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Selina Yijia Li Holbrook
Selina Yijia Li Holbrook
Verified email at uky.edu
Title
Cited by
Cited by
Year
New trends in the use of aminoglycosides
MY Fosso, Y Li, S Garneau-Tsodikova
MedChemComm 5 (8), 1075-1091, 2014
922014
Inhibition of aminoglycoside acetyltransferase resistance enzymes by metal salts
Y Li, KD Green, BR Johnson, S Garneau-Tsodikova
Antimicrobial Agents and Chemotherapy 59 (7), 4148-4156, 2015
562015
Repurposing antipsychotic drugs into antifungal agents: Synergistic combinations of azoles and bromperidol derivatives in the treatment of various fungal infections
SYL Holbrook, A Garzan, EK Dennis, SK Shrestha, S Garneau-Tsodikova
European Journal of Medicinal Chemistry 139, 12-21, 2017
462017
Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis …
A Garzan, MJ Willby, HX Ngo, CS Gajadeera, KD Green, SYL Holbrook, ...
ACS infectious diseases 3 (4), 302-309, 2017
442017
Evaluation of Aminoglycoside and Carbapenem Resistance in a Collection of Drug-Resistant Pseudomonas aeruginosa Clinical Isolates
SYL Holbrook, S Garneau-Tsodikova
Microbial drug resistance 24 (7), 1020-1030, 2018
412018
Potent 1,2,4-Triazino[5,6b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis
HX Ngo, KD Green, CS Gajadeera, MJ Willby, SYL Holbrook, C Hou, ...
ACS infectious diseases 4 (6), 1030-1040, 2018
212018
Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from Mycobacterium tuberculosis
A Punetha, HX Ngo, SYL Holbrook, KD Green, MJ Willby, SA Bonnett, ...
ACS chemical biology 15 (6), 1581-1594, 2020
162020
Expanding aminoglycoside resistance enzyme regiospecificity by mutation and truncation
SYL Holbrook, S Garneau-Tsodikova
Biochemistry 55 (40), 5726-5737, 2016
122016
What is medicinal chemistry?–Demystifying a rapidly evolving discipline!
SYL Holbrook, S Garneau-Tsodikova
MedChemComm 8 (9), 1739-1741, 2017
102017
Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from Mycobacterium tuberculosis to overcome kanamycin resistance
A Punetha, KD Green, A Garzan, NT Chandrika, MJ Willby, AH Pang, ...
RSC Medicinal Chemistry 12 (11), 1894-1909, 2021
92021
Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity
AH Pang, KD Green, NT Chandrika, A Garzan, A Punetha, SYL Holbrook, ...
European journal of medicinal chemistry 242, 114698, 2022
62022
Emerging targets in anti-tubercular drug design
KD Green, SYL Holbrook, HX Ngo, S Garneau-Tsodikova
22017
Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from Mycobact
A Punetha, KD Green, A Garzan, NT Chandrika, MJ Willby, AH Pang, ...
RSC Med. Chem. 11 (12)), 2021
2021
Antifungal Compositions
S Garneau-Tsodikova, A Garzan, SYL Holbrook, EK Dennis
US Patent App. 16/038,171, 2019
2019
Discovery of New Antimicrobial Options and Evaluation of Aminoglycoside Resistance Enzyme-associated Resistance Epidemic
SYL Holbrook
2018
Nucleoside triphosphate cosubstrates control the substrate profile and efficiency of aminoglycoside 3′-O-phosphotransferase type IIa
SYL Holbrook, MS Gentry, OV Tsodikov, S Garneau-Tsodikova
MedChemComm 9 (8), 1332-1339, 2018
2018
Supporting Information Nucleoside triphosphate cosubstrates control the substrate profile and efficiency of aminoglycoside 3'-O-phosphotransferase type IIa
SYL Holbrook, MS Gentry, OV Tsodikov, S Garneau-Tsodikovaa
Broadening the field of opportunity for medicinal chemists rsc. li/medchemcomm
SYL Holbrook, S Garneau-Tsodikova
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