Follow
Nathan LeBrasseur
Nathan LeBrasseur
Verified email at mayo.edu - Homepage
Title
Cited by
Cited by
Year
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
DJ Baker, T Wijshake, T Tchkonia, NK LeBrasseur, BG Childs, ...
Nature 479 (7372), 232-236, 2011
35782011
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
YI Zhu, T Tchkonia, T Pirtskhalava, AC Gower, H Ding, N Giorgadze, ...
Aging cell 14 (4), 644-658, 2015
19562015
Adverse events associated with testosterone administration
S Basaria, AD Coviello, TG Travison, TW Storer, WR Farwell, AM Jette, ...
New England Journal of Medicine 363 (2), 109-122, 2010
16972010
Senolytics improve physical function and increase lifespan in old age
M Xu, T Pirtskhalava, JN Farr, BM Weigand, AK Palmer, MM Weivoda, ...
Nature medicine 24 (8), 1246-1256, 2018
16372018
Cellular senescence mediates fibrotic pulmonary disease
MJ Schafer, TA White, K Iijima, AJ Haak, G Ligresti, EJ Atkinson, AL Oberg, ...
Nature communications 8 (1), 14532, 2017
12042017
Targeting cellular senescence prevents age-related bone loss in mice
JN Farr, M Xu, MM Weivoda, DG Monroe, DG Fraser, JL Onken, ...
Nature medicine 23 (9), 1072-1079, 2017
8902017
Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label, pilot study
JN Justice, AM Nambiar, T Tchkonia, NK LeBrasseur, R Pascual, ...
EBioMedicine 40, 554-563, 2019
8492019
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
LTJ Hickson, LGPL Prata, SA Bobart, TK Evans, N Giorgadze, SK Hashmi, ...
EBioMedicine 47, 446-456, 2019
839*2019
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals
C Handschin, S Chin, P Li, F Liu, E Maratos-Flier, NK LeBrasseur, Z Yan, ...
Journal of Biological Chemistry 282 (41), 30014-30021, 2007
7362007
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
M Xu, T Tchkonia, H Ding, M Ogrodnik, ER Lubbers, T Pirtskhalava, ...
Proceedings of the National Academy of Sciences 112 (46), E6301-E6310, 2015
6582015
High‐velocity resistance training increases skeletal muscle peak power in older women
RA Fielding, NK LeBrasseur, A Cuoco, J Bean, K Mizer, MAF Singh
Journal of the American Geriatrics Society 50 (4), 655-662, 2002
6212002
Targeting senescent cells enhances adipogenesis and metabolic function in old age
M Xu, AK Palmer, H Ding, MM Weivoda, T Pirtskhalava, TA White, A Sepe, ...
elife 4, e12997, 2015
5252015
Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice
Y Izumiya, T Hopkins, C Morris, K Sato, L Zeng, J Viereck, JA Hamilton, ...
Cell metabolism 7 (2), 159-172, 2008
4982008
The transcriptional coactivator PGC-1β drives the formation of oxidative type IIX fibers in skeletal muscle
Z Arany, N Lebrasseur, C Morris, E Smith, W Yang, Y Ma, S Chin, ...
Cell metabolism 5 (1), 35-46, 2007
4762007
High-intensity resistance training improves muscle strength, self-reported function, and disability in long-term stroke survivors
MM Ouellette, NK LeBrasseur, JF Bean, E Phillips, J Stein, WR Frontera, ...
Stroke 35 (6), 1404-1409, 2004
4612004
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
AK Palmer, M Xu, YI Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ...
Aging cell 18 (3), e12950, 2019
4482019
Identification of senescent cells in the bone microenvironment
JN Farr, DG Fraser, H Wang, K Jaehn, MB Ogrodnik, MM Weivoda, ...
Journal of Bone and Mineral Research 31 (11), 1920-1929, 2016
4252016
Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance
L Liu, D Brown, M McKee, NK LeBrasseur, D Yang, KH Albrecht, K Ravid, ...
Cell metabolism 8 (4), 310-317, 2008
4132008
Cellular senescence in type 2 diabetes: a therapeutic opportunity
AK Palmer, T Tchkonia, NK LeBrasseur, EN Chini, M Xu, JL Kirkland
Diabetes 64 (7), 2289-2298, 2015
3952015
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ...
The EMBO journal 38 (5), e100492, 2019
3652019
The system can't perform the operation now. Try again later.
Articles 1–20