| Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors H Sharma, S Patil, TW Sanchez, N Neamati, RF Schinazi, JK Buolamwini Bioorganic & medicinal chemistry 19 (6), 2030-2045, 2011 | 126 | 2011 |
| Functionalized graphene oxide for chemotherapeutic drug delivery and cancer treatment: a promising material in nanomedicine H Sharma, S Mondal International Journal of Molecular Sciences 21 (17), 6280, 2020 | 117 | 2020 |
| The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models W Wang, JJ Qin, S Voruganti, KS Srivenugopal, S Nag, S Patil, H Sharma, ... Nature communications 5 (1), 5086, 2014 | 92 | 2014 |
| Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice W Wang, JJ Qin, S Voruganti, MH Wang, H Sharma, S Patil, J Zhou, ... Gastroenterology 147 (4), 893-902. e2, 2014 | 78 | 2014 |
| JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21 X Yang, W Wang, JJ Qin, MH Wang, H Sharma, JK Buolamwini, H Wang, ... Plos one 7 (4), e34303, 2012 | 53 | 2012 |
| Triple reuptake inhibitors as potential next-generation antidepressants: a new hope? H Sharma, S Santra, A Dutta Future medicinal chemistry 7 (17), 2385-2406, 2015 | 51 | 2015 |
| Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors H Sharma, TW Sanchez, N Neamati, M Detorio, RF Schinazi, X Cheng, ... Bioorganic & medicinal chemistry letters 23 (22), 6146-6151, 2013 | 50 | 2013 |
| Development of GLUT4-selective antagonists for multiple myeloma therapy C Wei, R Bajpai, H Sharma, M Heitmeier, AD Jain, SM Matulis, AK Nooka, ... European journal of medicinal chemistry 139, 573-586, 2017 | 49 | 2017 |
| Development of novel therapeutics targeting isocitrate dehydrogenase mutations in cancer H Sharma Current Topics in Medicinal Chemistry 18 (6), 505-524, 2018 | 35 | 2018 |
| Novel multifunctional dopamine D2/D3 receptors agonists with potential neuroprotection and anti-alpha synuclein protein aggregation properties D Luo, H Sharma, D Yedlapudi, T Antonio, MEA Reith, AK Dutta Bioorganic & medicinal chemistry 24 (21), 5088-5102, 2016 | 26 | 2016 |
| Homology model-guided 3D-QSAR studies of HIV-1 integrase inhibitors H Sharma, X Cheng, JK Buolamwini Journal of chemical information and modeling 52 (2), 515-544, 2012 | 26 | 2012 |
| Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S, 6S)-6-benzhydryltetrahydro-2H-pyran-3-yl) amino) methyl) phenol: Synthesis, biological characterization … H Sharma, S Santra, J Debnath, T Antonio, M Reith, A Dutta Bioorganic & medicinal chemistry 22 (1), 311-324, 2014 | 19 | 2014 |
| Development and validation of a rapid HPLC method for quantitation of SP‐141, a novel pyrido [b] indole anticancer agent, and an initial pharmacokinetic study in mice S Nag, JJ Qin, S Voruganti, MH Wang, H Sharma, S Patil, JK Buolamwini, ... Biomedical Chromatography 29 (5), 654-663, 2015 | 14 | 2015 |
| Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters AK Dutta, S Santra, H Sharma, C Voshavar, L Xu, O Mabrouk, T Antonio, ... PloS one 9 (11), e113420, 2014 | 12 | 2014 |
| 1-aryl Or 1-heteroaryl-pyrido[b]indoles And Uses Thereof JK Buolamwini, S Patil, H Sharma, JK Addo WO Patent WO 2010/123583 A3, 2011 | 8* | 2011 |
| New NSAID conjugates as potent and selective COX-2 inhibitors: Synthesis, molecular modeling and biological investigation RM Bokhtia, SS Panda, AS Girgis, N Samir, MF Said, A Abdelnaser, ... Molecules 28 (4), 1945, 2023 | 7 | 2023 |
| Understanding the structural requirements of hybrid (S)-6-((2-(4-phenylpiperazin-1-yl) ethyl)(propyl) amino)-5, 6, 7, 8-tetrahydronaphthalen-1-ol and its analogs as D2/D3 … G Modi, H Sharma, PS Kharkar, AK Dutta Medchemcomm 5 (9), 1384-1399, 2014 | 7 | 2014 |
| Development of potent dopamine–norepinephrine uptake inhibitors (DNRIs) based on a (2S, 4R, 5R)-2-benzhydryl-5-((4-methoxybenzyl) amino) tetrahydro-2H-pyran-4-ol molecular template S Santra, H Sharma, S Vedachalam, T Antonio, M Reith, A Dutta Bioorganic & medicinal chemistry 23 (4), 821-828, 2015 | 6 | 2015 |
| Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons Y Han, ID Iyamu, MR Clutter, RK Mishra, KA Lyman, C Zhou, I Michailidis, ... Journal of Biological Chemistry 298 (7), 2022 | 3 | 2022 |
| l-ARYL- 0R l-HETEROARYL-PYRIDO[B]INDOLES AND USES THEREOF IN TREATING CANCERS JK Buolamwini, S Patil, H Sharma, JK Addo US Patent US 8,329,723 B2, 2012 | 2 | 2012 |
