Fibril structure of amyloid-β (1–42) by cryo–electron microscopy L Gremer, D Schölzel, C Schenk, E Reinartz, J Labahn, RBG Ravelli, ... Science 358 (6359), 116-119, 2017 | 930 | 2017 |
Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster H Dobbek, V Svetlitchnyi, L Gremer, R Huber, O Meyer Science 293 (5533), 1281-1285, 2001 | 639 | 2001 |
Catalysis at a dinuclear [CuSMo (O) OH] cluster in a CO dehydrogenase resolved at 1.1-Å resolution H Dobbek, L Gremer, R Kiefersauer, R Huber, O Meyer Proceedings of the National Academy of Sciences 99 (25), 15971-15976, 2002 | 414 | 2002 |
A restricted spectrum of NRAS mutations causes Noonan syndrome IC Cirstea, K Kutsche, R Dvorsky, L Gremer, C Carta, D Horn, AE Roberts, ... Nature genetics 42 (1), 27-29, 2010 | 350 | 2010 |
Crystal structure and mechanism of CO dehydrogenase, a molybdo iron-sulfur flavoprotein containing S-selanylcysteine H Dobbek, L Gremer, O Meyer, R Huber Proceedings of the National Academy of Sciences 96 (16), 8884-8889, 1999 | 314 | 1999 |
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo SA Ismail, YX Chen, A Rusinova, A Chandra, M Bierbaum, L Gremer, ... Nature chemical biology 7 (12), 942-949, 2011 | 296 | 2011 |
Rho-kinase: regulation,(dys) function, and inhibition E Amin, BN Dubey, SC Zhang, L Gremer, R Dvorsky, JM Moll, MS Taha, ... Biological chemistry 394 (11), 1399-1410, 2013 | 199 | 2013 |
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders L Gremer, T Merbitz‐Zahradnik, R Dvorsky, IC Cirstea, CP Kratz, ... Human mutation 32 (1), 33-43, 2011 | 161 | 2011 |
A novel free-mounting system for protein crystals: transformation and improvement of diffraction power by accurately controlled humidity changes R Kiefersauer, ME Than, H Dobbek, L Gremer, M Melero, S Strobl, ... Journal of applied crystallography 33 (5), 1223-1230, 2000 | 151 | 2000 |
Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils C Röder, T Kupreichyk, L Gremer, LU Schäfer, KR Pothula, RBG Ravelli, ... Nature structural & molecular biology 27 (7), 660-667, 2020 | 125 | 2020 |
A novel binuclear [CuSMo] cluster at the active site of carbon monoxide dehydrogenase: characterization by X-ray absorption spectroscopy M Gnida, R Ferner, L Gremer, O Meyer, W Meyer-Klaucke Biochemistry 42 (1), 222-230, 2003 | 124 | 2003 |
Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes IC Rosnizeck, T Graf, M Spoerner, J Tränkle, D Filchtinski, C Herrmann, ... Angewandte Chemie International Edition 49 (22), 3830-3833, 2010 | 121 | 2010 |
Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3–induced outside-in signaling and clusterin release L Donner, K Fälker, L Gremer, S Klinker, G Pagani, LU Ljungberg, ... Science signaling 9 (429), ra52-ra52, 2016 | 110 | 2016 |
The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction V Pena, M Hothorn, A Eberth, N Kaschau, A Parret, L Gremer, F Bonneau, ... EMBO reports 9 (4), 350-355, 2008 | 107 | 2008 |
A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family A Eberth, R Lundmark, L Gremer, R Dvorsky, KT Koessmeier, ... Biochemical Journal 417 (1), 371-379, 2009 | 103 | 2009 |
The effect of intracellular molybdenum in Hydrogenophaga pseudoflava on the crystallographic structure of the seleno-molybdo-iron-sulfur flavoenzyme carbon monoxide dehydrogenase P Hänzelmann, H Dobbek, L Gremer, R Huber, O Meyer Journal of molecular biology 301 (5), 1221-1235, 2000 | 101 | 2000 |
The role of Se, Mo and Fe in the structure and function of carbon monoxide dehydrogenase O Meyer, L Gremer, R Ferner, M Ferner, H Dobbek, M Gnida, ... Walter de Gruyter 381 (9-10), 865-876, 2000 | 99 | 2000 |
Origin of metastable oligomers and their effects on amyloid fibril self-assembly F Hasecke, T Miti, C Perez, J Barton, D Schölzel, L Gremer, CSR Grüning, ... Chemical science 9 (27), 5937-5948, 2018 | 93 | 2018 |
Synthesis of the Rheb and K‐Ras4B GTPases YX Chen, S Koch, K Uhlenbrock, K Weise, D Das, L Gremer, L Brunsveld, ... Angewandte Chemie International Edition 49 (35), 6090-6095, 2010 | 90 | 2010 |
Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange … M Jaiswal, L Gremer, R Dvorsky, LC Haeusler, IC Cirstea, K Uhlenbrock, ... Journal of Biological Chemistry 286 (20), 18202-18212, 2011 | 81 | 2011 |