Matthew Ranaghan
Matthew Ranaghan
Senior Research Scientist, Prime Medicine
Verified email at - Homepage
Cited by
Cited by
Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex
MF Tsai, CB Phillips, M Ranaghan, CW Tsai, Y Wu, C Williams, C Miller
eLife 5, e15545, 2016
Directed evolution of bacteriorhodopsin for applications in bioelectronics
NL Wagner, JA Greco, MJ Ranaghan, RR Birge
Journal of The Royal Society Interface 10 (84), 20130197, 2013
Proteolytic control of the mitochondrial calcium uniporter complex
CW Tsai, Y Wu, PC Pao, CB Phillips, C Williams, C Miller, M Ranaghan, ...
Proceedings of the National Academy of Sciences, USA, 201702938, 2017
Green proteorhodopsin reconstituted into nanoscale phospholipid bilayers (nanodiscs) as photoactive monomers
MJ Ranaghan, CT Schwall, NN Alder, RR Birge
Journal of the American Chemical Society 133 (45), 18318-18327, 2011
meso-Arylporpholactones and their Reduction Products
C Brückner, J Ogikubo, JR McCarthy, J Akhigbe, MA Hyland, ...
The Journal of Organic Chemistry 77 (15), 6480-6494, 2012
High-throughput screens to identify autophagy inducers that function by disrupting Beclin 1/Bcl-2 binding
WC Chiang, Y Wei, YC Kuo, S Wei, A Zhou, Z Zou, J Yehl, MJ Ranaghan, ...
ACS chemical biology 13 (8), 2247-2260, 2018
Molecular basis for substrate recruitment to the PRMT5 methylosome
KM Mulvaney, C Blomquist, N Acharya, R Li, MJ Ranaghan, M O’Keefe, ...
Molecular Cell 81 (17), 3481-3495. e7, 2021
Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase
CW Garvie, X Wu, M Papanastasiou, S Lee, J Fuller, GR Schnitzler, ...
Nature Communications 12 (1), 4375, 2021
Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction
DC McKinney, BJ McMillan, MJ Ranaghan, JA Moroco, M Brousseau, ...
Journal of Medicinal Chemistry 64 (15), 11148-11168, 2021
A second‐site suppressor of a folding defect functions via interactions with a chaperone network to improve folding and assembly in vivo
KN Parent, MJ Ranaghan, CM Teschke
Molecular Microbiology 54 (4), 1036-1050, 2004
Photochemical and thermal stability of green and blue proteorhodopsins: implications for protein-based bioelectronic devices
MJ Ranaghan, S Shima, L Ramos, DS Poulin, G Whited, S Rajasekaran, ...
The Journal of Physical Chemistry B 114 (44), 14064-14070, 2010
Assessing optimal: inequalities in codon optimization algorithms
MJ Ranaghan, JJ Li, DM Laprise, CW Garvie
BMC biology 19 (1), 1-13, 2021
The Autophagy-related Beclin-1 Protein requires both the Coiled-coil and BARA Domains to form a Homodimer with Sub-micromolar affinity
MJ Ranaghan, MA Durney, MF Mesleh, PR McCarren, CW Garvie, ...
Biochemistry 56 (51), 6639-6651, 2017
A Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca2+ to Recoverin
MJ Ranaghan, RP Kumar, KS Chakrabarti, V Buosi, D Kern, DD Oprian
Journal of Biological Chemistry 288 (50), 36160-36167, 2013
Photochromic Bacteriorhodopsin Mutant with High Holographic Efficiency and Enhanced Stability via a Putative Self-Repair Mechanism
MJ Ranaghan, JA Greco, NL Wagner, R Grewal, R Rangarajan, ...
ACS Applied Materials & Interfaces 6 (4), 2799-2808, 2014
Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state
PG Miller, M Sathappa, JA Moroco, W Jiang, Y Qian, S Iqbal, Q Guo, ...
Nature Communications 13 (1), 3778, 2022
Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF-Hands
RP Kumar, MJ Ranaghan, AY Ganjei, DD Oprian
Biochemistry 54 (49), 7222-7228, 2015
Biomolecular Electronics and Protein‐Based Optical Computing
JA Greco, NL Wagner, MJ Ranaghan, S Rajasekaran, RR Birge
Biomolecular information processing: from logic systems to smart sensors and …, 2012
Activation of retinal ganglion cells using a biomimetic artificial retina
BRR Greco JA, Wagner NL, Jensen RJ, Lawrence DB, Ranaghan MJ, Sandberg MN ...
J. Neural Eng.,, 2021
Optical applications of biomolecules
MJ Ranaghan, NL Wagner, MN Sandberg, RR Birge
Optical biomimetics: materials and applications (ed. Large, M.) 48, 20-78, 2012
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