Identification, biochemical and structural evaluation of species-specific inhibitors against type I methionine aminopeptidases C Kishor, T Arya, R Reddi, X Chen, V Saddanapu, AK Marapaka, ... Journal of medicinal chemistry 56 (13), 5295-5305, 2013 | 33 | 2013 |
Identification of the molecular basis of inhibitor selectivity between the human and streptococcal type I methionine aminopeptidases T Arya, R Reddi, C Kishor, RJ Ganji, S Bhukya, R Gumpena, S McGowan, ... Journal of medicinal chemistry 58 (5), 2350-2357, 2015 | 24 | 2015 |
Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2, 2′-bipyridine based inhibitors C Kishor, R Gumpena, R Reddi, A Addlagatta MedChemComm 3 (11), 1406-1412, 2012 | 22 | 2012 |
Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N RJ Ganji, R Reddi, R Gumpena, AK Marapaka, T Arya, P Sankoju, ... Protein Science 24 (5), 823-831, 2015 | 19 | 2015 |
Glu121‐Lys319 salt bridge between catalytic and N‐terminal domains is pivotal for the activity and stability of Escherichia coli aminopeptidase N R Gumpena, C Kishor, RJ Ganji, N Jain, A Addlagatta Protein science 21 (5), 727-736, 2012 | 19 | 2012 |
Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents R Reddi, T Arya, C Kishor, R Gumpena, RJ Ganji, S Bhukya, A Addlagatta The FEBS Journal 281 (18), 4240-4248, 2014 | 14 | 2014 |
Discovery of α, β‐and α, γ‐Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases R Gumpena, C Kishor, RJ Ganji, A Addlagatta ChemMedChem 6 (11), 1971-1976, 2011 | 14 | 2011 |
Dual glycolate oxidase/lactate dehydrogenase A inhibitors for primary hyperoxaluria J Ding, R Gumpena, MO Boily, A Caron, O Chong, JH Cox, V Dumais, ... ACS Medicinal Chemistry Letters 12 (7), 1116-1123, 2021 | 13 | 2021 |
Specificity of human sulfiredoxin for reductant and peroxiredoxin oligomeric state TE Forshaw, JA Reisz, KJ Nelson, R Gumpena, JR Lawson, TJ Jönsson, ... Antioxidants 10 (6), 946, 2021 | 11 | 2021 |
Crystal structure of the human dual specificity phosphatase 1 catalytic domain R Gumpena, GT Lountos, S Raran‐Kurussi, JE Tropea, S Cherry, ... Protein Science 27 (2), 561-567, 2018 | 11 | 2018 |
MBP-binding DARPins facilitate the crystallization of an MBP fusion protein R Gumpena, GT Lountos, DS Waugh Acta Crystallographica Section F: Structural Biology Communications 74 (9 …, 2018 | 7 | 2018 |
Discovery, structural and biochemical studies of a rare Glu/Asp specific M1 class aminopeptidase from Legionella pneumophila AK Marapaka, V Pillalamarri, R Gumpena, N Haque, SC Bala, A Jangam, ... International journal of biological macromolecules 120, 1111-1118, 2018 | 6 | 2018 |
Small Molecule TREX1 Inhibitors as Novel Immunotherapies W Hemphill, S Harvey, R Gumpena, S Simpson, J Grayson, T Smalley, ... The FASEB Journal 34 (S1), 1-1, 2020 | 5 | 2020 |
Crystal structure of UDP-glucose pyrophosphorylase from Yersinia pestis, a potential therapeutic target against plague ME Gibbs, GT Lountos, R Gumpena, DS Waugh Acta Crystallographica Section F: Structural Biology Communications 75 (9 …, 2019 | 5 | 2019 |
Study of quinoxaline-based new compounds against aminopeptidase N, and Plasmodium falciparum malarial parasite A Addlagatta, R Gumpena, A Marapaka, AD Allanki, JH Jun, PS Sijwali, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | 1 | 2014 |
CRYSTAL STRUCTURE OF THE UDP-GLUCOSE PYROPHOSPHORYLASE FROM YERSINIA PESTIS, AN ANTI-PLAGUE DRUG TARGET G Lountos, M Gibbs, R Gumpena, D Waugh PROTEIN SCIENCE 28, 105-105, 2019 | | 2019 |
Crystal Structure Of The UDP-Glucose Pyrophosphorylase From Yersinia Pestis, a Drug Target for New Anti-Plague Agents GT Lountos, ME Gibbs, R Gumpena, DS Waugh Foundations of Crystallography 75, a305, 2019 | | 2019 |
Full wwPDB X-ray Structure Validation Report i○ R Reddi, R Gumpena, C Kishor, A Addlagatta | | |
CONCISE ARTICLE C Kishor, VR Bommena, A Addlagatta | | |