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Patrick Hrdlicka
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Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): Tools for fundamental research, diagnostics, and nanotechnology
ME Østergaard, PJ Hrdlicka
Chemical Society Reviews 40 (12), 5771-5788, 2011
2232011
Multilabeled pyrene-functionalized 2 ‘-amino-LNA probes for nucleic acid detection in homogeneous fluorescence assays
PJ Hrdlicka, BR Babu, MD Sørensen, N Harrit, J Wengel
Journal of the American Chemical Society 127 (38), 13293-13299, 2005
1382005
C2′-pyrene-functionalized triazole-linked DNA: Universal DNA/RNA hybridization probes
SP Sau, PJ Hrdlicka
The Journal of organic chemistry 77 (1), 5-16, 2012
592012
Synthesis and hybridization studies of 2 ‘-amino-α-L-LNA and tetracyclic “Locked LNA”
TS Kumar, AS Madsen, J Wengel, PJ Hrdlicka
The Journal of Organic Chemistry 71 (11), 4188-4201, 2006
562006
DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles
D áEric Aston, A áLarry Branen
Chemical communications 48 (62), 7714-7716, 2012
502012
2′‐N‐(Pyren‐1‐yl)acetyl‐2′‐Amino‐α‐L‐LNA: Synthesis and Detection of Single Nucleotide Mismatches in DNA and RNA Targets
TS Kumar, J Wengel, PJ Hrdlicka
ChemBioChem 8 (10), 1122-1125, 2007
502007
Interstrand communication between 2′-N-(pyren-1-yl) methyl-2′-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity
PJ Hrdlicka, BR Babu, MD Sørensen, J Wengel
Chemical communications, 1478-1479, 2004
492004
Functionalized 2′-amino-α-L-LNA: directed positioning of intercalators for DNA targeting
TS Kumar, AS Madsen, ME Østergaard, SP Sau, J Wengel, PJ Hrdlicka
The Journal of organic chemistry 74 (3), 1070-1081, 2009
482009
Invader LNA: efficient targeting of short double stranded DNA
SP Sau, TS Kumar, PJ Hrdlicka
Organic & biomolecular chemistry 8 (9), 2028-2036, 2010
462010
Glowing locked nucleic acids: brightly fluorescent probes for detection of nucleic acids in cells
ME Østergaard, P Cheguru, MR Papasani, RA Hill, PJ Hrdlicka
Journal of the American Chemical Society 132 (40), 14221-14228, 2010
442010
Sensitive SNP Dual‐Probe Assays Based on Pyrene‐Functionalized 2′‐Amino‐LNA: Lessons To Be Learned
T Umemoto, PJ Hrdlicka, BR Babu, J Wengel
ChemBioChem 8 (18), 2240-2248, 2007
412007
Silica nanosprings coated with noble metal nanoparticles: Highly active SERS substrates
VVR Sai, D Gangadean, I Niraula, JMF Jabal, G Corti, DN McIlroy, ...
The Journal of Physical Chemistry C 115 (2), 453-459, 2011
402011
Nucleic acid structural engineering using pyrene-functionalized 2′-amino-α-L-LNA monomers and abasic sites
TS Kumar, AS Madsen, ME Østergaard, J Wengel, PJ Hrdlicka
The Journal of Organic Chemistry 73 (18), 7060-7066, 2008
372008
Gold-peptide nanoconjugate cellular uptake is modulated by serum proteins
G Wang, MR Papasani, P Cheguru, PJ Hrdlicka, RA Hill
Nanomedicine: Nanotechnology, Biology and Medicine, 2011
352011
C5‐Functionalized DNA, LNA, and α‐L‐LNA: Positional Control of Polarity‐Sensitive Fluorophores Leads to Improved SNP‐Typing
ME Østergaard, P Kumar, B Baral, DC Guenther, BA Anderson, ...
Chemistry–A European Journal 17 (11), 3157-3165, 2011
332011
Pyrene-functionalized triazole-linked 2′-deoxyuridines—probes for discrimination of single nucleotide polymorphisms (SNPs)
ME Østergaard, DC Guenther, P Kumar, B Baral, L Deobald, ...
Chemical communications 46 (27), 4929-4931, 2010
322010
Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA
SP Sau, AS Madsen, P Podbevsek, NK Andersen, TS Kumar, S Andersen, ...
The Journal of organic chemistry 78 (19), 9560-9570, 2013
302013
Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3′-C-ethynyluridine (EUrd) and 3′-C-ethynylcytidine (ECyd)
PJ Hrdlicka, JS Jepsen, C Nielsen, J Wengel
Bioorganic & medicinal chemistry 13 (4), 1249-1260, 2005
292005
High-Affinity DNA Targeting Using Readily Accessible Mimics of N2′-Functionalized 2′-Amino-α-L-LNA
S Karmakar, BA Anderson, RL Rathje, S Andersen, TB Jensen, P Nielsen, ...
The Journal of organic chemistry 76 (17), 7119-7131, 2011
282011
Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid)
P Kumar, ME Østergaard, B Baral, BA Anderson, DC Guenther, M Kaura, ...
The Journal of organic chemistry 79 (11), 5047-5061, 2014
272014
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