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Stefania Girotto
Stefania Girotto
Team Leader, Fondazione Istituto Italiano di Tecnologia
Verified email at iit.it
Title
Cited by
Cited by
Year
Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS
L Banci, I Bertini, A Durazo, S Girotto, EB Gralla, M Martinelli, JS Valentine, ...
Proceedings of the National Academy of Sciences 104 (27), 11263-11267, 2007
2792007
SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization
L Banci, I Bertini, M Boca, S Girotto, M Martinelli, JS Valentine, M Vieru
PloS one 3 (2), e1677, 2008
2562008
Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants
L Banci, I Bertini, M Boca, V Calderone, F Cantini, S Girotto, M Vieru
Proceedings of the National Academy of Sciences 106 (17), 6980-6985, 2009
1422009
DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function
N Plotegher, G Berti, E Ferrari, I Tessari, M Zanetti, L Lunelli, E Greggio, ...
Scientific reports 7 (1), 40699, 2017
1302017
Reduced affinity for isoniazid in the S315T mutant ofMycobacterium tuberculosis KatG is a key factor in antibiotic resistance
S Yu, S Girotto, C Lee, RS Magliozzo
Journal of Biological Chemistry 278 (17), 14769-14775, 2003
1282003
DJ-1 is a copper chaperone acting on SOD1 activation
S Girotto, L Cendron, M Bisaglia, I Tessari, S Mammi, G Zanotti, ...
Journal of Biological Chemistry 289 (15), 10887-10899, 2014
1032014
Dopamine-derived quinones affect the structure of the redox sensor DJ-1 through modifications at Cys-106 and Cys-53
S Girotto, M Sturlese, M Bellanda, I Tessari, R Cappellini, M Bisaglia, ...
Journal of Biological Chemistry 287 (22), 18738-18749, 2012
862012
Identification and Characterization of Tyrosyl Radical Formation in Mycobacterium tuberculosisCatalase-Peroxidase (KatG)
S Chouchane, S Girotto, S Yu, RS Magliozzo
Journal of Biological Chemistry 277 (45), 42633-42638, 2002
842002
Rapid formation of compound II and a tyrosyl radical in the Y229F mutant of Mycobacterium tuberculosis catalase-peroxidase disrupts catalase but not peroxidase function
S Yu, S Girotto, X Zhao, RS Magliozzo
Journal of Biological Chemistry 278 (45), 44121-44127, 2003
732003
Analysis of heme structural heterogeneity in Mycobacterium tuberculosis catalase-peroxidase (KatG)
S Chouchane, S Girotto, S Kapetanaki, JPM Schelvis, S Yu, RS Magliozzo
Journal of Biological Chemistry 278 (10), 8154-8162, 2003
612003
Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase
D Pizzirani, A Bach, N Realini, A Armirotti, L Mengatto, I Bauer, S Girotto, ...
Angewandte Chemie 127 (2), 495-499, 2015
452015
Keys to lipid selection in fatty acid amide hydrolase catalysis: structural flexibility, gating residues and multiple binding pockets
G Palermo, I Bauer, P Campomanes, A Cavalli, A Armirotti, S Girotto, ...
PLoS computational biology 11 (6), e1004231, 2015
442015
Evidence for radical formation at Tyr-353 in Mycobacterium tuberculosis catalase-peroxidase (KatG)
X Zhao, S Girotto, S Yu, RS Magliozzo
Journal of Biological Chemistry 279 (9), 7606-7612, 2004
432004
Conformational differences in Mycobacterium tuberculosis catalase-peroxidase KatG and its S315T mutant revealed by resonance Raman spectroscopy
S Kapetanaki, S Chouchane, S Girotto, S Yu, RS Magliozzo, JPM Schelvis
Biochemistry 42 (13), 3835-3845, 2003
402003
Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells
M Roberti, F Schipani, G Bagnolini, D Milano, E Giacomini, F Falchi, ...
European Journal of Medicinal Chemistry 165, 80-92, 2019
382019
Investigating drug–target residence time in kinases through enhanced sampling simulations
D Gobbo, V Piretti, RMC Di Martino, SK Tripathi, B Giabbai, P Storici, ...
Journal of Chemical Theory and Computation 15 (8), 4646-4659, 2019
372019
Synthetic lethality in pancreatic cancer: Discovery of a new RAD51-BRCA2 small molecule disruptor that inhibits homologous recombination and synergizes with olaparib
G Bagnolini, D Milano, M Manerba, F Schipani, JA Ortega, D Gioia, ...
Journal of Medicinal Chemistry 63 (5), 2588-2619, 2020
332020
Radical sites in Mycobacterium tuberculosis KatG identified using electron paramagnetic resonance spectroscopy, the three-dimensional crystal structure, and electron transfer …
K Ranguelova, S Girotto, GJ Gerfen, S Yu, J Suarez, L Metlitsky, ...
Journal of biological chemistry 282 (9), 6255-6264, 2007
332007
NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells
N Plotegher, C Stringari, S Jahid, M Veronesi, S Girotto, E Gratton, ...
The FASEB Journal 29 (6), 2484, 2015
322015
Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis
E Ferrari, M Engelen, E Monzani, M Sturini, S Girotto, L Bubacco, L Zecca, ...
JBIC Journal of Biological Inorganic Chemistry 18, 81-93, 2013
292013
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