Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis I Daehn, G Casalena, T Zhang, S Shi, F Fenninger, N Barasch, L Yu, ... The Journal of clinical investigation 124 (4), 1608-1621, 2014 | 310 | 2014 |
Glomerular endothelial mitochondrial dysfunction is essential and characteristic of diabetic kidney disease susceptibility H Qi, G Casalena, S Shi, L Yu, K Ebefors, Y Sun, W Zhang, V D’Agati, ... Diabetes, db160695, 2016 | 230 | 2016 |
The glomerular filtration barrier: a structural target for novel kidney therapies IS Daehn, JS Duffield Nature Reviews Drug Discovery 20 (10), 770-788, 2021 | 161 | 2021 |
Transforming growth factor-β, bioenergetics, and mitochondria in renal disease G Casalena, I Daehn, E Bottinger Seminars in nephrology 32 (3), 295-303, 2012 | 125 | 2012 |
Molecular mechanisms in early diabetic kidney disease: glomerular endothelial cell dysfunction E Lassén, IS Daehn International journal of molecular sciences 21 (24), 9456, 2020 | 121 | 2020 |
Novel filtration markers as predictors of all-cause and cardiovascular mortality in US adults MC Foster, LA Inker, AS Levey, E Selvin, J Eckfeldt, SP Juraschek, ... American journal of kidney diseases 62 (1), 42-51, 2013 | 95 | 2013 |
Biological variability of estimated GFR and albuminuria in CKD SS Waikar, CM Rebholz, Z Zheng, S Hurwitz, C Hsu, HI Feldman, D Xie, ... American Journal of Kidney Diseases 72 (4), 538-546, 2018 | 93 | 2018 |
Epithelial cell TGFβ signaling induces acute tubular injury and interstitial inflammation ME Gentle, S Shi, I Daehn, T Zhang, H Qi, L Yu, VD D’Agati, ... Journal of the American Society of Nephrology 24 (5), 787-799, 2013 | 93 | 2013 |
Endothelin receptor-A mediates degradation of the glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells K Ebefors, RJ Wiener, L Yu, EU Azeloglu, Z Yi, F Jia, W Zhang, MH Baron, ... Kidney international 96 (4), 957-970, 2019 | 91 | 2019 |
Krüppel-like factor 6 regulates mitochondrial function in the kidney SK Mallipattu, SJ Horne, V D’Agati, G Narla, R Liu, MA Frohman, ... The journal of clinical investigation 125 (3), 1347-1361, 2015 | 89 | 2015 |
Glomerular endothelial cell stress and cross-talk with podocytes in early diabetic kidney disease IS Daehn Frontiers in medicine 5, 76, 2018 | 79 | 2018 |
The diabetic microenvironment causes mitochondrial oxidative stress in glomerular endothelial cells and pathological crosstalk with podocytes GA Casalena, L Yu, R Gil, S Rodriguez, S Sosa, W Janssen, EU Azeloglu, ... Cell Communication and Signaling 18, 1-15, 2020 | 58 | 2020 |
Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro G Casalena, S Krick, I Daehn, L Yu, W Ju, S Shi, S Tsai, V D'Agati, ... American Journal of Physiology-Renal Physiology 306 (11), F1372-F1380, 2014 | 57 | 2014 |
Regulation of MAPK activation, AP-1 transcription factor expression and keratinocyte differentiation in wounded fetal skin S Gangnuss, AJ Cowin, IS Daehn, N Hatzirodos, JA Rothnagel, ... Journal of investigative dermatology 122 (3), 791-804, 2004 | 57 | 2004 |
Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation R Brem, I Daehn, P Karran DNA repair 10 (8), 869-876, 2011 | 54 | 2011 |
Bcl-xL overexpression protects from apoptosis induced by HMG-CoA reductase inhibitors in murine tubular cells LM Blanco-Colio, P Justo, I Daehn, C Lorz, A Ortiz, J Egido Kidney international 64 (1), 181-191, 2003 | 47 | 2003 |
Modeling the glomerular filtration barrier and intercellular crosstalk K Ebefors, E Lassén, N Anandakrishnan, EU Azeloglu, IS Daehn Frontiers in Physiology 12, 689083, 2021 | 36 | 2021 |
6-Thioguanine damages mitochondrial DNA and causes mitochondrial dysfunction in human cells I Daehn, R Brem, E Barkauskaite, P Karran FEBS letters 585 (24), 3941-3946, 2011 | 34 | 2011 |
Cross-disciplinary biomarkers research: lessons learned by the CKD Biomarkers Consortium C Hsu, S Ballard, D Batlle, JV Bonventre, EP Böttinger, HI Feldman, ... Clinical Journal of the American Society of Nephrology 10 (5), 894-902, 2015 | 30 | 2015 |
WT1 is necessary for the proliferation and migration of cells of renin lineage following kidney podocyte depletion NV Kaverina, DG Eng, AD Largent, I Daehn, A Chang, KW Gross, ... Stem Cell Reports 9 (4), 1152-1166, 2017 | 29 | 2017 |