Andrew Seeber
Andrew Seeber
Transition Bio Inc
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Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates
MH Hauer, A Seeber, V Singh, R Thierry, R Sack, A Amitai, ...
Nature structural & molecular biology 24 (2), 99-107, 2017
Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage
A Seeber, V Dion, SM Gasser
Genes & development 27 (18), 1999-2008, 2013
Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress
J Poli, CB Gerhold, A Tosi, N Hustedt, A Seeber, R Sack, F Herzog, ...
Genes & development 30 (3), 337-354, 2016
Visualization of chromatin decompaction and break site extrusion as predicted by statistical polymer modeling of single-locus trajectories
A Amitai, A Seeber, SM Gasser, D Holcman
Cell reports 18 (5), 1200-1214, 2017
Nucleosome remodelers in double-strand break repair
A Seeber, M Hauer, SM Gasser
Current opinion in genetics & development 23 (2), 174-184, 2013
Cohesin and the nucleolus constrain the mobility of spontaneous repair foci
V Dion, V Kalck, A Seeber, T Schleker, SM Gasser
EMBO reports 14 (11), 984-991, 2013
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks
K Shimada, I Filipuzzi, M Stahl, SB Helliwell, C Studer, D Hoepfner, ...
Molecular cell 51 (6), 829-839, 2013
Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei
DS Cabianca, C Muñoz-Jiménez, V Kalck, D Gaidatzis, J Padeken, ...
Nature 569 (7758), 734-739, 2019
Chromatin organization and dynamics in double-strand break repair
A Seeber, SM Gasser
Current opinion in genetics & development 43, 9-16, 2017
Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling
N Hustedt, A Seeber, R Sack, M Tsai-Pflugfelder, B Bhullar, H Vlaming, ...
Molecular cell 57 (2), 273-289, 2015
Chromosome dynamics in response to DNA damage
A Seeber, MH Hauer, SM Gasser
Annual review of genetics 52, 295-319, 2018
Structural basis of Mec1-Ddc2-RPA assembly and activation on single-stranded DNA at sites of damage
I Deshpande, A Seeber, K Shimada, JJ Keusch, H Gut, SM Gasser
Molecular cell 68 (2), 431-445. e5, 2017
RPA mediates recruitment of MRX to forks and double-strand breaks to hold sister chromatids together
A Seeber, AM Hegnauer, N Hustedt, I Deshpande, J Poli, J Eglinger, ...
Molecular cell 64 (5), 951-966, 2016
Monitoring the spatio-temporal organization and dynamics of the genome
HA Shaban, A Seeber
Nucleic acids research 48 (7), 3423-3434, 2020
Advances in chromatin and chromosome research: perspectives from multiple fields
AA Agbleke, A Amitai, JD Buenrostro, A Chakrabarti, L Chu, AS Hansen, ...
Molecular cell 79 (6), 881-901, 2020
DNA damage-induced nucleosome depletion enhances homology search independently of local break movement
A Cheblal, K Challa, A Seeber, K Shimada, H Yoshida, HC Ferreira, ...
Molecular cell 80 (2), 311-326. e4, 2020
Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair
K Challa, CD Schmid, S Kitagawa, A Cheblal, V Iesmantavicius, A Seeber, ...
Molecular Cell 81 (4), 811-829. e6, 2021
Advances using single-particle trajectories to reconstruct chromatin organization and dynamics
O Shukron, A Seeber, A Amitai, D Holcman
Trends in Genetics 35 (9), 685-705, 2019
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry
J Chen, SM Young, C Allen, A Seeber, MP Péli-Gulli, N Panchaud, ...
ACS chemical biology 7 (4), 715-722, 2012
Asymmetric processing of DNA ends at a double-strand break leads to unconstrained dynamics and ectopic translocation
I Marcomini, K Shimada, N Delgoshaie, I Yamamoto, A Seeber, A Cheblal, ...
Cell reports 24 (10), 2614-2628. e4, 2018
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