Nils Billestrup
Nils Billestrup
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The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into α and subsequently β cells
P Collombat, X Xu, P Ravassard, B Sosa-Pineda, S Dussaud, N Billestrup, ...
Cell 138 (3), 449-462, 2009
Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro
N Billestrup, LW Swanson, W Vale
Proceedings of the National Academy of Sciences 83 (18), 6854-6857, 1986
Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling
TE Adams, JA Hansen, R Starr, NA Nicola, DJ Hilton, N Billestrup
Journal of Biological Chemistry 273 (3), 1285-1287, 1998
Growth hormone, interferon-γ, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1
LS Argetsinger, GW Hsu, MG Myers, N Billestrup, MF White, C Carter-Su
Journal of Biological Chemistry 270 (24), 14685-14692, 1995
Regulation of beta-cell mass by hormones and growth factors.
JH Nielsen, ED Galsgaard, A Møldrup, BN Friedrichsen, N Billestrup, ...
Diabetes 50 (suppl 1), S25, 2001
The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.
LS Smit, DJ Meyer, N Billestrup, G Norstedt, J Schwartz, C Carter-Su
Molecular endocrinology 10 (5), 519-533, 1996
Proliferation of sorted human and rat beta cells
G Parnaud, D Bosco, T Berney, F Pattou, J Kerr-Conte, MY Donath, ...
Diabetologia 51 (1), 91-100, 2008
Cytokines and β-cell biology: from concept to clinical translation
MY Donath, J Størling, LA Berchtold, N Billestrup, T Mandrup-Poulsen
Endocrine reviews 29 (3), 334-350, 2008
Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
JA Hansen, K Lindberg, DJ Hilton, JH Nielsen, N Billestrup
Molecular Endocrinology 13 (11), 1832-1843, 1999
Proinflammatory cytokines activate the intrinsic apoptotic pathway in β-cells
LG Grunnet, R Aikin, MF Tonnesen, S Paraskevas, L Blaabjerg, J Størling, ...
Diabetes 58 (8), 1807-1815, 2009
Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus
DP Christensen, M Dahllöf, M Lundh, DN Rasmussen, MD Nielsen, ...
Molecular medicine 17 (5-6), 378-390, 2011
Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling
CJ Greenhalgh, D Metcalf, AL Thaus, JE Corbin, R Uren, PO Morgan, ...
Journal of Biological Chemistry 277 (43), 40181-40184, 2002
Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase.
JA VanderKuur, X Wang, L Zhang, GS Campbell, G Allevato, N Billestrup, ...
Journal of Biological Chemistry 269 (34), 21709-21717, 1994
Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2
J VanderKuur, G Allevato, N Billestrup, G Norstedt, C Carter-Su
Journal of Biological Chemistry 270 (13), 7587-7593, 1995
Suppressor of cytokine signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex
H Frobøse, S Groth Rønn, PE Heding, H Mendoza, P Cohen, ...
Molecular endocrinology 20 (7), 1587-1596, 2006
Beta cell proliferation and growth factors
JH Nielsen, C Svensson, ED Galsgaard, A Møldrup, N Billestrup
Journal of molecular medicine 77 (1), 62-66, 1999
Pituitary adenomas in mice transgenic for growth hormone-releasing hormone
SL Asa, K Kovacs, L Stefaneanu, E Horvath, N Billestrup, ...
Endocrinology 131 (5), 2083-2089, 1992
Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt
J Størling, J Binzer, AK Andersson, RA Züllig, M Tonnesen, R Lehmann, ...
Diabetologia 48 (10), 2039-2050, 2005
Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B
MR Stofega, J Herrington, N Billestrup, C Carter-Su
Molecular endocrinology 14 (9), 1338-1350, 2000
Suppressor of cytokine signaling 3 (SOCS-3) protects β-cells against interleukin-1β-and interferon-γ-mediated toxicity
AE Karlsen, SG Rønn, K Lindberg, J Johannesen, ED Galsgaard, F Pociot, ...
Proceedings of the National Academy of Sciences 98 (21), 12191-12196, 2001
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