| Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity M Mack, B Luckow, PJ Nelson, J Cihak, G Simmons, PR Clapham, ... The Journal of experimental medicine 187 (8), 1215-1224, 1998 | 521 | 1998 |
| Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4 N Signoret, J Oldridge, A Pelchen-Matthews, PJ Klasse, T Tran, LF Brass, ... The Journal of cell biology 139 (3), 651-664, 1997 | 479 | 1997 |
| Endocytosis and recycling of the HIV coreceptor CCR5 N Signoret, A Pelchen-Matthews, M Mack, AEI Proudfoot, M Marsh The Journal of cell biology 151 (6), 1281-1294, 2000 | 243 | 2000 |
| Differential regulation of CXCR4 and CCR5 endocytosis N Signoret, MM Rosenkilde, PJ Klasse, TW Schwartz, MH Malim, ... Journal of cell science 111 (18), 2819-2830, 1998 | 174 | 1998 |
| Mechanisms regulating chemokine receptor activity LD Bennett, JM Fox, N Signoret Immunology 134 (3), 246-256, 2011 | 133 | 2011 |
| B cell antigen receptor engagement inhibits stromal cell–derived factor (SDF)-1α chemotaxis and promotes protein kinase C (PKC)-induced internalization of CXCR4 R Guinamard, N Signoret, M Ishiai, M Marsh, T Kurosaki, JV Ravetch The Journal of experimental medicine 189 (9), 1461-1466, 1999 | 131 | 1999 |
| Antisense oligonucleotides in solution or encapsulated in immunoliposomes inhibit replication of HIV-1 by several different mechanisms O Zelphati, JL Imbach, N Signoret, G Zon, B Rayner, L Leserman Nucleic acids research 22 (20), 4307-4314, 1994 | 122 | 1994 |
| Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent N Signoret, L Hewlett, S Wavre, A Pelchen-Matthews, M Oppermann, ... Molecular biology of the cell 16 (2), 902-917, 2005 | 112 | 2005 |
| Class I major histocompatibility complex-restricted cytotoxic T lymphocytes specific for Epstein-Barr virus (EBV)-transformed B lymphoblastoid cell lines against which they … AB Hill, SP Lee, JS Haurum, N Murray, QY Yao, M Rowe, N Signoret, ... The Journal of experimental medicine 181 (6), 2221-2228, 1995 | 109 | 1995 |
| Chemokine receptor trafficking and viral replication A Pelchen‐Matthews, N Signoret, PJ Klasse, A Fraile‐Ramos, M Marsh Immunological reviews 168 (1), 33-49, 1999 | 102 | 1999 |
| Dishevelled (Dvl-2) activates canonical Wnt signalling in the absence of cytoplasmic puncta MJ Smalley, N Signoret, D Robertson, A Tilley, A Hann, K Ewan, Y Ding, ... Journal of cell science 118 (22), 5279-5289, 2005 | 89 | 2005 |
| Innate Killing of Leishmania donovani by Macrophages of the Splenic Marginal Zone Requires IRF-7 R Phillips, M Svensson, N Aziz, A Maroof, N Brown, L Beattie, N Signoret, ... PLoS pathogens 6 (3), e1000813, 2010 | 67 | 2010 |
| Lack of p56 lck expression correlates with CD4 endocytosis in primary lymphoid and myeloid cells A Pelchen‐Matthews, RP da Silva, MJ Bijlmakers, N Signoret, S Gordon, ... European journal of immunology 28 (11), 3639-3647, 1998 | 58 | 1998 |
| Transduction of activation signal that follows HIV-1 binding to CD4 and CD4 dimerization involves the immunoglobulin CDR3-like region in domain 1 of CD4 L Briant, N Signoret, M Gaubin, V Robert-Hebmann, X Zhang, R Murali, ... Journal of Biological Chemistry 272 (31), 19441-19450, 1997 | 48 | 1997 |
| Factors involved in entry of the human immunodeficiency virus type 1 into permissive cells: lack of evidence of a role for CD26 I Lazaro, D Naniche, N Signoret, AM Bernard, D Marguet, D Klatzmann, ... Journal of virology 68 (10), 6535-6546, 1994 | 43 | 1994 |
| Human and simian immunodeficiency viruses: virus-receptor interactions N Signoret, P Poignard, D Blanc, QJ Sattentau Trends in microbiology 1 (9), 328-333, 1993 | 37 | 1993 |
| pH‐independent endocytic cycling of the chemokine receptor CCR5 N Signoret, T Christophe, M Oppermann, M Marsh Traffic 5 (7), 529-543, 2004 | 35 | 2004 |
| TLR2-dependent pathway of heterologous down-modulation for the CC chemokine receptors 1, 2, and 5 in human blood monocytes JM Fox, E Letellier, CJ Oliphant, N Signoret Blood, The Journal of the American Society of Hematology 117 (6), 1851-1860, 2011 | 31 | 2011 |
| Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19 JC Wilson, D Kealy, SR James, T Plowman, K Newling, C Jagger, ... IScience 25 (1), 2022 | 29 | 2022 |
| CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells JM Fox, R Kasprowicz, O Hartley, N Signoret Journal of Leucocyte Biology 98 (1), 59-71, 2015 | 28 | 2015 |
PJ KlasseProfessor of Microbiology and Immunology, Cornell UniversityVerified email at med.cornell.edu
