery with chitosan: influence of chitosan molecular weight, degree of deacetylation, and amine to phosphate ratio on in vitro silencing efficiency, hemocompatibility … M Alameh, M Lavertu, N Tran-Khanh, CY Chang, F Lesage, M Bail, ... Biomacromolecules 19 (1), 112-131, 2018 | 117 | 2018 |
Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes M Thibault, M Astolfi, N Tran-Khanh, M Lavertu, V Darras, A Merzouki, ... Biomaterials 32 (20), 4639-4646, 2011 | 107 | 2011 |
Low molecular weight chitosan nanoparticulate system at low N: P ratio for nontoxic polynucleotide delivery M Alameh, D DeJesus, M Jean, V Darras, M Thibault, M Lavertu, ... International journal of nanomedicine, 1399-1414, 2012 | 105 | 2012 |
Chitosan–plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies M Jean, F Smaoui, M Lavertu, S Methot, L Bouhdoud, MD Buschmann, ... Gene therapy 16 (9), 1097-1110, 2009 | 103 | 2009 |
Precise derivatization of structurally distinct chitosans with rhodamine B isothiocyanate O Ma, M Lavertu, J Sun, S Nguyen, MD Buschmann, FM Winnik, ... Carbohydrate polymers 72 (4), 616-624, 2008 | 98 | 2008 |
Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes M Jean, M Alameh, D De Jesus, M Thibault, M Lavertu, V Darras, M Nelea, ... European Journal of Pharmaceutical Sciences 45 (1-2), 138-149, 2012 | 91 | 2012 |
Vaccine technologies and platforms for infectious diseases: Current progress, challenges, and opportunities M Ghattas, G Dwivedi, M Lavertu, MG Alameh Vaccines 9 (12), 1490, 2021 | 82 | 2021 |
Lysosomal rupture induced by structurally distinct chitosans either promotes a type 1 IFN response or activates the inflammasome in macrophages D Fong, P Grégoire-Gélinas, AP Cheng, T Mezheritsky, M Lavertu, S Sato, ... Biomaterials 129, 127-138, 2017 | 65 | 2017 |
Kinetics and efficiency of chitosan reacetylation M Lavertu, V Darras, MD Buschmann Carbohydrate polymers 87 (2), 1192-1198, 2012 | 53 | 2012 |
Composition and method for efficient delivery of nucleic acids to cells using chitosan MD Buschmann, M Lavertu, S Methot US Patent App. 12/092,498, 2009 | 43 | 2009 |
Lyophilisation and concentration of chitosan/siRNA polyplexes: Influence of buffer composition, oligonucleotide sequence, and hyaluronic acid coating D Veilleux, RKG Panicker, A Chevrier, K Biniecki, M Lavertu, ... Journal of colloid and interface science 512, 335-345, 2018 | 38 | 2018 |